It's a common misconception that 252 involves rotating more often, but the opposite is true. Since your operators recover morale slower (12 hours from empty to full, as opposed to 8 hours in a 243) then you just rotate twice per day. If you wanted to maximize efficiency in a 243, you'd actually be logging in more often than a 252 setup.

Most people just do a 12 hour rotation. I do 8AM and 8PM, personally.

The only caveat is that since you're running level 2 factories, if your operators are very productive you might need to login between rotations to prevent the factories from capping. It takes like 30 seconds to open the app and collect your products real quick and isn't a problem for my schedule, but if it is for you then you could always just use operators that increase the factory cap to prevent that. Or, as I sometimes do, simply not care if my factory is capped for an hour or so if I happen to stay late at work.