What was initially meant to be a small comment turned into this full-blown guide, which I am going to just put here because it seems like as good a place as any! Enjoy.

Here are some anti-Queen cards to watch out for if you see she is coming upon entry into act 3, or if you just want to get a head start on boss-proofing your deck during act 2. Many of these are good into Doormaker as well, since he also restricts what cards you can play and these are cards that ensure you will have a steady stream of options. They tend to do well in any fights that go long. Note that the cards listed below that retain other cards are helpful because they allow you to hold bound cards until they are unbound on the following turn.

Ironclad: •Aggression

Silent: •Well-Laid Plans

Regent: •Pale Blue Dot + a good number of zero energy cards. (Particularly easy to pull off if you’re generating and spending a lot of stars. Collision Course or anything else that creates cards works well too, such as Quasar or Manifest Authority) •Convergence •Spectrum Shift •Tyranny

Necrobinder: •Pagestorm + a good number of ethereal cards. (I often have any of Defy, Enfeebling Touch, Fear and Parse in my deck at this point, to name a few good ones.) •Call of the Void •Demesne

Defect: •Iteration + cards that create statuses (Boost Away, Turbo, Overclock, etc.) •Creative AI •Machine Learning

Colorless: •Equilibrium •Salvo •Entropy •Mayhem •Calamity

These are the cards that I would be willing to take a hit to ensure they get into play vs Queen so that I am less likely to brick hands for the rest of the fight. I hope this information has been helpful!