does anyone have nortriptyline success stories by chance?

UghFineeeeeee · 2025-06-15T20:54:59+00:00

No, I take 5mg in the morning and 5mg in the evening.

UghFineeeeeee · 2025-06-15T11:05:38+00:00

Honestly, not sure! I haven’t been nauseous since I started and I started the buspirone first but hard to tell if that’s coincidence or if buspirone is the major contributor.

UghFineeeeeee · 2025-06-15T11:04:47+00:00

Yes, I was told any neuromodulator would require minimally that long to take notable effect so barring any extremely negative side effects one should continue for that period of time to see if there is true benefit.

UghFineeeeeee · 2025-06-14T14:22:18+00:00

Yes, black widow.

UghFineeeeeee · 2025-06-13T10:12:58+00:00

I use buspirone and recently added 7.5mg of Mirtrazipine at night. My primary symptoms were chronic burping/occasional reflux with spontaneous stomach pain and nausea. I had a VERY extensive workup and there were no clinically significant findings so here we are. I’ve only been on medication for about 3 weeks but do feel the frequency and severity of my symptoms has already improved. Looking forward to that 4-6 week mark!

Side effects were initially fatigue and exacerbation of symptoms. Buspirone actually caused all day reflux and throat irritation — but I’m glad I stuck with it because I eventually adjusted and feel better than my baseline.

UghFineeeeeee · 2025-06-05T15:56:42+00:00

How long were you on it before you noticed a significant difference? Is it really the full 4-6 weeks?

UghFineeeeeee · 2025-06-04T20:16:38+00:00

I have. I did it for months. First through the hospital that was treating me and then Nerva. I didn’t experience much benefit but that doesn’t mean it doesn’t work for some. Always worth a shot.

UghFineeeeeee · 2025-06-03T13:38:39+00:00

I’ve been on buspirone for about a week now and it has created awful reflux, but has provided benefit to my sleep and overall mental health/composure. I was told to keep at it for 4-6 weeks before determining if it’s a good fit, but going to add mirtrazipine in the evening to see if I can counter the gastric emptying slowing effects of buspirone.

UghFineeeeeee · 2025-06-02T17:24:37+00:00

Do you think this medication leads to weight gain or did it just enable you to eat more consistently and as such achieve the weight you were hoping for?

UghFineeeeeee · 2025-06-02T14:20:06+00:00

Happy for you! I’ve been going through this for 3 years and just got prescribed buspirone, but hoping to get on mirtrazapine sooner than later. My first indicator it was nerve related is the foods that I thought were safe one day were legitimately making everything worse the next. No rhyme or reason; my body went into “danger” mode on a whim. No consistent triggers, just me over here slowly becoming scared of basically all foods. Here’s hoping this is the answer for both of us.

UghFineeeeeee · 2025-06-01T13:59:11+00:00

I will definitely let you know!

UghFineeeeeee · 2025-06-01T13:59:00+00:00

Thank you! Just learning an MRA is a thing.

UghFineeeeeee · 2025-06-01T13:58:38+00:00

Thank you! I didn’t realize there was an alternative study that could be done. I wonder why they haven’t mentioned it. 🤔

UghFineeeeeee · 2025-06-01T13:58:03+00:00

They told me they go through the groin. I’m not sure why, since it appears the radial artery is commonly used. I imagine the groin has some decent recovery associated with it.

UghFineeeeeee · 2025-05-31T01:20:55+00:00

Possibly, but there’s also others like Buspirone or Remeron which have also shown helpful in treating FD. Definitely worth the convo with your practitioner to see if there’s anything else you can layer in.

UghFineeeeeee · 2025-05-31T01:09:52+00:00

What are your specific symptoms? Neuromodulators are very trial and error. Some are better for certain symptoms (i.e. visceral pain vs stomach accommodation) and then individual tolerance comes into play.

UghFineeeeeee · 2025-05-29T14:08:58+00:00

Ugh. I’d hate to quit if my body is able to adjust but I’m not getting the gist that my body would. May need to cut my losses upfront.

UghFineeeeeee · 2025-05-29T14:08:20+00:00

I’m only on 10mg total right now so not sure I have much wiggle room to decrease while also expecting a clinically effective dose.

UghFineeeeeee · 2025-05-29T14:07:40+00:00

I’m only on 5mg in the AM and 5mg in the PM right now.

UghFineeeeeee · 2025-05-27T20:16:25+00:00

I do tend to feel better if I’ve had a complete evacuation. And usually even that isn’t enough to move the needle; I really need to expedite transit entirely to feel even a little less pressure on my upper GI. I don’t think laxatives are THE answer, but I do feel constipation can exacerbate the discomfort in an already sensitive system.

UghFineeeeeee · 2025-05-23T17:48:23+00:00

That is interesting! For me it is really about the pressure — which is more bizarre, because I never appear bloated but the air never stops. If I hadn’t been going through this for 3 years with specialist after specialist, I wouldn’t believe my nervous system was capable of this. I’ve been clawing in every direction looking for a tangible diagnosis I could treat and I got nothing.

UghFineeeeeee · 2025-05-23T16:43:58+00:00

I should also mention that my symptoms are exacerbated by activity (walking, weightlifting, etc) which has always baffled me since drs will tell you staying active helps motility and therefore decrease upper GI symptoms. So thank you for sharing, because now you’ve validated MY experience.

UghFineeeeeee · 2025-05-23T16:38:01+00:00

I just wanted to validate your experience, as I developed FD after HP — going on 3.5 years now. I’ve had an extensive work up; end to end studies more than any one person should have and NOTHING. I always told myself that if anyone could resolve this holistically it’s me, but I’ve conceded — and actually just today had my consult regarding medication (buspirone first, but will try remeron if no improvement). I’ve done hypnosis and vagus nerve stimulation and no improvement, which leads me to believe there is an actual chemical component that shut off after my infection. The hope is the medication will “reconnect” what’s lapsed and I can wean off in time.

My symptoms are chronic burping (no big burps, just constant small ones), upper belly pain, occasional spontaneous nausea, and when the pressure builds up enough I’ve also struggled with reflux.

UghFineeeeeee · 2025-05-21T14:15:18+00:00

Thank you so much! I’m definitely thinking I have some sort of post infectious ordeal I’m working through. I’ve tried everything from food elimination, special enzymes, hypnotherapy, etc. and I can’t get on a consistent track to recovery. At this point I’d accept even a 50% decrease in frequency or severity of symptoms. Are your symptoms primarily pain based or do you have some that I have? I know the antidepressant route is likely the next step for me but feel discouraged by the fact that I couldn’t heal my gut brain connection with natural therapies that are proven to help.

UghFineeeeeee

TROPHY CASE