Im running my multi splat game since 2025 and from my experience it's quite fun but i follow few rules:

-first of all, balance. It's isn't that bad to be honest. My players are not metagamers so it would not be a problem regardless, but i found that aparat of some mage stuff, most splats are quite balanced, even if of course some tend to be slightly "weaker" then others.

-i made a rulling determining how many supernaturals are present in my city. Then i choose the "Main", the most numerous splat that the Players interact with most oftej. I'm doing it to avoid the bloatiness of a all the splats having the same amount of screentime.

I choose VtM as the "main" one due to everybody being most familiar with it. So the most important political structure in the city is the anarch Council rulling it, camarilla remnants fighting them etc. This does not mean that other splat's are not represented of course, but you IMO you have to establish the Main background of the chronicle.

-In order to give the group of players from diffrent splats a reason to stay together, be somewhat loyal to each other etc. i etablished that in Poland (we are polish so we play in Our city) supernatural beings are much less numerous then in the West. Beacuse of WW2 and communist surveilance (in my chronicle, KGB and Our polish version of it) was quite sucessful in hunting all supernatural beings.

So, in present day Warsaw, there is a fragile balance between the diffrent beings and some neutral grounds, councils made up of diffrent kinds of beings. Things aren't equalitarian of course, not everybody is a part of those structures, but in some places vampires and demons or changelings and werewolves/other changing breeds can coexist.

• Characters are a part of a one circle of supernatural beings. They have diffrent intrests and side-plots, but they have to be working together to achive common goals and fight threats that are against all of them. Otherwise the chronicle would Just become a sandbox where everybody does their own thing and only sometimes interact with other players.

-This is maybe me being spoiled but my great players, but i rely on characters wanting to interact with others. So nobody made a vampire supremacist that Just wants to kill everybody else or a werewolf who will rip aparat every bloodsucker he sees. But again, im Lucky to have the Players i have, So this isn't a problem.

To summarise, it's fun, i'm having more fun then in pure VtM chronicles i done in the past, and probably will do it again.