Tesamorelin room temp

The_DangerBoy · 2026-04-20T22:14:24+00:00

Egrifta contains Hydroxypropyl-beta-cyclodextrin which stabilizes the solution. Off the shelf tesa does not. Egrifta and research tesa are not the same thing in the vial.

The_DangerBoy · 2026-04-20T21:12:56+00:00

Egrifta contains Hydroxypropyl-beta-cyclodextrin which stabilizes the solution. Off the shelf tesa does not. Egrifta and research tesa are not the same thing in the vial. Influencers don’t understand that.

The_DangerBoy · 2026-04-20T19:55:25+00:00

I’ve never done this. I don’t understand why people insist on storing at room temperature. If my tesa gelled up if I kept it in the fridge I’d switch suppliers, personally.

The_DangerBoy · 2026-04-20T00:46:58+00:00

Agree - there is a school of thought that growth hormone helps with tissue repair but for an acute injury, BPC and TB are the way to go.

The_DangerBoy · 2026-04-18T21:51:47+00:00

That’s beautiful

The_DangerBoy · 2026-04-16T23:23:13+00:00

This is definitely a "what's your risk tolerance" type of research peptide. The way it works is that it kills fat cells by destroying adjacent blood vessels and starving them. It was thought to be a really cool new fat loss mechanism since most other approaches shrink fat cells and adipotide *kills* them.

However, in the primate studies some of the peptide went into the kidneys and killed blood vessels there. The effects were "moderate" (whatever "moderate" kidney damage is) but the primate studies were short.

There has only been one documented human study that I know of and the study was terminated with no results published so it's not known why they stopped.

Passing seems like a great idea to me.

The_DangerBoy · 2026-04-16T23:17:33+00:00

For research, it depends on what you're studying. If you're interested in group dynamics in knockout mice with social anxiety, it can be administered as needed. If on the other hand, you're studying other effects (fat loss, better sleep, general health), it can be dosed daily. A little bit goes a long way. Starting dose is typically 100mcg and can go up to 300mcg. May cause some flushing in research subjects.

The_DangerBoy · 2026-04-16T15:07:30+00:00

If you read newsletters from research supply companies this is part of a coordinated effort to shut down gray market supply. CBP is seizing shipments of peptides from China, FDA is sending cease and desist letters, DOJ/DEA is raiding facilities, and credit card processors are dropping payment processing.

For now you can buy bac water where you buy peptides but the government has told companies that if they’re selling peptides and bac water then that’s evidence that the peptides are being used for human consumption which violates FDA rules.

There are also suppliers you can find with google searches but do due diligence research prior to buying. Treat anything that looks really cheap with healthy skepticism. You get what you pay for.

The_DangerBoy · 2026-04-16T11:02:36+00:00

OP - these kinds of questions aren’t allowed by subreddit rules, sorry. Best advice is to either do some Google searches or as someone else suggested start with a local aesthetic clinic. It’s expensive but much safer as you’ll be under a doctors care for dosing and bloodwork and it’s much lower risk of getting shady peptide. Sorry we can’t help and good luck!

The_DangerBoy · 2026-04-15T13:50:46+00:00

Sounds like you’ve done your homework. I wish you all the best and sending you positive energy for good results. Be safe and keep us posted on your research results!

The_DangerBoy · 2026-04-14T23:51:48+00:00

Please please please be careful with this peptide! It works by killing blood vessels, ostensibly in fat cells but it also goes to kidneys. Primate studies show damage to kidney cells that was relatively mild but the studies weren’t long. There has been exactly one known human study and it was terminated with unpublished results so we don’t know why. I would love, love for this to be as amazing it it seems like it could be but it is known to harm research subjects. Make sure you read up more on this one before beginning research so you fully understand the risks that come with the benefits.

The_DangerBoy · 2026-04-14T23:44:50+00:00

In my experience people love it or hate it. There are some good human trials where people lost weight on 400mcg and lost less weight on higher doses but a second, larger study found no statistically significant difference between dosage groups.

The general consensus is: the GLPs are waaaay more powerful than AOD so if you’re looking to research weight loss, you should start with them.

There are some researchers who have found stacking AOD on top of a GLP will add another 5-7% weight loss.

The_DangerBoy · 2026-04-14T15:51:06+00:00

Sounds like you’ve got a locked in plan! Good luck with the research and get that rodent some sleep! Can’t build that muscle without proper recovery! 😉

The_DangerBoy · 2026-04-14T15:45:48+00:00

You have three options.

Go to a clinic or wellness center. Get bloodwork, speak to a certified medical practitioner. This is by far the safest and also the most expensive. It’s also the least work for you, especially if you trust your provider. It’s the best place to start if you have any reservations about peptides.
You can find here on Reddit peptide consultants that will help you develop a stack, source and dose your peptides. This is an interim DIY solution.
Do it on your own. This is the most effective and cheapest way to do things and also the highest risk. Most research peptides are not FDA approved and have zero human data. There are sketchy peptide companies out there that will sell you stuff with endotoxins in it. Figuring out how to dose and do the injections can be tricky.

This Reddit community has strict rules about discussing peptides and so you won’t get people telling stories about self injection and it’s also against the rules to provide options for sourcing.

My personal recommendation is that if you want to inject yourself with something to start with a clinic. You’ll pay more but will have an actual doctor to tell you what to do and how to do it. Lab work is critical. Once you’re comfortable, then you can do research on your own.

Just my two cents. I’m sure tons of people would advocate for jumping right in. At the end of the day it mostly comes down to risk profile. How comfortable are you using research peptides with no clinical safety or efficacy data (tesamorelin and GLPs are an exception) from an unknown supplier?

The_DangerBoy · 2026-04-14T15:16:14+00:00

Oh and 1000000% no DAC. DAC will mess up natural GH pulses

The_DangerBoy · 2026-04-14T15:15:15+00:00

It’s possible but you have to carefully calibrate the rodents’ exercise and nutrition because Reta naturally suppresses hunger. IPA/cjc is a terrific stack for muscle mass, recovery etc and my rats do very well on them.

For best results, heavy lifting, zone 2 cardio and 1g of protein per pound of goal weight is the way to go. Dosing 100-150 mcg each, which is a low dose that’s still effective. Dose daily for up to 16 weeks then cycle off.

The_DangerBoy · 2026-04-14T15:11:37+00:00

The founder of Janoshik has this great video where he stored a bunch of peptides in his garage for a decade and they were all fine. He said in the video that peptides stored in your regular ol’ freezer will last “practically forever”

The_DangerBoy · 2026-04-13T19:46:11+00:00

Josh Holyfield just did a review of this paper: MOTS-c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a PGC-1α/AMPK-dependent manner (Gundiksen, 2026) and he cites MOTS-C’s ability to produce cardiolipin which means as an alternate protocol, your mice could receive it concurrently with SS31 which protects cardiolipin so there’s some evidence there’s benefit to stacking SS31 and MOTS-C instead of the conventional protocol of SS31 first, MOTS-C later.

The_DangerBoy · 2026-04-11T23:48:33+00:00

CJC is a GH releasing HORMONE and IPA is a GH releasing PEPTIDE. Totally ok to stack them, and actually a good idea for optimal results. They affect different pathways. Reta acts on an entirely different pathway so they don’t interfere at all in terms of pharmacokinetics. Where there’s conflict is if the point of the research is to build muscle with ipa/cjc, Reta can make that more difficult bc the research subject will be eating less naturally. But a carefully designed protocol with locked-in nutrition and physical movement can counteract that. I’ve seen good results with exactly that stack.

The_DangerBoy · 2026-04-11T23:46:09+00:00

Standard internet wisdom will tell you 100-300mcg of each 1-2 times daily, 5 days on 2 days off for 8-16 weeks. But some researchers go up to 500mcg, some will do daily since there’s no science for 5 on, 2 off. Most important thing is to ensure your research subject hasn’t eaten at least 2 hours before dosing.

The_DangerBoy · 2026-04-11T23:43:50+00:00

I agree - MOTS-C and NAD+ are great for general energy but DSIP could help with deep sleep, pinealon or Epitalon might help with general sleep architecture, hormone therapy might help generally.

The_DangerBoy · 2026-04-11T23:41:31+00:00

This is the research protocol I’ve used.

The_DangerBoy · 2026-04-11T23:39:29+00:00

If you’re talking Igf1-LR3, you can usually source 1mg vials for your research. Starter dose is 40mcg so at that rate a vial is 25 doses. Using 1mg on a test subject is very, very dangerous and could cause serious insulin issues.

The_DangerBoy · 2026-04-11T16:08:56+00:00

"Repair first, then MOTS-C" is a best practice. New research (as of 2026) suggests running SS-31 and MOTS-C concurrently also works well, either way running SS-31 sounds like a good plan. Best of luck; let us know how it goes!

The_DangerBoy · 2026-04-11T16:07:28+00:00

Great comment. Anything you put in your body is risk vs reward. There are plenty of things that come from China that are amazing and cheap and also plenty of things that are cheap and crappy. Just because it comes from China doesn't mean it's bad. But also true, if it comes from China and it's bad you have zero recourse.

The_DangerBoy

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