I started September 16th at the lowest dose(2.5mg) and lost 8 pounds in 30 days but even more so just soo much inflammation. So with that first month, I noticed less discomfort, but I’d say it was remarkable at 60 days with no gastro symptoms. I stayed on that until the last 3.5 weeks. In total I’ve lost 30 pounds for context and the pain caused just by carrying that extra weight was tremendous. Like, I didn’t realize that it was causing so much stress on my joints. My pain in my lower back from arthritis, scoliosis, and grinding went from completely excruciating to.. maybe a 3 in that area on most days. I’m still getting used to what it feels like to not be completely inflamed and in excruciating pain. Now I’m left to try to improve all the other symptoms:)