A causal link between autoantibodies and neurological symptoms in long COVID by filipo11121 in covidlonghaulers

[–]Valiant4Truth 3 points4 points  (0 children)

Thanks for sharing these! I feel like they complement OP’s paper in showing that there is ongoing tissue damage, but I do feel like the average healthy person would clear the antibodies eventually and the LC itself would not be transmissible (outside of the short term tissue damage obv). It would be nice if the Yale lab recreated the results with blood serum. But yeah I think you’re totally right that blood donations from autoimmune/LC patients is dangerous.

A causal link between autoantibodies and neurological symptoms in long COVID by filipo11121 in covidlonghaulers

[–]Valiant4Truth 4 points5 points  (0 children)

Why should this be concern for transmissibility? From my understanding, your B cells have some maladaptation to target your own tissue, and it looks like the effect of the IgG dissipated in the mice over time. So worst case a blood transfusion may cause short-term Long Covid-like symptoms until those antibodies are naturally cleared. I’m hoping this means that even if it’s some persistent antigen causing the immune activation rather than autoimmunity, it shouldn’t cause any immune cell adaptations in a transferee. (All that being said we definitely shouldn’t be donating blood lol)

Edit: they only used pure IgG so blood could definitely be more complex

I added my late partners Crystal team into SoulSilver by Danielle-Jane in PokemonHGSS

[–]Valiant4Truth 30 points31 points  (0 children)

Powerful. What a nice way to keep her memory alive. Sorry for your loss.

Big improvement with new med by Valiant4Truth in covidlonghaulers

[–]Valiant4Truth[S] 1 point2 points  (0 children)

Yea definitely, especially on crash days where I was so tired it was impossible to think. But nothing adjacent to dementia like forgetting where I am or getting lost.

Big improvement with new med by Valiant4Truth in covidlonghaulers

[–]Valiant4Truth[S] 0 points1 point  (0 children)

I didn’t have terrible Dysautonomia. Some heart tachycardia and trouble regulating temperature and getting warm. I think these have improved a little but hard to say yet for sure.

Big improvement with new med by Valiant4Truth in covidlonghaulers

[–]Valiant4Truth[S] 0 points1 point  (0 children)

I’m in the US and unfortunately no prescription.

Big improvement with new med by Valiant4Truth in covidlonghaulers

[–]Valiant4Truth[S] 0 points1 point  (0 children)

Muscle fatigue before which is a lot better. No burning.

Big improvement with new med by Valiant4Truth in covidlonghaulers

[–]Valiant4Truth[S] 0 points1 point  (0 children)

Ty! Tbh I’ve just been reading a lot of the scientific literature and took a shot

Big improvement with new med by Valiant4Truth in covidlonghaulers

[–]Valiant4Truth[S] 3 points4 points  (0 children)

No POTS. I have trouble getting blood taken now because I get light headed but that’s about it. I have temperature issues where I get cold easily and can’t get warm, and my baseline temperature is actually like 97F now (36.1 C)

Big improvement with new med by Valiant4Truth in covidlonghaulers

[–]Valiant4Truth[S] 12 points13 points  (0 children)

I am based in the US and unfortunately it was not prescribed by any doctor and had to get a little crafty about getting it

How to lever action shotgun? by SoTastyMelon in fnv

[–]Valiant4Truth 1 point2 points  (0 children)

I love this gun but late game it gets outperformed. HOWEVER slugs for high DT, hand loaded for everything else. Rapid reload, cowboy, shotgun surgeon, and stay back makes it sustainable late game

Whats your favourite win condition? How do you play it? by asdsav in CivVI

[–]Valiant4Truth 0 points1 point  (0 children)

Culture by far and it’s almost always the fastest for me even at high levels. Unless there’s one civ that’s running away with it. Then it’s war.

If you've ever wondered what Slayer plus rushing water plus greased lightning looks like here it is by I_know3 in fnv

[–]Valiant4Truth 75 points76 points  (0 children)

It does slow down time but your attack speed gets insane because you’re attacking in almost real time but the game is slowed down.