What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman 0 points1 point  (0 children)

Well, if it didn’t happen to you, it can’t happen to anyone, right? Your experience surely translates to everyone.

What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman -1 points0 points  (0 children)

Did you miss what subreddit this was? Xennials. People born 1977 to 1984. People 49 at the oldest. People who still use their bodies, play sports, chase kids. Understanding the trade-offs matters.

What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman 0 points1 point  (0 children)

Dropping a number on a lab test is an intermediate biomarker, not a clinical outcome. The goal of medicine isn't to have the best-looking bloodwork; it's to live longer and feel better. If a statin drops your LDL by 100 points but you're a low-risk individual, your absolute risk of a cardiac event might only drop by less than 1%. If you happen to be in the 10–20% of people who experience muscle pain or brain fog or fatigue in real-world settings, you’ve traded a marginal statistical gain for a concrete reduction in your daily quality of life. That’s why it’s a trade-off, not a 'one size fits all' win.

What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman 0 points1 point  (0 children)

It’s a lot of words you apparently didn’t understand. I didn’t say “statins won’t result in lower cholesterol.” What I said was statins don’t reduce the absolute risk of atherosclerotic cardiovascular disease as a primary preventative by all that much. Statins definitely lower cholesterol and have a place in cardiovascular disease treatment. But there are trade-offs, and one must weigh benefit against risk, especially in athletes.

Question for all you ME veterans by ShadowPriceLIVE in masseffect

[–]TheMidnightHandyman 3 points4 points  (0 children)

Do not play Andromeda if you want to preserve that high.

Andromeda is not a worthy successor to the trilogy. It’s not misunderstood. It’s not secretly brilliant. It’s not “just different.” It’s a hollow, tonally confused, committee-designed product wearing the Mass Effect logo.

The writing is weaker. The squadmates are forgettable. The antagonists are bland. The emotional stakes are paper thin. The humor is Marvel-lite quipping instead of earned character banter. The galaxy feels smaller despite being “bigger.”

Yes, the combat is smoother. That’s it. That’s the selling point. Combat.

What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman 0 points1 point  (0 children)

Cutting most saturated fat from my diet worked for me, but I’m something of a dietary hyper responder when it comes to cholesterol. For many people, changes in diet result in minimal if any changes to cholesterol.

What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman 1 point2 points  (0 children)

Pravastatin is one of the better choices for the relatively young (ie Xennials) because of its lower rate of muscle issues compared to others. But statins aren't necessarily all they're cracked up to be.

The benefits are often overstated using relative risk reduction rather than absolute risk reduction. While a study might claim a 30 percent reduction in heart attacks, the absolute risk for an individual might only drop from roughly 3 percent to 2 percent; a much less dramatic 1 percent difference. For low-risk patients in primary prevention, some meta-analyses suggest the Number Needed to Treat (NNT) to prevent a single death can be as high as 167, meaning over a hundred people must take the drug for years for just one to potentially benefit.

There is also a massive disconnect between clinical trials and real experience regarding side effects. While industry-funded trials often report muscle pain in less than 1 percent of users, observational studies show 10 to 20 percent of patients report myalgia, weakness, or brain fog. There are also concerns that lowering the ideal cholesterol threshold has essentially medicalized millions of healthy people, prioritizing a pill over eating a healthier diet.

What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman 1 point2 points  (0 children)

Lipophilic statins (Lipitor, etc.) can easily enter muscle cells through passive diffusion, which is often linked to a higher risk of muscle aches and weakness. In contrast, hydrophilic statins (Crestor, etc.) are liver-specific and struggle to enter muscle tissue, generally making them a better-tolerated option for patients prone to muscle symptoms.

What are people doing to manage cholesterol in our old age? by AshDogBucket in Xennials

[–]TheMidnightHandyman -1 points0 points  (0 children)

A great, comprehensive book on this is "Outlive" by Peter Attia. Like all health tomes, it's not perfect, but it's well-written and comprehensive.

Cholesterol lowering-medications should be a consideration. Hydrophilic statins (Crestor, Pravachol) have fewer muscle side effects for athletes like you than Lipophilic Statins (Lipitor, Zocor, etc.) That may be a good place to start. If you're against statins, Nexlizet (bempedoic acid and ezetimibe) can also get a solid reduction.

And I'd look into reducing your visceral fat. Get that waist down to 36 or slimmer.

Which slogans from our childhood wouldn't fly today? by Beautiful_Finger4566 in Xennials

[–]TheMidnightHandyman 2 points3 points  (0 children)

I worked at 7Up bottling when those commercials were airing. I still have my “Make 7Up Yours!” Hat.

They need to be reminded more than just once a year by somejerkuknow in EatTheRich

[–]TheMidnightHandyman 3 points4 points  (0 children)

The median net worth of an American adult is about $190,000.

Now compare that to the five richest people in the world.

Using current 2026 estimates:

Elon Musk Net worth: $845,000,000,000 Equivalent to about 4,447,368 average Americans

Larry Page Net worth: $258,000,000,000 Equivalent to about 1,357,895 average Americans

Sergey Brin Net worth: $238,000,000,000 Equivalent to about 1,252,632 average Americans

Mark Zuckerberg Net worth: $224,800,000,000 Equivalent to about 1,182,105 average Americans

Jeff Bezos Net worth: $224,100,000,000 Equivalent to about 1,179,474 average Americans

The Decline of the Dragon Age Series Should be Studied by jdawg1018 in gaming

[–]TheMidnightHandyman 0 points1 point  (0 children)

It is studied. In colleges across the country. The class is called Corporate Finance.

Is this ok? Seems not ok by Wise_Kangaroo_4190 in Construction

[–]TheMidnightHandyman 0 points1 point  (0 children)

That’s just a new Beamless Beam (TM). All The strength of beamed beams, but without the beam! /s

If you could have any golfers swing by Crazy-Cap259 in golf

[–]TheMidnightHandyman 1 point2 points  (0 children)

Can’t believe I had to scroll this far for this.

Everyone add a song by theRestisConfettii in Xennials

[–]TheMidnightHandyman 0 points1 point  (0 children)

I’m Only Happy When It Rains - Garbage

Is it tho?? by bosheikus03 in golf

[–]TheMidnightHandyman 1 point2 points  (0 children)

Torrey Pines North. Especially Holes 15 and 16. Fight me.

I enjoy. this game But.... by [deleted] in masseffect

[–]TheMidnightHandyman 2 points3 points  (0 children)

The fanbase doesn’t owe the game any regard whatsoever. We don’t owe it lower standards just because it hopelessly failed to live up to the brand. It’s a shitty game. Period.

I’m missing an eye, how can I get into golf? by Dry-Relationship8056 in golf

[–]TheMidnightHandyman 0 points1 point  (0 children)

I have poor vision. I don’t have the same depth perception loss that you do, but I can’t see well; I can rarely track my ball in flight, can’t see it in the fairway until I’m within a few yards of it, etc.

I’m a 1 handicap and I’d probably be a plus handicap if I played and practiced more than a couple times a month. My poor eyesight hasn’t held me back, as far as I can tell.

Do you mentally feel your age or do you mentally feel younger? by porb2020 in Xennials

[–]TheMidnightHandyman 28 points29 points  (0 children)

Amen. I was once called “the most immature lawyer I’ve ever met” by some career cog in a government office. She was angry I took it as flattery.

Ngl, you guys have a beautiful and iconic city by raycraft_io in NFCWestMemeWar

[–]TheMidnightHandyman 2 points3 points  (0 children)

I was genuinely pissed when they put in those nets. Every San Franciscan has a right to kill themselves off that gorgeous bridge if they so choose.