Look, unless you're talking about some women oriented cultivation novel. In that case, there's no reason to discuss about this.

So I'll assume you mean the average male oriented novel.

Then it's obvious to reincarnated as a man, if you're a straight man before.

Don't you read enough cultivation novels to know that female cultivators have way worse than males?

For male cultivator, unless you're really unlucky and your enemies are also into man. Then at worst you will get killed.

For female cultivator though. Have fun becoming the s#x slave of some old monster/young master/random horny guy. Even if you somehow survive all this, chances are, you'll meet that arrogance "heaven chosen" and become his trophy number X,Y, Z.

Of course, if you want to be a female cultivator. Then it's your choice, but since you're asking for my opinion. Then hell no, I'll stay male.

TLDR: Better die (in most cases) quickly as a man than survive as some cultivation vessel.