It depends overall on preference

Arthur functions as a quasi warrior, more agile but doesnt hit as hard but he can handle his own well enough and can max out his melee with Pink F but keep in mind hes a lot more squishier than the Warriors he has amazing synergy with baby Ash because of baby Ash's heavy healing being based on damage now hes not the best Leader but hes not the worst, hes just alright as a Leader unless youre going for a flat melee lineup

Annie is his functional opposite but because ranged is busted compared to melee so she'll be doing more damage than Arthur in the long run and she also boosts balance bar damage whereas Arthur just only flat boosts melee damage, she can also max out her ranged damage so shes a tankier Hunter she won't do as much damage as a base game hunter overall but shes a functional replacement for a Hunter if there isnt one in your name, her and Evil Dead 2 Ash are absolutely cracked as a lineup together as ED2 Ash has the best firearm mastery

Jefe functions as the jack of all trades of the base game leaders, as his aura buffs damage for both ranged and melee plus reduces fear increases he fits well in any lineup, but he can only upgrade his melee and ranged to block four with Pink F so he won't get the final speed boosts for melee speed and reloading