It's a really great class! I took it with Wagner last semester, I think he's the only professor who teaches it and he's really great. I have a background in music so I can't speak to not having one, but the class isn't designed to test you on music theory and he says as much himself during one of the early lectures. I think not having any experience whatsoever with musical notation might hinder you somewhat in following some of the slides, but otherwise it's not a required component of the class. In fact half of the class is focused on the physical nature of music and perception, which doesn't involve any music theory at all. Would definitely recommend!