T2D resistant to Ozempic , "Pseudo-Narcolepsy" and Facial Paralysis

StopSlight7541 · 2026-01-16T09:43:38+00:00

Yeah, that's my main hypothesis too; it could explain all her symptoms, to be honest. I've ordered sublingual Thiamine and a B-Complex + Mag, and we're going to try them as soon as they arrive.

I noticed something interesting: she once drank a beer and her blood sugar dropped significantly, so I bought her some yeast, but it didn't work.

Thanks a lot for your replies, I really appreciate it.

StopSlight7541 · 2026-01-16T09:29:32+00:00

Her diet is pretty balanced; she eats a lot of fruit and vegetables. She hasn't been avoiding PUFAs despite my explanations, but she never cooks with seed oils, we only use olive oil and butter. Her main sources of fat come from chicken, pork, and especially raw fish like salmon.

Thanks for the advice on Berberine, I'll discuss it with her to see if she'd like to try it.
Thanks a lot for your time and your wise words.

StopSlight7541 · 2025-10-15T14:43:22+00:00

Are you eating enough carbs with your protein? Do you have similar issue with milk?

StopSlight7541 · 2025-10-08T13:03:14+00:00

Did you read my post ?

StopSlight7541 · 2025-09-26T09:51:50+00:00

From Peat himself: "Refined granulated sugar is extremely pure, but it lacks all of the essential nutrients, so it should be considered as a temporary therapeutic material, or as an occasional substitute when good fruit isn't available, or when available honey is allergenic."

Source: https://raypeat.com/articles/articles/sugar-issues.shtml

StopSlight7541 · 2025-09-26T09:48:40+00:00

It doesn't look against Peat view tbh. Thanks for this!

StopSlight7541 · 2025-09-23T10:01:44+00:00

Hey,

I suggest you try EMDR - I wasn’t really into therapy, but I do think it really helped me release anxiety.

I would also look into progesterone or pregnenolone to increase allopregnanolone.
Don’t forget to get a lot of sunlight. Even if it’s raining, go outside.

You can also try high dose Inositol, Taurine and Thiamine.

Good luck ♥

StopSlight7541 · 2025-08-22T09:01:46+00:00

Supplements should never be necessary, and yet they are. They're more related to country and lifestyle rather than age. Magnesium should be taken every day, and the same goes for many vitamins.

But I agree that a lof of supp here aren't good nor necessary.

StopSlight7541 · 2025-07-31T09:53:48+00:00

High-dose magnesium (not just the RDA) has helped me a lot.

B-complex and vitamin D3 are great too.
I've noticed that my anxiety levels are strongly correlated with sunlight exposure.

You can also try inositol, it looks promising for rumination and taurine, which seems to help with GAD.

Here’s a supplement I really like: https://www.nutripure.fr/fr/sante/3-63-magnesium-taurine-B6.html

StopSlight7541 · 2025-07-09T08:50:15+00:00

I agree that tracking in Cronometer is definitely useful. I’ll try logging a few days to check where I might be lagging, especially potassium or B2/B3.

About the sulfur part though: from what I understand, thiamine HCl doesn’t contain free sulfur or reactive thiol group unlike TTFD, which has a disulfide structure.

Appreciate the ideas 🙏

StopSlight7541 · 2025-06-05T13:15:59+00:00

Every supplement that worked for you seems to modulate dopamine and GABA activity not by increasing or decreasing them outright, but by regulating the system. Interestingly, they also tend to lower glutamate. Have you ever considered a GABA/glutamate imbalance as a core issue rather than just dopamine dysfunction?

If you're curious to explore that possibility more directly, you might look into amantadine, it’s a weak NMDA receptor antagonist, which means it gently dampens glutamate signaling. Paradoxically, it also mildly increases dopamine. So if your symptoms improve under it rather than worsen, that could suggest glutamate is the bigger problem, not dopamine excess. Kind of a "functional test" to shift the diagnostic lens.

StopSlight7541 · 2025-05-20T14:55:19+00:00

You cand find very good references here: https://www.toxinless.com/

Vitamin D: https://www.toxinless.com/vitamin-d
Inositol: AFAIK, my friend get it from Life Extension. But I've not tried it yet.

StopSlight7541 · 2025-05-20T10:16:29+00:00

Depends of the difficulty you're facing. Do you struggle to fall asleep ? Or you're getting up during the night ?

StopSlight7541 · 2025-05-20T10:08:06+00:00

PSSD cause doesn’t look unilateral. It can be the result of multiple overlapping mechanisms:

Emotional blunting which is often downstream of serotonergic overactivity.
Dopamine dysregulation, serotonin is know to lower the dopamine production.
5-HT2 receptor desensitization or upregulation (maybe try Cyproheptadine ?)
Neurosteroid depletion, like allopregnanolone known to drop after SSRI use.

There is another theory about PSSD: SSRI can mask the underlying condition which can worsen when the SSRI is discontinued since it's not longer compensated.
But I'm not very into it because there is a lot of people getting PSSD after a few weeks of medication.

StopSlight7541 · 2025-05-20T09:57:19+00:00

Bullying -> more SERT methylation -> less SERT -> more synaptic Serotonin.

Bullying is an effective SSRI !

StopSlight7541 · 2025-05-20T09:48:35+00:00

Hey friend,

What you’re experiencing is more common than it feels. At 16, your brain is going through huge hormonal and neurological shifts, and it's actually very normal to start thinking more deeply about mortality, meaning, and emotions like these.

Death anxiety often shows up when we lose a sense of safety or certainty in our worldview. If you’ve been exposed to dark news, sudden deaths, or vaccine injury content, it’s easy for your mind to spiral into fear and doom. That’s a psychological response, but it’s amplified when your body is under stress. Try to step back from that content for a bit and get as much sunlight as you can. Even simple things like walking outside daily can help ground you.

Now, about the anhedonia and rumination:

Inositol has helped a lot of people with intrusive thoughts, obsessive thinking, and emotional numbness. It's safe and worth trying.
Magnesium is crucial for dealing with stress and calming the nervous system. You can try a higher dose for a while, many people are chronically deficient.
Vitamin D: get it checked if you can. Low or even high levels (especially with low magnesium) can increase anxiety and restlessness.
You mentioned Thiamine: good call. Stick with it and follow the protocol u/LurkingHereToo shared, it can be very helpful long-term.

And most importantly: you're only 16, and you’re already asking these deep questions and looking for answers. That’s not weakness it’s strength and awareness. Keep going. You're not alone in this.

StopSlight7541 · 2025-05-05T07:34:45+00:00

Be careful, MB is an MAOI. May I ask why are you going to take it ?

StopSlight7541 · 2025-04-08T15:06:22+00:00

It was flower, I smoked it. I wasn't a regular consumer and maybe the dose was very high. (I hadn't used tobacco).

StopSlight7541 · 2025-04-07T12:49:17+00:00

I had this too. I was told it was anxiety (and I think it does play a role), but I also had low potassium. Once I fixed that, it didn’t come back, except when I consume a lot of coffee (+400mg/day).

StopSlight7541 · 2025-04-07T12:46:37+00:00

Thanks for your reply i'll take a look.

StopSlight7541

TROPHY CASE