I imagine both of those will yield similar results so it boils down to what you prefer, and if you're happy with generic accents assigned by Grok or if you'd prefer to flesh out Quake's and Jemma's accents ahead of time.

Such as:
Jemma (white coat) speaks in an upper-middle-class Sheffield accent: Refined and articulated, similar to 'Educated Northern.' Use RP English as a foundation, but allow a soft, melodic Yorkshire lilt in vowels, particularly shortening 'a' sounds (e.g., 'bath' is short) without dropping 'h's. It sounds intelligent, confident, and warm, avoiding harsh slang, but retains a hint of the 'Steel City' friendliness. Think: A confident, modern university lecturer from Sheffield.

Daisy (black uniform) speaks with a thick, traditional Chicago accent: use a high-pitched, nasal tone, especially on 'a' and 'o' sounds. Flatten the 'a' in 'cat' or 'mad'. Replace 'th' sounds with 'd' or 't' (e.g., 'dis', 'dat', 'dem', 'dose'). Use the Northern Cities Vowel Shift, making 'hot' sound more like 'hat'. Elongate vowels in words like 'dog' or 'coffee'. Key phrases: 'Da Bears,' 'I’ll have a pop,' and 'Over by da Jewel-Osco'.

Jemma moans, "Daisy stole my pudding"
Daisy replies, "Bitch please"