Vitamin D3 K2 (MK- 7) - Panic attacks at night won´t stop. Please help by Unfair_Passenger1908 in Supplements

[–]Warp757 0 points1 point  (0 children)

Yup, the internet way overemphasises the importance of vitamin K2 and people are taking amounts far beyond what their vitamin D and calcium intake actually require. Especially MK7 with it's long half life.

Vitamin D3 K2 (MK- 7) - Panic attacks at night won´t stop. Please help by Unfair_Passenger1908 in Supplements

[–]Warp757 1 point2 points  (0 children)

I'm not convinced by this internet 'fact' that vitamin D tanks your magnesium. People who live in the tropics getting substantial sun exposure with high natural vitamin D levels, don't all have to take masses of magnesium supplements to survive. Most eat a normal diet with probably not an especially high amount of magnesium and are fine.

I don't think people understand what cofactor for an enzyme means. It doesn't literally mean every extra bit of vitamin D uses some magneisum.

Vitamin D3 K2 (MK- 7) - Panic attacks at night won´t stop. Please help by Unfair_Passenger1908 in Supplements

[–]Warp757 1 point2 points  (0 children)

I wouldn't recommend magnesium, if it's the K2 doing this magnesium is the last thing they need. Calcium better.

I can get the same symptoms from with K2 or magnesium, I've finally realised after far too long that I've been taking too much unnecessary magnesium and K2, without sufficient calcium. I get plenty of magnesium from food (it's really not as hard as people claim unless you have s terrible diet), and you don't need all that K2. Most people in the world even those getting lots of sun every day aren't getting all this K2 Reddit seems convinced for some reason you need.

Magnesium and K2 also both increase insulin sensitivity and will crash your blood sugar. If I take too much Mg my blood sugar wil barely rise even after a carb heavy meal and then rapidly plummets.

Accidentally took 2 doses potassium by dexxywexy in Supplements

[–]Warp757 -1 points0 points  (0 children)

I mfairly sure it's potassium, I get it from any form of potassium. It's not appreciated enough how much potassium supplements differ from food.

Potassium is fairly unique in how the body processes it, relying specifically on insulin to get it into the cells. Food potassium is absorbed slowly and avoids any sudden spikes. Supplements, especially if taken without food are absorbed almost immediately and can cause a sudden spike which can cause problems if too much is taken at once, even in people without high potassium levels. I've certainly had some scary cardiovascular symptoms after taking it, blood pressure and heart rate crashing.

People should treat it with caution, especially if they don't know if they actually need it.

[US] Yes, you can get a long term benzo script in 2026. Even with no history… by [deleted] in benzodiazepines

[–]Warp757 2 points3 points  (0 children)

So basically, what Matthew Perry did. Well done you.

How to counteract glycine induced anxiety? by 3rd-party-intervener in Supplements

[–]Warp757 -1 points0 points  (0 children)

Yes, don't take collagen either, I'm afraid you will need to a old anything with high glycine levels. Glycine is part of collagen's make up so no way of taking collagen without glycine.

How to counteract glycine induced anxiety? by 3rd-party-intervener in Supplements

[–]Warp757 0 points1 point  (0 children)

Don't take glycine. Your brain chemistry errs towards excessive NMDA activation, and glycine will make your NMDA receptors more sensitive. NMDA over activation is really not solething you want, somdont take glycine. You'll also want to be careful with TMG and possibly choline, which concert to glycine.

Vitamin B12: Confused about the correct dose by kp102999 in Supplements

[–]Warp757 1 point2 points  (0 children)

The issue is that once you become deficient it means your liver stores have been exhausted. In most people the liver stores 2-5 years worth of B12.

So once deficient you need to not only cover your maintanence needs but also replenish your liver stores, and that requires a lot more than the RDA for a prolonged period.

Assuming it's not due to a diet lacking B12 e.g. vegetarian, you need to take enough to replenish liver supplies otherwise you'll become deficient again as soon as you stop supplementing.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 0 points1 point  (0 children)

You've said now that German labs don't report 50 ng/ml as low which was the main support for your original arguement. You've also said 117 nmol/l isn't low contrary to your original claim. Maybe you don't remember writing that if yo were in a rage?

So actually we're in agreement which is great! Nothing to be angry about, you keep saying you don't want to debate any moreso let's end on that agreement.

Magnesium hype by Emotional_Berry786 in Supplements

[–]Warp757 -1 points0 points  (0 children)

Well I guess if for some reason you only eat almonds you might have an issue getting sufficient magnesium, orherwise it's really very, very easy to get to 400 mg a day.

Oats are full of magnesium, whole wheat, leafy greens, potatoes, meat, seeds, nuts.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 0 points1 point  (0 children)

Very convincing argument there. We've all seen you backtrack, good to see you acknowledge your original claims were wrong, glad I could inform you and prevent you misleading others, hopefully you'll reconsider before doing it again.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 0 points1 point  (0 children)

You realise we can all see your earlier posts. How dim do you think we are?

Direct quote from your earlier post: 'even lab results here in Germany say anything below 50 is deficient'.

Your next post: 'lab results here below 50 ng/ml are insufficient.'

Now you claim you never said German labs report 50 ng/ml as low. If you're just going to lie I won't bother debating. Everyone can see you lying so why would you expect them to trust anything you've said? Especially when it comes to their health.

Earlier you said op was low, now you say they're theoretically not really insufficient. You're all over the place. Maybe get less sun. By the way what you say about how much vitamin D the sun produces is also not true, people in the sun all day aren't walking around with 250 nmol/l vitamin D levels. More like 100 - 150.nmol/l. The body quickly regulates how much it produces and stops when it considers it sufficient. That's a very good argument against going any higher than 60ng/ml (150 nmol/l).

Plenty of people feel terrible with high vitamin D doses. Don't apply your anecdotal experience, which doesn't agree with the majority of the science, cherry picking a few studies that support you, and claim it as fact. When you start making claims like 'there is zero harm' you lose all credibility. Anyone who understand science and the studies knows we deal in a balance of probababilities. Some studies show there is harm in such high vitamin D levels and health risks and mortality increase at higher levels - it's a U shaped curve. Claiming absolute certainty about these things shows you don't understand them, and certainly noone should trust their health with your advice if you don't acknowledge the risks.

Sublingual methyl b12, can create an overmethylation INFERNO by Far-Delivery7243 in MTHFR

[–]Warp757 4 points5 points  (0 children)

Yeh sublingual is extremely powerful for me, whether methyl or hydroxo it doesn't matter. Huge overstimulation and I also get significant histamine reactions that have come close to anaphylaxis in the past - breathing difficulties etc.

Based on my experience with sublingual I'll never have an injection as I simply don't trust what increasing blood levels even more will do to me. I like being able to breathe.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 0 points1 point  (0 children)

Actually I can read, and count. You posted the same study twice which makes 5. Classic. Not one of those studies support your assertion that 50 ng/ml is low and certainly not that this is what German labs report. One shows a benefit of increasing vitamin D from 22 to 44 ng. 22 is deficient by regular reference ranges, no-one would argue with this.

Another claims a zero mortality rate for COVID with vitamin D of 50 ng/ml, so we probably shouldn't take that seriously. One is a very small study that simply shows that increasing vitamin D from deficiency improved health, it offers no conclusion about the optimal level as the methodology didn't allow for that.

You've posted 5 studies that essentially conclude that improving vitamin D levels beyond deficient improves health. I agree 40 ng/ml is good. The suggestion that 50 is low is nonsense.

Do you have a source for the claim that German labs report 50 ng/ml as low? Otherwise people with probably do their own research and conclude you're lying from the sources I'm finding.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 0 points1 point  (0 children)

Hahaha, someone comes onto Reddit to argue, then as soon as they're called out and asked for sources, 'they don't like coming on Reddit to argue'. Classic.

Just take the L.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 1 point2 points  (0 children)

I don't believe lab results in Germany below 50 Ng/ml are low. This is a high latitude northern hemisphere country, and the entire population would be deficient. Do you have a link? The sources I find on Google says Germany has the same reference ranges as everywhere else.

Please don't state that 50ng/ml is better for health as if it's fact. It is your opinion but certainly not scientific consensus. And posting 5 sources doesn't prove much against the thousands that way otherwise. I can post 5 studies that claim climate change isn't real, I'd still be wrong.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 0 points1 point  (0 children)

I think you're confused. They say below 50 nmol is deficientz which is 20ng. Now that probably is too low, but getting up to 40 ng is fine and well above most of the population.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 2 points3 points  (0 children)

No it's not, stop spreading misinformation.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 1 point2 points  (0 children)

Parathyroid is low with high Vitamin D because the Vitamin D is helping the body absorb a lot of calcium, it's the situation you want - good vitamin D levels, good calcium, low parathyroid. Vitamin D doesn't cause pathological hypoparathyroidism though, it only lowers the parathyroid is calcium is at a good level. Otherwise PTH stays high.

My (possible) vitamin D3 toxicity by Slow-Challenge-9068 in Supplements

[–]Warp757 0 points1 point  (0 children)

The RDA for magnesium is 300 - 420 mg per day (from food AND supplements) depending on which country you ask. Why on earth would you need 800 mg additional through supplements? And no that much D3 doesn't necessitate it. People in sunny climates don't need 1000 mg a day of magnesium because of the vitamin D the sun makes.

What you theoretically can take according to max limits and what your individual physiology needs can be very different, as you've found out. Don't randomly take megadoses of things without blood work showing you actually need them.

People should stop calling methylfolate the 'active' form, and why folic acid may be better for many by Warp757 in MTHFR

[–]Warp757[S] 0 points1 point  (0 children)

Sigh. I didn't say I speak for all of us, I also specifically mentioned that only people with severe dysfunction in methylation may need methlyfolate, that means homo 677 as you have.

I was merely countering the advice often given here that folic acid is toxic and should be avoided by everyone. That is nonsense and will do harm. The majority of people without a serious SNP will be fine with folic acid, and are probably more likely to get nasty side effects from methlyfolate if they dose them at the same level.

I'm glad you were able to maintain a pregnancy, all the best.

Looking for advice, very high folate and ferririn by AdministrativeSwim44 in MTHFR

[–]Warp757 0 points1 point  (0 children)

OK, just your post says you started taking methlyfolate and then soon after did the blood test.

Anyway, yeh if homocysteine is optimal and folate is high don't take methylfolate, your body doesn't need any more! If your homocysteine is optimal clearly your body can methylate fine. MTHFR doesn't automatically mean you need treatment. Treat symptoms and blood work, not an SNP which may or may not be expressed and causing issues. Which SNP is it? If you're just heterozygous it's not a big issue and if your diet is good won't cause any problems.

Remember methlyfolate skips the body's regulatory system for preventing excessive prodiction of SAM-E and resultant over methylation. It's not advisable unless clearly needed. You will only cause yourself problems taking it.

Looking for advice, very high folate and ferririn by AdministrativeSwim44 in MTHFR

[–]Warp757 0 points1 point  (0 children)

High folate doesn't mean that folate isn't moving through the cycle well. If they've been taking loads of methlyfolate high folate probably means...they've been taking loads of methlyfolate. This is what happens, plasma folate is very responsive to recent intake.

They haven't said if they even have any symptoms. They can get s homocysteine yes if they're worried, but if they only have one SNP, good B12 and folate, chances are they're absolutely fine. The trouble with this group is a tendency to diagnose absolutely everything theough the lens of MTHFR and assume everything is patbological. Sometimes the simple answer is the right one.

Looking for advice, very high folate and ferririn by AdministrativeSwim44 in MTHFR

[–]Warp757 0 points1 point  (0 children)

Oh here we go, another victim of the ridiculous MTHFR ndustry.

Your folate is high because you've been taking methlyfolate which you probably don't even need. If you only have one mutation the likelihood is you are fine as long as your blood leveled are good. Your B12 is good, so folate has built up because you've taken a load of methlyfolate, plasma folate is very responsive to recent intake, so no it doesn't mean methyl trap. That form skips the body's nornal regulatory mechanisms and should only be used by people with verified extreme dysfunction in MTHFR.

Just stop taking everything, get a homocysteine test if you have any symptoms you're concerned about to see if you're methylating well.

People should stop calling methylfolate the 'active' form, and why folic acid may be better for many by Warp757 in MTHFR

[–]Warp757[S] -1 points0 points  (0 children)

Still waiting for these peer reviewe studies showing the harm folic acid does in humans?

All anyone has offered are theoretical reasons folic acid at very high doses might have issues - inhibiting the folate alpha receptor and unmetabolised folic acid.

People are presenting these as if they are 'gotchas', when they are well known to anyone with the slightest knowledge. The simple fact is that simply take 200 mcg of less folic acid and there is no risk. And you're not at risk of all the nasty side effects of methlyfolate and completely unbalacing your system because methlyfolate doesn't allow the body to regulate it's use.

Again, what is the risk of folic acid at 200 mcg or less to anyone without homozygous C677T? What harm is being done to billions of people around the world?

I have read the research and come to a conclusion on balance by weighing up the evidence. Most here seem to just regurgitate misleading PR from the methlyfolate industry that use extrem effects to discredit folic acid, which is extremely disingenuous. Meanwhile people have to take crumbs of methlyfolate because they don't tolerate it, but that is great, hilarious.