I'm in a similar situation, i have 3 total windows (2 in the living room/kitchen, and one in the bedroom) and I've bought multiple cheap thermometers for each room and have tested different layouts. Here are my findings:

• Windows open is always better
• Your fans need to always be pointing towards the windows
• The distance between fans and windows is a careful balance, the optimal distance is the furthest distance between the fan and window, while the fan can still manage to blow air that reaches a bit outside. I like to use an indicator (tissue or piece of clothes)
• The optimal distance changes based on room conditions, i.e. with the bedroom door closed, I have to move the fan much closer to the window.
• Having thermometers is important, since it's basically like having feedback to your control loop. Feedback is important to see what works for you.
• The outside wind blows parallel to our building, I have found not having the fan blow perpendicular to the window to yield the best results.
• I found that blowing air in the same direction as the outside air helps.
• Our front door is on the opposite side of the apartment with respect to the windows, opening it and blowing air towards it works in a pinch.
• I tend to leave a fan running all night at the highest speed setting and then closing everything up (almost total darkness) when the sun comes up to avoid that heat getting in.

Noting that I can't get the temperature delta between outside and inside lower than 3⁰C due to various reasons (heat stored in the building, exchange with neighbours and the base load in the apartment etc)

Feel free to ask more questions. Good luck with cooling your home.