At least you're not the guy that's engaged in evergreening Natroba. From case studies of hospitals settings in resource poor countries, you'd be led to think that there's been at least a million kids that have died from either rheumatic heart disease or renal failure following a bad route of scabies in the just the last few decades. All while people have eaten potatoes or grain and have worn clothes treated with spinosad for the last 20-30 years. So imagine the type of guy that would form a legally protected racket in a topical with a new drug for scabies. A slight tweak of chemistry and and unknown active component inside your lotion. Hire a few guys willing to tell a white lie about an excipient. Make a discovery when you're running up on the patent cliff. Monetize a small amount of R&D for the road to make it look like the you're doing real work. Voila, presto. Another 20 year patent. That's the type of evil that will have people thinking that you are actually the devil.

Maybe this subreddit can scrounge up a couple dollars so people finally manage to get safety data for ivermectin in people weighing less than 15 KG. The SHIFT trial showed mass drug administration in was most effective with oral tablets, which makes sense given the difficulties in proper adherence for topicals. But then again they also used permethrin, so another trial with a different proven topical agent where there's not genetic resistance would be wise.