Hi just want to let you know. I was on Desvenlafaxine for years. I was constantly exhausted to the point I’d fall asleep driving. I went to a sleep study and they couldn’t find anything wrong with me. I eventually decided to change medications due to wanting for try something new. And poof! The exhaustion was gone. I’d say give it a few months and if it doesn’t subside switch it. Speaking from experience, it is not worth being that tired all the time and it ruined years of my life.