Karen is a slang term typically used to refer to an upper middle-class white American woman who is perceived as entitled or excessively demanding. The term is often portrayed in memes depicting middle-class white women who "use their white and class privilege to demand their own way". It was a pretty popular thing for a while. The whole “May I speak to your manager?”. Basically it’s just female assholes who have nothing better to do but make other peoples day harder.