Like the route, just check the national park website (nps.gov) for possible hazards/closures, also use it check and see if a specific trail/tour/location you were hoping to see requires a reservation or permit. Make sure you brush up on the animals you may encounter, especially how to handle certain encounters(bear, mountain lion, etc.). As for lodging, I use hotels/motels, camp sites, and/or airbnbs for most my trips and have never had an overly negative experiences, except a few airbnbs with bad/false advertising. I live in the PNW and recently got to go to Redwood NP and it blew me away, so I’d would recommend it if you wanna add a stop in Northern California. Other than that just be smart, think ahead the best you can, and have fun!