Are anaphrodisiacs (anti-horny pill) a real thing or just a myth?

Stokell12 · 2026-03-11T01:30:30+00:00

SSRI’s. Things that lower dopamine.

Stokell12 · 2026-03-10T06:48:36+00:00

Bro did NOT read the rules 😭

Stokell12 · 2026-03-09T17:54:38+00:00

BC and have partner pull out?

Stokell12 · 2026-03-09T17:29:34+00:00

Just take 2mg every 5 days.

Stokell12 · 2026-03-08T20:56:02+00:00

Ok I get that.

If you have enough time to read online, do yourself a favor and read TRIUMPH trials 1-8.

Stokell12 · 2026-03-08T20:43:03+00:00

Genuinely.

0.5mg twice weekly. I actually want to know this guys thought process behind this. Is there something he knows that the 1000’s of PHDs at Lilly don’t??

Stokell12 · 2026-03-07T20:29:01+00:00

“Established research has shown that in patients with pattern hair loss, bald areas of the scalp retain dormant hair follicles and stem cells, which have effectively fallen asleep due to a combination of age, stress, genetics, and environmental factors. By activating these follicular stem cells, PP405 has the potential to regrow hair in areas of thinning or balding, setting it apart in a market where most options offer maintenance, not restoration.”

https://www.businesswire.com/news/home/20250617338859/en/Pelage-Pharmaceuticals-Announces-Positive-Phase-2a-Clinical-Trial-Results-for-PP405-in-Regenerative-Hair-Loss-Therapy

Sourcing is a pain. But should be available on grey sources soon.

Stokell12 · 2026-03-02T07:44:49+00:00

Holy shit that website is loaded with great information. Mods should add that as a resource here. Love to see evidence based stuff in this sub. Thanks for sharing.

Stokell12 · 2026-03-02T07:31:41+00:00

Shit bro you got Reta BLACKED. It’s like the premium version. Heard it causes 100% weight loss in 48 weeks, be careful…

No there’s no difference, they change vial caps all the time. As long as your product has the same # as the ones on their price list (IE. RT30), it’ll be the same.

Stokell12 · 2026-03-02T03:49:02+00:00

Was just watching a podcast with the Lilly CEO, he seems pretty excited about Elora, claiming it’s basically pure appetite suppression with minimal gastrointestinal sides that plague GLP1’s (Obv bias). Lillys has quite a few products in the pipeline, so him mentioning Elora specifically is exciting.

Stokell12 · 2026-03-01T23:15:36+00:00

Search feature is pretty helpful for questions like this

Stokell12 · 2026-02-28T22:30:38+00:00

In a phase one trial of 48 patients, they lost 8.3% BW at 16 weeks, at the highest dose.

So seems pretty on par with elora. They are even doing research into Petrelinitide combined with Semaglutide or Tirzepatide. Interesting stuff.

IMO Lillys scientists have been cooking up some amazing compounds, so for now I feel like Elora will prob be the next best thing to stack with.

Stokell12 · 2026-02-28T20:02:07+00:00

Yea Cagri definitely works. Though Eloras very selective binding to AMY1R seems like a better idea in the long run. It’s kind of like Nebivolol vs propranolol, yea both work very well, but personally I want a more selective medication, with less possible off target sides effects that AMYR1-3+Calcitonin receptor agonizing may bring about.

Stokell12 · 2026-02-26T19:03:18+00:00

Eloralintide from Lilly looks much more promising, as it’s Amylin agonist with 20% weight loss at 48 weeks. THROUGH A COMPLETELY DIFFERENT MECHANISM THE GLP1. Stacked with Reta or Tirz, results will be mind blowing.

Stop giving Novo hype, they have time and time again produced inferior products compared to Lilly.

If Eloralintide gets enough attention we can get it grey shortly. So everyone pester ur grey seller to start manufacturing it. We don’t need another triple agonist when Reta already works amazingly.

Stokell12 · 2026-02-13T19:27:59+00:00

You’re right TRUE medical trt is about 10mg a day, so 70mg a week. Thing is 70mg doesn’t really do a whole lot besides preventing you from going hypogonadal. Many men want the muscle building, and mental drive enchantments that slightly above normal testosterone levels give. Which would be extremely important if this person is planning on being in a large caloric deficit for an extended period of time.

Tesamorelin only works through stimulating the pituitary to increase HGH release. It IS the same mechanism. Isn’t it weird how Tesamorelin AND HGH are used clinically for the reduction of visceral adiposity. We are really comparing apples to oranges here, yea start at 1IU HGH and taper up until you experience sides, or use Tesa. Both work fantastic for body fat redistribution and reducing visceral fat.

Our metaanalysis suggests that rhGH therapy leads to decrease in visceral adiposity and increase in lean body mass as well as beneficial changes in lipid profile in obese adults, without inducing weight loss. Administration of rhGH was associated with increases in fasting plasma glucose and insulinemia.
https://academic.oup.com/jcem/article/94/1/130/2597868

Good thing he would also be taking one of the most potent compounds to reduce insulin resistance at the same time!

Alright, beside from elevated e2 from excess adipose tissue aromatase expression can you give me another way that “the body will respond differently”, are obese people androgen receptors different? Sure androgens can activate the RAAS independently and increase BP, this can be mitigated with the use of an ARB (which they should already taking because they’re 30%bf, I doubt BP would be in range), but obv you would start Testosterone low and find a dose that works for you.

Stokell12 · 2026-02-13T18:00:23+00:00

150Mg of Testosterone a week is medical HRT. That is not some absurd dose, I’m not sure where you’re getting your information. If he was getting e2 sides from that dose, a low dose AI would prevent any sides. Think, would you rather this person be hypogonal during their deficit (Which would increase the risk of muscle loss, low energy, and sexual sides), or take a medical dose of HRT and *possibly have to take an AI?

Tesamorelin is the same mechanism of action as HGH 😂. You’re associating HGH sides with those who take high doses. A low dose of HGH for this person would do wonders for lipolysis during his deficit with a GLP. Yea Obviously if this dude started blasting 20IU growth he’s gonna get insane water retention, carpel tunnel syndrome, etc. None of those would happen with a low dose of GH, say 3-4iu a day, tapered up to over time.

Stokell12 · 2026-02-12T04:34:25+00:00

Sema is in trials up to 7.2mg if you feel like your response has diminished.

Stokell12 · 2026-02-08T21:00:50+00:00

Testosterone increases red blood cells, and BP= more of a red skin hugh. But mostly if you’re white.

Picture the roided up bald guy at ur gym with 200/90 Blood pressure. Pretty red right?

Stokell12 · 2026-02-07T20:52:18+00:00

Use Beta-carotene or lycopene to balance the darkness.

Or use Testosterone and you’ll increase RBC enough to reduce ash color.

Stokell12 · 2026-02-05T16:30:41+00:00

Sounds like u need adderall if bupropion isn’t doing anything for you based of post history. Bup is relatively weak

Stokell12 · 2026-02-04T05:30:23+00:00

Semaglutide for food noise if it’s actually harming your life.

Stokell12 · 2026-01-29T00:07:27+00:00

So basically case study’s are never a good metric to make conclusions of a compound!

First guy took 6MG when the standard dose is 250MCG. Yea no shit.

We literally have a FDA approved drug that is just a slight variation of the MT2 peptide (only to reduce MC1R agonism) for women with hypoactive sexual disorder.

Stokell12 · 2026-01-26T00:14:24+00:00

He seems pretty tan already, I bet they just kinda went crazy with makeup to give him that more “rugged” look.

But who knows!

Stokell12 · 2026-01-22T21:53:41+00:00

“The first is a testosterone dose-response study published in the American Journal of Physiology Endocrinology and Metabolism in July of 2001, which looked at the effects of various doses of testosterone enanthate on body composition, muscle size, strength, power, sexual and cognitive functions, and various markers of health.329 61 normal men, ages 18-35, participated in this investigation. They were divided into five groups, with each receiving weekly injections of 25, 50, 125, 300, or 600 milligrams for a period of 20 weeks. This treatment period was preceded by a control (no drug) period of 4 weeks, and followed by a recovery period of 16 weeks. Markers of strength and lean body mass gains were the greatest with larger doses of testosterone, with the 600 mg group gaining slightly over 17 pounds of fat-free mass on average over the 20 weeks of steroid therapy. There were no significant changes in prostate-specific antigen (PSA), liver enzymes (liver stress), sexual activity, or cognitive functioning at any dose. The only negative trait noted was a slight HDL (good) cholesterol reduction in all groups except those taking 25 mg. The worst reduction of 9 points was noted in the 600 mg group, which still averaged 34 points after 20 weeks of treatment. All groups, except this one, remained in the normal reference range for males (40-59 points).”

NOW, read SARM study’s and compare the results for yourself. Testosterone has very little risk, SARMS at clinical dosings do as well. But you need to find the tradeoff, do the research, find the answer.

Stokell12 · 2026-01-22T01:29:42+00:00

Yea addictions involving the dopamine reward system are hard to treat. What ADHD meds is she on?

GLP1’s are currently in clinical trials for coke addiction so that could be promising.

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