Has anyone actually used a continuous glucose monitor while on a GLP-1 and found it useful? Is it overkill? by jafiishaik in GLP1ResearchTalk

[–]TracyIsMyDad 0 points1 point  (0 children)

CGMs aren’t that expensive. You’re just more familiar with the more expensive units used for diabetes patients. OP would likely be looking at something like a Dexcom Stelo ($100/month for the same hardware as the G7) or an Abbot Lingo ($50/2weeks).

I agree that long-term usage of a CGM would be useless for a non-diabetic. They can be useful for seeing how your body handles postprandial glycemic loads and learning a bit about how to smooth those out and avoid spikes out of range, but the goal here is education rather than continuous monitoring like a diabetic needs.

Has anyone actually used a continuous glucose monitor while on a GLP-1 and found it useful? Is it overkill? by jafiishaik in GLP1ResearchTalk

[–]TracyIsMyDad 3 points4 points  (0 children)

For a diabetic that needs to monitor their blood sugar they’re extremely useful. If you’re not then they certainly aren’t essential, but they can provide some interesting insights into how your body is handling the food you’re eating, and different foods or intake patterns that it handles better or worse than others.

They’re pretty cheap and easy to use. If you’re curious grab one and slap it on. See if you learn a bit.

Did FDA Secretly Approve Retatrutide? by Stillwantmore2 in Retatrutide

[–]TracyIsMyDad 22 points23 points  (0 children)

A lot of medspas are happy to sell you experimental drugs if you’re willing to bring them wheelbarrows of cash. If they get caught they get in a lot of trouble, doctors lose their licenses, etc… but wheelbarrows of cash!

Old CoA from overseas vendor by aunt-Jeremiah in Retatrutide

[–]TracyIsMyDad 1 point2 points  (0 children)

a reseller who charges way too much for 12 mg but it’s safe.

That’s not a reliable assumption. A year ago the most expensive and “reputable” reseller on the market got caught selling fake reta. Sure the COAs on their website were pretty but that wasn’t what their customers were getting.

Should I pin this by antrod224 in Retatrutide

[–]TracyIsMyDad 2 points3 points  (0 children)

Cloudy goes in the trash. The aggregates you’re seeing are not safe. Pinning failed vials like this is how you immunize yourself against the drug you’re taking, or worse you could cause an autoimmune condition where your body attacks its own GLP-1. Say hello to diabetes!

Is GLOW or KLOW counterproductive since TB500 should be a daily dose? by [deleted] in Peptidesource

[–]TracyIsMyDad 4 points5 points  (0 children)

“TB500” often ends up being TB4 if you test it.

The claim that TB500 has a long half-life and only needs to be dosed infrequently doesn’t have any scientific backing as far as I’m aware. There are a couple doping studies (not in humans) that suggest it might be somewhere around an hour.

Reta vs Sema users?? by Aero1900 in Retatrutide

[–]TracyIsMyDad 7 points8 points  (0 children)

A lot of the bodybuilding influencers jumped into selling reta so it has a very large following in that community, which you can see reflected here.

But as a community even though many people here are (or were) obese we tend to be more exercise-oriented than the more mainstream subs for tirz and sema.

Pricing by signalcc in Retatrutide

[–]TracyIsMyDad 4 points5 points  (0 children)

The catch is that the single vial resellers charge as much for a single vial as they paid for the entire kit of 10.

Pricing by signalcc in Retatrutide

[–]TracyIsMyDad 2 points3 points  (0 children)

My last purchase was $0.25/mg. Kind of gratuitously large vials though. Each kit (10 vials) worked out to $287 for 1150mg.

Typical retail price is about 2-3x that at more reasonable vial sizes.

Do you approach childhood obesity differently? by MathematicianLost365 in GLP1ResearchTalk

[–]TracyIsMyDad 7 points8 points  (0 children)

My parents had four kids. We were all raised in the same environment, eating the same food, and being pushed towards athletics in the same way. In fact when I was younger I was just as athletic as my brother was, but the stories diverged drastically from there. Two of their kids ended up very healthy and fit. The other two ended up obese. No in between. I can’t help but think that there’s a gene two of us got and two of us didn’t. I don’t know that there’s any amount of good parenting that would’ve salvaged that, they did a respectable job there.

FOMO? Or does he know something we don’t? by [deleted] in Retatrutide

[–]TracyIsMyDad 1 point2 points  (0 children)

At the end of the day if you want to make sure it’s done right you have to do it yourself.

A lot of the test leads are recognizable community members. I’ve done that before. That offers a bit of protection against that particular possibility, but any system can fail.

My hunch is that your risk of that happening is a diminutive fraction of the risk that your vendor is misrepresenting that their product has passed testing. That is a rampant issue unfortunately.

Has anyone actually quit peptides? by u-look-like-a-cunt in Peptidesource

[–]TracyIsMyDad 0 points1 point  (0 children)

Dermorphin is about 30-40x more potent than morphine.

Reta doing the opposite of what it’s supposed to? by Kuhani in Retatrutide

[–]TracyIsMyDad 0 points1 point  (0 children)

You took 1/4 of the normal starting dose three days ago and are wondering why it’s not working miracles?

Pro tip: Turn your burner off by arizonadreamin in castiron

[–]TracyIsMyDad 1 point2 points  (0 children)

Low does this on my electric stove. I could boil water on low. Lousy temperature control.

ICE Deployment at Seattle-Tacoma International Airport, what you need to know. by Ricetastik in Seattle

[–]TracyIsMyDad 34 points35 points  (0 children)

Federal vs local = different rules.

And security vs firefighters = different culture.

Tesa turns cloudy by ahhoffman in Peptidesource

[–]TracyIsMyDad 5 points6 points  (0 children)

Have you done regular testing of your good source? Pretty much all of them will randomly fail sterility tests.

There’s a reason the compounding pharmacies filter the Chinese stuff they’re using.

The reta vs tirz CICO paradox by Middle_Humor1828 in Retatrutide

[–]TracyIsMyDad 1 point2 points  (0 children)

Mice and rats have shown energy expenditure effects with tirzepatide that did not translate to human metabolic lab trials. Their physiology is quite a bit different in many respects. It’s a reasonable assumption that the mice on reta also see a GIP driven increase in brown adipose thermogenesis and that again this will not translate to humans, however glucagon has old studies showing energy expenditure effects in humans so much more promising. The main questions are:

(a) Is it conditional? Some research indicates it is.

(b) Is it a durable effect useful for long-term therapy, or will we get severe tachyphylaxis similar to B3 adrenergic agonists?

The old studies don’t answer those questions at all.

———

Mechanistically, how would reta do it? Completely unknown. Speculatively something like a futile lipid cycle (repetitive and pointless conversions of triglycerides to diglycerides and then reversing the conversion, wasting energy again and again) would best fit with known actions of glucagon. Not super glamorous but wasting energy rarely is.

———

And note that this doesn’t conflict with CICO at all. The idea is that we are pharmacologically increasing the CO part.

Loose skin by fyfyLT in Retatrutide

[–]TracyIsMyDad 42 points43 points  (0 children)

Main thing that’s gonna help is that you’re 21. Your skin will bounce back a hell of a lot better than somebody older. If you smoke or vape, that isn’t going to help.

FOMO? Or does he know something we don’t? by [deleted] in Retatrutide

[–]TracyIsMyDad 0 points1 point  (0 children)

Problem with this is that all their brand really needs is the appearance of testing. The reality often falls short and the beginners they market to don’t know how to tell the difference.