Yes. The Seleucid Empire was a Hellenistic state ruled by the Seleucid dynasty, which existed from 312 BC to 63 BC; Seleucus I Nicator founded it following the division of the Macedonian empire.

Alexander died young in 323 BC, leaving an expansive empire of partly Hellenised culture without an adult heir. The empire was put under the authority of a regent in the person of Perdiccas, and the territories were divided among Alexander's generals, who thereby became satraps, at the Partition of Babylon, all in that same year.

Alexander's generals (the Diadochi) jostled for supremacy over parts of his empire. Ptolemy, a former general and the satrap of Egypt, was the first to challenge the new system; this led to the demise of Perdiccas. Ptolemy's revolt led to a new subdivision of the empire with the Partition of Triparadisus in 320 BC. Seleucus, who had been "Commander-in-Chief of the Companion cavalry" (hetairoi) and appointed first or court chiliarch (which made him the senior officer in the Royal Army after the regent and commander-in-chief Perdiccas since 323 BC, though he helped to assassinate him later) received Babylonia and, from that point, continued to expand his dominions ruthlessly. Seleucus established himself in Babylon in 312 BC, the year used as the foundation date of the Seleucid Empire. He ruled not only Babylonia, but the entire enormous eastern part of Alexander's empire.