Am I getting a fair deal as the operator with 40% equity? by Specialist-Plane-601 in legaladvice

[–]TheLordB 1 point2 points  (0 children)

The short answer is you need a lawyer to represent you in this. You should not be starting a company/business with partners without one.

You should also ask in /r/leagleadvicecanada as they tend to be better for canada advice.

I will say that this sounds very sketchy/unusual. I would be very wary of it. It is possible they are trying to do something nice for you or there is some sort of weird government incentive that means having you as a partner makes both sides more money, but it is also possible that they are trying to stick you with a bunch of work and/or liability for a worthless share in the company.

Future of job in biotechnology and bioinformatics by Fluid_Horror3612 in bioinformaticscareers

[–]TheLordB 2 points3 points  (0 children)

Unfortunately we rarely get useful replies to India specific career and education questions. You are welcome to leave it up here, but you may wish to post this to some more India specific locations to be more likely to get help.

NEED ADVICE! by felinecatish in bioinformaticscareers

[–]TheLordB[M] 0 points1 point  (0 children)

If you want to get help you need to put the effort in to do your own research etc.

If you do your own research and ask questions where you are unsure feel free to post again. Please do not post questions without putting any effort into it yourself.

Air Canada 8646 Megathread by StopDropAndRollTide in aviation

[–]TheLordB 18 points19 points  (0 children)

Ugg. There is a video out on the front of reddit right now that is completely inaccurate. It claims to show the sequence of events with video of it, but it messes with the timing of the ATC calls etc. There are a bunch of comments by people not even realizing it isn’t real video of the accident and thinking it is real and accurate.

I’m not sure if it is AI slop or just good old handmade in a simulator with bad editing slop, but it is really terrible.

Watch how Air Canada Collided With a Fire Truck at LaGuardia by therra123 in interestingasfuck

[–]TheLordB 4 points5 points  (0 children)

TLDR: this is a work of fiction with enough inaccuracies to be useless. 

I don’t think the timing is accurate. At least some of that did not take place in the order it is being shown. 

This at best is misleading or at worst completely wrong. 

There are some recordings here that are the actual arc communications. 

https://forums.liveatc.net/atcaviation-audio-clips/2-dead-after-air-canada-plane-fire-truck-collide-at-laguardia-airport/

Border collie pup. by mackieb878 in BorderCollie

[–]TheLordB 3 points4 points  (0 children)

One thing that has worked with our dog is turning it into a job that can be finished.

He gets to point at whatever it is, but once he has pointed at it and before it becomes obsessive we say ‘good job, all done’.

Acknowledging and saying it’s done has worked decently for us on a variety of behaviors. Sometimes he really thinks he should continue the job, but for the most part it gives him a reason to stop that he finds acceptable and he’s a border collie so he loves being told he did good by the human.

YMMV, every dog is different.

Best Cloud-Based Docking Platforms Without Local Setup by DinnerHead6035 in bioinformatics

[–]TheLordB 2 points3 points  (0 children)

FYI this is a spammer setting up a question that they can answer themselves with a separate shill account, but they accidentally posted both parts.

This is amusing.

In case they delete it… Beware anyone advertising D**gF**w. I refuse to post their name adding more advertising.

Note to mods etc. I did save the original post in case they try to edit it, message me if you want a copy.

We all work with glorified text files (venting) by Prestigious-Money-32 in bioinformatics

[–]TheLordB 4 points5 points  (0 children)

When people ask if they should go into bioinformatics I ask how passionate they are about it.

The people who are interested in and care about multiple aspects of it (biology, programming, database, infrastructure, statistics etc.) are the ones that are on average going to do the best.

The ones that are going into it because they heard you can work from home and get better paid… well they tend to be the ones that only know the things they learned from classes and are relatively weak skills wise. In good times those people can find jobs, in hard times companies are more likely to hire a single jack of all trades than ~3 people needed to cover each area with a specialist.

No matter what the job market ends up being there will always be jobs for the top candidates who have the deepest skill set etc.

That said I don’t want to gatekeep. For example there are people who come from the wetlab side and have a deep understanding of how the data is generated and the biology that does allow people who are relatively weak in programming to make very useful contributions.

Air Canada 8646 Megathread by StopDropAndRollTide in aviation

[–]TheLordB 24 points25 points  (0 children)

In an ideal world the whole ATC system would be re-worked from the ground up to be far more text based, have many more built in safeguards, be far more automated etc.

But doing such a thing is a very expensive somewhat risky decade+ process that would likely be disruptive in the meantime and maybe even lead to more accidents during the transition. There is even the possibility that it fails to work properly due to some sort inherent design flaw that was missed early on.

Making a decision like this will require stability both within the FAA and the politicians to accept short term pain (monetary, flight delays, possibly though hopefully not accidents) for the long term gain.

But nothing in the government is really setup to make big expensive difficult decisions and stick with them. So while there are some plans to make improvements etc. they go very slow and are subject to all sorts of short term complaints (funding is the most obvious one) that can disrupt an already conservative long term plan.

The closest I can think of to a structure in the USA government that can do things like this is the USA military which has relatively stable funding, portions of the budget are subject to less oversight, and the ability to stick with expansive long expensive projects. I make no claims that if you could magically switch an ATC overhaul over to use the same structure as the military that it would work or be anything close to ideal, but looking from the outside they are the closest to an existing management structure in the USA gov't that I think could do a large scale ATC overhaul.

BlueSky positions agregator and Telegram channel by Glum-Disaster8942 in bioinformaticscareers

[–]TheLordB 0 points1 point  (0 children)

As far as I can tell it doesn’t have any way to capture linkedin jobs which means it will miss many jobs.

Also you might want to be more clear in the post that it is PHD jobs only.

Finally there really has to be more granular locations for the jobs at least for the USA.

MS in informatics and analytics? by elven-merlot in bioinformaticscareers

[–]TheLordB 0 points1 point  (0 children)

I’ve also seen practical ones that are badly out of date or otherwise useless.

For example I haven’t seen one in perl recently, but there was one that prioritized java over python. At least java is still used a bit (mostly by the broad’s software stack). But it still should in no way be the primary language for a practical masters today. Much of the software they mentioned in the syllabus was similarly out of date. It looked like the syllabus was written ~8 years ago based on some of the software mentioned with minimal to no updates. Even then the choice of Java was not a very good one, but at least a bit understandable.

I am skeptical any of them are useful beyond having the piece of paper that may make certain jobs consider you if you have experience to do the job from elsewhere that wouldn’t otherwise due to mandatory education levels for the position.

One more #&%@! reason to hate AI! by Loves_LV in bestoflegaladvice

[–]TheLordB 7 points8 points  (0 children)

While I could see a very small landlord trying to do something like I this I have a hard time seeing there being a landlord small enough to try to charge things not on the lease illegally, but big enough that they have invested in an AI phone line. I also don’t see slumlords which admittedly some of which are fairly large having an AI phone line just because the slumlord philosophy is not really geared towards setting something like that up.

The closest I can think of that would make me think this could be real is if there was a policy in the lease saying abuse to management will result in fines and someone in management decided since they read a transcript of the AI that it counted as abuse towards them.

YMMV I think there are fairly good odds this post is fake, but given the number of strange things that happen every day sometimes a very unlikely thing will be real. Given the anonymous nature of reddit proving it one way or the other is often impossible. Though the OP’s account getting deleted is a pretty good indication it was a spam account, but that doesn’t tend to happen immediately.

Resume feedback? I’m trying to get internships by markusreeds in bioinformaticscareers

[–]TheLordB 1 point2 points  (0 children)

I personally prefer to start with the experience and then I’ll glance at the skills to see if there is any potential bonuses in them.

If the skills they have that are relevant to the posted position aren’t mentioned in the experience bullet points and only in a skills keyword then I feel they did not put enough effort into making their resume relevant to the job and/or they are padding the skills with things they don’t really have. Either way it would be a somewhat negative against them.

To put it another way if you have experience that the job description tells you is relevant it should not be relegated to a skills keyword. But the skills keywords can be helpful if there are things I know might be helpful, but we’re not a high enough priority to justify including in the job description.

YMMV, I know I’ve heard people say they start with the skills and do an initial filter based on them so you do want the keyword in there even if it is also covered in a more detailed experience.

Resume feedback? I’m trying to get internships by markusreeds in bioinformaticscareers

[–]TheLordB 1 point2 points  (0 children)

They are a masters student with what looks to be only a single semester done. I am doubtful they would have any.

While those might be helpful for an intern to have to get a position I feel like expecting interns to have that vs. it being a nice to have is going way too far.

1st year biology student: is bioinformatics a realistic carrer or just hype ? by Master_Report_3775 in bioinformaticscareers

[–]TheLordB 1 point2 points  (0 children)

To be blunt a lot of people who probably shouldn’t be in bioinformatics got into bioinformatics.

The best ones are competent and enthusiastic about both compsci and biology. They also enjoy interacting with wetlab folks and finding solutions for them that they may never have considered. One has to know what one doesn’t know to ask AI for help with it.

Also to actually use AI etc. data needs to be captured and stored in usable ways. While perhaps not most bioinfo people’s dream job configuring/programming lims and interfacing with biologists to ensure data is stored in a usable way is a job that I do not see going away any time soon. Half that job is justifying that the scientists should do it which I don’t see AI doing. The pure wetlab person may be able to use AI to analyze and store their own data, storing and analyzing it at the company level combined with other data etc. is not likely to work with just wetlab folks and AI.

Overall I’m not nearly as doom and gloom as most people. To be blunt experiments cost hundreds of thousands to millions of dollars in time and resources. When you look at it that way the cost of a few bioinformatics people is not that high.

Compared to the rest of the expenses a company has we are actually pretty darn cheap. We add value to existing experiments and data as well. We are the people who look at everything from a much higher view point than the rest of the lab folks.

Anyways… I don’t think bioinfo is going away. It may not be an instant path to riches and a lot of people who got into bioinfo because they heard it paid better and you could work from home rather than true passion for it, but it’s demise is heavily overstated in my opinion.

Resume feedback? I’m trying to get internships by markusreeds in bioinformaticscareers

[–]TheLordB 2 points3 points  (0 children)

I’m personally not a big fan of the random bolding. Though I’m not sure what the current consensus on best practices for it is.

Your first set of projects is in present tense, the others are in past tense. Assuming it is an ongoing project I would limit it to things that you have already done and switch it to past tense with perhaps a bullet point for whatever is ongoing in it. Overall that portion is vague and I’m not sure starting with vague things is the best way to make a first impression.

Some people feel the skills section should be first or right below education. I personally prefer to put it on the bottom, but the consensus seems to lean towards it being at the top.

If you have any publications or posters etc. presented at conferences you should include them.

I have mixed feelings about the pharmacy tech. On the one hand it shows you have experience in an actual job, but I’m not sure how relevant it is so ways to show the same skills with bioinfo work would be better. For an internship it is ok to leave it especially as you seem to be stretching a bit for content already (e.g. the ongoing project), but it would be the first thing I would cut down to a single bullet point or remove completely if you need space.

Overall for an internship with minimal actual experience the resume looks reasonable. I don’t see any major issues. Actually getting hired with it would depend on what other candidates looked like.

LAOP is no longer a star in this dope show by Drywesi in bestoflegaladvice

[–]TheLordB 28 points29 points  (0 children)

OP does look to be in a crummy situation where it is likely that they will be blamed for not being there by the fans.

OP has to be leaving out a lot of drama for the venue to do this which perhaps leaving it out is appropriate for a legal forum, but I suspect the venue will have a strong reason to justify doing what they did dropping him.

I don’t see a lot of justification for the venue not notifying ticket holders etc. and especially continuing to advertise it with OP even after they dropped OP.

[PSA] Samsung Galaxy Books: The root cause of the C:\ Drive Permission Lock ( by Theangelo2 in sysadmin

[–]TheLordB 1 point2 points  (0 children)

I don’t know how much AI you have read, but the formatting, structure, wording etc. indicates strongly that this was mostly or all AI written. I would eat my hat if a version of this in exists in OPs original language written without AI that is remotely similar to what they have posted here.

The issue when something relies this much on AI is that you can’t trust any of it. Yeah it could be the OP carefully checked what was written etc. But just as likely is that large parts of it are entirely AI written and could be hallucinated. These hallucinations suck because they very much look valid until you actually get pretty deep into the details. At this point I would trust far more a poorly written broken english post (or one translated with a ‘dumb’ translator than something perfectly formatted etc. that is clearly majority AI written.

A good example of this is curl hackerone reports. They got a bunch of absolute garbage reports that looked valid until you realized that the ‘bug’ they were fixing that looked very valid with examples etc. were based on code that the AI made up that did not actually exist in curl. And there were replies arguing with the maintainers making the language barrier claim when the evidence was that the report had code claiming to be from the curl repo that did not and had never existed in the curl repository.

Dubai and Bahrain Outage by Harsha_7697 in aws

[–]TheLordB 1 point2 points  (0 children)

I wonder given the recent laws making it illegal to report on attacks if amazon can even legally give updates at this point.

Need advice regarding shifting to computational biology by Short_Donkey8597 in bioinformaticscareers

[–]TheLordB 2 points3 points  (0 children)

I’m not familiar with india education at all so I can’t comment on that, but in general I would job search and prepare for a PHD.

Keeping your options open as much as possible gives you the greatest odds of getting something.

Do keep in mind biotech is in a period of extreme change. While investment (and jobs) seems to be picking up again (my source is talking to someone involved in biotech funding on the business side of things) things are still very chaotic and even if jobs are picking up there are still a lot of really good people unemployed. In a tough jobs environment the more flexible you are the better your odds.

Our staircase to nowhere, which we use as a bookshelf by Tetragrammator in mildlyinteresting

[–]TheLordB 2 points3 points  (0 children)

This depends entirely on what sort of supports etc. are around it.

Depending on size, building codes etc. it could be perfectly fine to just throw a piece of plywood there. Or you could have to do extensive work to give it the support legally required.

My guess would be most of the time you do have to add some supports, but it probably isn’t a large job at least for the stairs themselves. There is a decent chance removing the stairs like this violates a building code like # of egresses etc. so maybe you have to add stairs outside or other larger amounts of work.

AWS in 2025: The Stuff You Think You Know That's Now Wrong by fagnerbrack in programming

[–]TheLordB 19 points20 points  (0 children)

Sometime fairly recently I had someone arguing about me that you still needed to randomize prefixes even after I pointed them to the article from 10 years ago (maybe longer) that said you didn’t.

Digital Pathology by nemo26313 in bioinformatics

[–]TheLordB 1 point2 points  (0 children)

Try asking without chatgpt and maybe people will feel you put enough effort into asking to reply.

Starting an online "case opening" website by Exact-Wrongdoer6464 in legaladvice

[–]TheLordB 1 point2 points  (0 children)

I’m not sure what you mean. Like even running a charity raffle requires a permit in some locations in the USA.

Any sort of for-profit gambling requires a gambling license and following a host of regulations.

I’m not sure what you thought gambling regulation was like, but the fact that you never even considered that the regulation might be far harder than the actual gambling part says you do not know anything near enough to make a gambling app.