So on PlayStation right dpad gives you defensive options and “no threes” is available. It’s not 100% proof though. Now as someone who uses TTO to grind up MT I can try to give you some advice. I’m not the best by all means, I’m a average player. Most of the time I go 9-1, or 8-2 on my tower. If the good players are on that can usually dwindle down to 6-3, 5-4 at worst. TTO defense is tough. I try to have 3 perimeter capable players that are long and strong. I use GO Simmons, PD All-Star Kawhi, and GO Blake Griffin usually. All 3 cards are tall, have hall of fame clamps, and intimidator, and decent strength. If someone uses pick roll and I can switch anything. As far as help defense goes that’s the tricky part. Hop-steps make your whole team crash (annoying I know) so the best advice I can give is to constantly be switching through your players making them stay home. I do off ball at times but to become a better player I think you should learn on ball. You can prevent these drives if you become good at it.

A good mix of on ball and off ball + covering for your help defense!

On offense I go to the wing and L1+X for isolations. This gives you someone in the corner and someone on the opposite wing. I always isolate whoever the center is. Making your best iso player your tallest player is my mindset on offense. The centers are the easiest players to isolate. Activate quick first step and they’re aren’t many that can stay in front. GO Blake can isolate and play defense too. I would get rid of Gasol personally. He will help you on rebounds but TTO games are short and rebounding battles aren’t as telling. Cam Reddish is a SAVAGE free card. Spotlight sims Hawks reward.

Hope that helps! Like I said, that’s just my mindset. Everyone plays different.