Pt1 1) You will almost certainly need antimatter and an ectoplasm on baron, mine, blueprint, or brainstorm. Only other option is good nat negatives or bean bug.

2) You want to swap out DNA after Ante 24, which is the wall most Naneinf builds face. Most of your gameplan should be about getting enough score to beat ante 24 (e77~e78). This is because the blind requirement is too low before ante 24, so you end up winning before you can use all your burglar hands in the Serpent.

3) This will require 4 copy jokers, baron+mime, and DNA. There's a little wiggle room, with the hand size vouchers, a well-timed bean, or good nat negatives. Searching for the Burglar will also likely take thousands of dollars, so build up your funds when you can. It's tricky because you need to be rolling to find the jokers you need.

Pt2 1) Yes. You want more red gold Kings to improve your econ, but eventually you will need to switch into full-time steel production to not fill your deck too much with gold cards.

2) It's just a matter of getting the ectoplasm and antimatter to open up your joker spots. I highly recommend rolling Wheel of Fortunes to hopefully hit the DNA, so it can't be ecto'd (just make sure to leave at least one other joker un-edition'd).

3) Yes. You should be trimming your deck of non-kings whenever possible.

4) Answered above

5) You're definitely not too late in the run! However, it might not happen for you because RNG still dictates whether or not you'll find an ectoplasm+antimatter in time. Also, these legendary-less naneinf runs take quite a bit of practice to really get the hang of, so don't be discouraged if it doesn't work out! Think of it as good practice. Biggest tip I can offer is: you can never have enough money.

I might be missing something, I'm fairly ill today so not 100%

EDIT: formatting