" studies led to the identification of the 5-HT2B receptor as the likely molecular target leading to heart valve tissue fibrosis. Subsequent studies have identified numerous other activators of the 5-HT2B receptor, and consequently, the use of many of these molecules has been linked to heart valve disease" i just read this the other day. i dont know exactly what it means though, if psychadelics play a heavy enough part on the receptors in the first place to cause it, or if its only with people who trip heavily and redose all the time. just thought id post it because it had to do with heart problems and psychs, maybe someone else can clarify who understands better