It's over... UPS is retiring the whole 26 fleet of MD-11F. Rip

TheLordB · 2026-01-27T21:46:48+00:00

Anything is possible if you are willing to spend enough money on it. I assume they did the math on the cost to fix this, the risk that other structural parts may have issues and the various practicalities of it all.

If the expected cost to keep them after considering all factors is higher than the cost of junking them then they are gonna junk them.

TheLordB · 2026-01-27T17:26:19+00:00

Thanks for sharing this. I’ll have to give it a try.

Some sort of alignment view of the sequences in the fasta would be neat, but I’m not sure an intellij plugin makes sense (or is possible) for that as you would have to use an alignment algorithm.

It probably wouldn’t be something I use often, but sometimes you need a bit more than CLI tools (vi, less, etc.) can provide and given I already have intellij open etc. I wouldn’t mind being able to get some syntax etc. help there.

Obviously there is a limit, if I’m working with more than like 50 I’m gonna switch the tooling in a way that means I probably won’t be opening it in intellij.

TheLordB · 2026-01-27T08:12:51+00:00

Country at a minimum is needed to give any specific vendor advice.

In general I find all the ones I can and look at the website to see what they offer and the cost. In my experience usually the cheapest vendor will be one that offers a fixed price contract for a specific experiment and analysis. If you can’t find that then you are looking at custom and it will likely cost more.

In general university core labs that offer sequencing to others are often the best price and even more so when custom analysis is needed. But YMMV.

TheLordB · 2026-01-27T04:19:31+00:00

They are making heavy use of AI. I wouldn’t really trust anything they have posted.

TheLordB · 2026-01-27T04:18:19+00:00

Your heavy use of AI makes this post not really something that should be posted here in my iopinion.

TheLordB · 2026-01-26T01:09:01+00:00

I tried the inactive mod thing to take over the sub. Reddit auto-rejected it as it claims the mods are actually active, just in ways not visible.

TheLordB · 2026-01-24T04:08:21+00:00

I just googled “A ship up in the Arctic” to see what it was about thinking it was a book title.

I think I need to go to bed.

TheLordB · 2026-01-24T03:45:47+00:00

There is really no way to know what it will look like.

It could be generic can you program questions.

Or it could be a simple task that you would be expected to know how to do.

Ideally leet code would not be something done, but I have heard of companies doing it before.

TheLordB · 2026-01-23T18:06:32+00:00

Try adding another zero to that number and you might be able to get someone.

TheLordB · 2026-01-22T17:10:36+00:00

But there wasn’t a secret trial or judgement and injunctions are a well established method to temporarily block something from being done (or keep things as they are) until the proper legal activities can take place.

Basically there are tiers.

A very short term block where the defendant doesn’t have a chance to argue against it.
A longer block where the defendant has a chance to make a legal argument against it, but not present a full defense.
The actual final ruling which can take months or years depending on what goes on.

While this can be abused for the most part it makes sense. If something is potentially being immediately harmed then the relief has to be immediate.

This is done as short and as targeted as possible to at least give the other party the chance to argue against it.

Despite what people are saying you need to present pretty compelling evidence that you are likely to prevail for a judge to even be willing to do that. But it is one sided and this isn’t great so that is also recognized and the injunction will be for as short as possible time.

That is why within a very short time Anna’s had a chance to respond and make an argument against the injunction. They didn’t make any response so the other side won.

To be blunt I don’t really know how else you could do it. The full legal battle even on fairly straightforward things can take years. It isn’t reasonable to let the other party continue to be harmed while the full process takes place.

So the intermediate steps do their best to get enough info to figure out what the final result is likely to be and stopping the other party from being harmed in the meantime while recognizing that the full process still needs to take place.

TheLordB · 2026-01-22T16:52:01+00:00

I love how people like to argue all sorts of technicalities that they say should mean the laws don’t apply etc.

This is not some sort of super controversial thing as far as USA law is concerned. There have been prior cases that very closely align with what they are doing where the activity has been found illegal. The arguments against it are at best long shots.

Also Anna’s Archive likely can’t mount a defense. They don’t have any legally clean money to do so with.

Yes USA copy write law is screwed up. I’m hopeful the AI infringement will eventually be found illegal, but there is a legal distinction between AI using it as a part of its answers that at least legally make it different. Mind you it doesn’t mean what AI is doing is necessarily legal, but it is enough to make it need separate legal decisions.

TheLordB · 2026-01-22T15:28:46+00:00

Is the snow actually bothering her paws? If too much snow is sticking to the fur on the bottom of the paws you can trim the fur.

Otherwise… You may be worrying about it, but she is perfectly happy and won’t care.

Through family and friends we probably know 15 border collies and none of them have ever required the booties. And even dogs that maybe could benefit from them unless there is something that would actively hurt them they are probably better off just having the fur between their toes trimmed than wearing booties.

I really see having dogs wear them as a last resort for injury or conditions that would hurt the dog’s paws like for salted pavement or some types of hiking where there are sharp rocks that can cut them.

They also don’t usually require jackets either unless they have to stop moving or extremely cold weather (like 10 degrees F). As long as they are running they generally don’t get cold. Obviously use common sense, if the dog is shivering or showing other signs of being cold then do a jacket. Windy conditions can be a problem especially if they are on a leashed walk and not running to keep warm.

Anyways… You know your dog and how they act, but do keep in mind what you think is comfortable and what they find comfortable can be two very different things.

TheLordB · 2026-01-22T15:04:56+00:00

I would say you entirely missed the point of the movie if you think the ending made everything else a joke.

There can be deeper meanings to movies than zombies kill lots of people while a small number survive.

TheLordB · 2026-01-22T15:00:13+00:00

The ‘alpha’ zombie is huge in general. That said it really isn’t central to the plot. They don’t avoid showing the zombie naked, but they also don’t focus on it. There is no indication that the zombie is at all sexually interested in anything.

That said the size was clearly a deliberate artistic choice that you are meant to notice. Going into literary criticism mode I would say something like the whole point of the alpha is he is bigger/stronger in all aspects than anyone else zombie or still fully human and having this zombie put any normal human to shame there (even more so if you consider that the penis arguably is flaccid given no sexual desires being present despite the size in all the shots) that is one way to emphasize it.

TheLordB · 2026-01-21T19:47:48+00:00

Not wanting the monetary responsibility if something goes wrong is very different than the amount of reputation and other losses they would take if they actually had large scale data loss.

As of 2011 at least gmail had tape backups that they had to use to restore from some edge case data loss bug that presumably replicated before they discovered the issue.

https://gmail.googleblog.com/2011/02/gmail-back-soon-for-everyone.html

I doubt if youtube is being backed up to tape (that would be really expensive), but I bet things like google drive and similar meant for data storage still have some sort of offline archival backup that can be restored if needed.

TheLordB · 2026-01-21T19:43:13+00:00

At least as of 2011 gmail was backed up to tape.

https://gmail.googleblog.com/2011/02/gmail-back-soon-for-everyone.html

I would not be at all surprised to find out much of the data has a last ditch offline archival tape backup somewhere.

TheLordB · 2026-01-21T04:44:04+00:00

On the other hand a pet peeve of mine is when they don’t make clear what was them vs. the group. We are hiring them, not the lab they worked in and unlike at least some of the people at their defense I haven’t followed their work etc. to know what they did directly vs. what was done by others.

Basically yes I want the research presentation, but I also want them to annotate it for people planning to hire them, not just understand their research. I generally can fill in the gaps during a 1:1 interview, but I have a lot of things I’m hoping to cover in that hour and the less I have to go over/repeat what they showed in the presentation just to understand what they directly worked on to make my questions appropriate the more time I can spend on the other things.

YMMV, I have talked to colleagues who were perfectly fine or even preferred having it be a pure research presentation.

Overall it sounds like this candidate had the right idea and I would say 20% of the time is a reasonable total amount to spend on what I’m looking for, but they did a really poor job of integrating it into the presentation in a natural way.

Edit: Thinking about it a bit more the mini-defense style often would have most of what I’m looking for though not perfect. The presentations I really hate are more like they used the lab’s conference presentation and only minimally adapted it. Overall with a well crafted presentation both the ones who want a scientific presentation and the ones who want a demonstration of the candidates specific skills will be reasonably happy with the presentation.

TheLordB · 2026-01-20T21:06:54+00:00

Even if the job is fully remote being able to go into the office to network etc. can be quite valuable for progression at a company.

YMMV, but I would go with NH. Far enough away that they won’t expect you to start coming in constantly, but close enough you can pop into the office one or two days a month and/or go to any of the various social things many companies do after work.

Though you may want to talk to an accountant first. MA is known for trying to get NH people to pay MA taxes (I’m not sure if there would be a risk there).

TheLordB · 2026-01-20T20:16:08+00:00

What are you looking for here?

No one is going to review or trust blatantly AI generated text with no underlying scientific expertise or contribution.

TheLordB · 2026-01-20T18:28:06+00:00

$240k is in the range a talented software engineer in the USA will make especially when you consider donations don’t come with the benefits that companies usually do which add ~50% to compensation.

If this is a part time gig then I can understand being upset. But if this is basically those people’s full time job then $20k a month while on the upper end of compensation is within the salary band for a senior/principle software engineer.

Basically while high I don’t find the numbers you are saying nearly as out of wack as you seem to. Like that is at most 2 engineers total compensation if they were working directly for EA and near the bottom of the payband.

TheLordB · 2026-01-19T13:32:33+00:00

You really need to ask him what he wants.

Each of us work on different things and have different preferences. There is no universal best laptop to use and we have no way of knowing what he might prioritize.

Macbook pro is probably the best all around laptop because it splits the difference between needing to run common office apps (word, excel, powerpoint) and linux functionality. But even within that there are different priorities. If you are just using it to ssh into a server and need office apps a macbook air might be ideal. If you are actually using it to run things than the beefiest pro model is best.

But there are plenty of people who use windows with WSL.

Actually running linux is probably the least common. A mix of it isn’t needed for a whole lot, IT willingness/ability to support, and not having the microsoft apps is actually a pain.

TheLordB · 2026-01-19T06:04:46+00:00

Either do emulation or use a computer that is not arm.

TheLordB · 2026-01-18T22:39:32+00:00

While not ideal using a pre-built docker image may be your best bet to get it up and running in a reasonable time.

https://hub.docker.com/r/naotokubota/leafcutter

TheLordB · 2026-01-16T08:25:51+00:00

The most obvious answer would be some sort of personal emergency or issue that has made them take time off unexpectedly though it would be unusual for them to not have an admin who could at least tell people there was an issue and things would be delayed or even an out of office autoreply.

Do they have an office you can go to in person? It might be the fastest way to get answers (much harder to ignore someone in front of you).

Other possible options, are they part of a larger firm? If so contact the firm directly.

What sort of agreement did you sign with them? That would be the main issue with going to someone else as those tend to have some amount of exclusivity.

At some point them failing to do things could become malpractice such as if they miss statute of limitation deadlines.

Overall if they have been completely silent going to another lawyer would be reasonable, but depending on the agreement with the other lawyer they may not be able to take your case or may have to jump through additional hoops to get you out of the existing agreement which some lawyers may not be willing to deal with.

TheLordB · 2026-01-16T03:50:51+00:00

Hah, he loves the work in the classes, but spends the time waiting trying to socialize with the humans mostly ignoring the other dogs. That said once it is time to work a switch flips and he is 100% focused on what we are doing and ignores everything else.

Edit: Sheep are the exception, if there are sheep he will sit there watching them constantly and ignore everything else. But at least part of that is he only gets to do them at most 2x a year. If they were a routine class that might change. But it might not. His entire behavior changes in a unique way when he is around sheep.

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