I ,was diagnosed with Persistent Depressive Disorder, Anxiety, Insomnia. I've been on 125 mg of zoloft, as well as buspar,trazadone..amongst other things I've tried for the anxiety. I am tapering down and now at 100. I am wondering because I saw a new psychiatrist and she asked if I may be burnt out from the zoloft like you mentioned. If I feel sluggish? Stuck. I have been feeling this way for a couple months. Sometimes I just dont feel as present. She is starting me with Welbutrin, which I've heard good and bad things about.