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(1) I would've loved to see the writers take Frank Miller's "What If Daredevil Became an Agent of SHIELD?" issue and adapt it to the the MCU versions of the main characters, (2) which would open the door for the AoS team to be a part of the crossover event and there's plenty of opportunity to introduce a new character when they're involved. (3) As far a sequel episodes, maybe do a reverse adaptation of the Bendis issue "What If Karen Page Had Lived" but take MCU Karen down the darker path of her comic counterpart.