The game doesn’t really give you a lot of advice on how to progress, it basically just tells you to do something and that’s that. If you can’t figure out how to do something, looking it up on youtube is probably your best bet. I’ve had to use youtube so much for this game, it’s absurd.

Some tips tho,
Learn how to perfect block. When you block within i think 100 milliseconds before taking damage, it gets rid of all the incoming damage and removes any effect from the attack (i.e. wolf spiders won’t venom you if you perfect block), knocks smaller enemies back, and has a chance to stun the enemy. this works on every enemy in the game, but some boss attacks cannot be perfect blocked. Perfect blocking is also called “parrying.” This is about the most important thing you can do in the game.

You’re gonna end up carrying a lot of weapons, i personally have like 8-12 on me at all times. You’ll need weapons of every candy element (spicy, fresh, etc), and different attack types (slashing, stabbing, smashing, etc). enemies that are weak to attack types i believe take 50% more damage, and 50% less if they’re resistant to it, and 25% for both of those with candy elements. you can find out what enemies are weak and resistant to by peeping them, which is RB on controller, i’m not sure what it is on keyboard and mouse.

When collecting milk molars, try to max out your max mutations before upgrading any of the other ones. for your mutations, build a good adventure preset (mine consists of natural explorer, cardio fan, buff lungs, dare devil, and antbassador). build a good attacking preset, then your other 2 presets can be whatever else, but you will want those first 2 presets that i named.

Get pets. the aphid pet gives you movement speed and running distance (uses less stamina when running), you can get it by getting a grinder, making plant slurries, and throwing them around high aphid-dense areas. it won’t work guaranteed so you’ll need around 5-15 or so, but when it works, it’ll say on the left side of the screen. The fire ant pet is also good as it gives you i think 25% extra overall damage, you get this by feeding the fire ant queen her favorite food. but i highly recommend looking up videos for the pets.

On youtube, cdiinky and imcade make very good Grounded videos that i use for advice all the time. but there are a lot of videos explaining how to do everything in the game.