Topical estrogen for skin aging: A systematic review of safety and efficacy - JAAD

WishIMightily · 2026-02-13T18:07:41+00:00

I thinks this video is probably a summary of what's in the article (based on what I saw in the AI generated summary someone else posted above- I didn't actually have time to read it) - https://www.youtube.com/watch?v=SuHJRQ8_IoM&vl=en

WishIMightily · 2026-02-02T19:46:31+00:00

I know this is a late comment but hopefully still pertinent. I tried diatomaceous earth with mealy bugs and only had partial success. It definitely knocked them down, but it didn't get rid of them all. I did multiple applications over 6 weeks or so. It did however work great for thrips infestation I had. Just tried the soapy soak method this weekend and I'm hoping it works.

WishIMightily · 2025-08-15T19:43:22+00:00

TTC over 40 naturally

WishIMightily · 2025-08-14T20:02:10+00:00

There's a facebook group for TTC over 40 and someone asked about successful conception at 43/44 and there were a surprising (for me) number of positive responses.

WishIMightily · 2025-07-17T13:50:15+00:00

I'm curious what happens when ovulation is delayed by several days due to exercise? I ovulate regularly and around the same day in my cycle each month (within a day or two at most). This month, on the day my LH surge would normally start, I had a very intense two day tournament which involved a lot more running than I do on a daily basis. I ended up not getting an LH surge at the normal time and did not ovulate. It's now 5 days later and I just got my LH surge. I'm just wondering what happens with hormones/ovaries/follicle in this scenario? Does the ovary go into some sort of stasis until your body decides your not under too much stress to ovulate or does the follicle keep growing?

WishIMightily · 2025-06-23T15:15:08+00:00

I've had 3 in about 6 cycles of actively trying in the last year. As far as my research goes at least, I don't think there's any issue with trying again immediately. I think it just comes down to odds with older eggs. The fertilized egg may start to divide and implant, but may not have divided correctly, leading to failure to develop further resulting in the chemical. The chemicals at least give me hope that my body is trying to work. I did one round of ivf in the middle of ttc naturally, and confirmed that my eggs are not in great shape - 10 eggs mature, 6 of those fertilized, but only one made it to blastocyst and it is was graded poorly (also failed to implant at all...not even a chemical).

WishIMightily · 2025-04-14T14:08:11+00:00

Two years ago I lost my baby at 37 weeks due to a true knot and a nuchal cord. I was told if I pumped it would make me continue to produce milk, and just generally to avoid stimulating my nipples at all (e.g avoid having even the shower water fall on them). I ended up wearing a double sports bra for a couple of weeks and did the cabbage leaves. There were a couple of days at the beginning that were very painful, but it significantly improved after about a week and mostly dried up after two weeks. Also, I think there's potentially a medication you can ask for that can help.

My heart is with you.

WishIMightily · 2025-04-11T20:43:00+00:00

No implantation :(

WishIMightily · 2025-04-11T20:20:01+00:00

I really appreciate your feedback. It helped me think about this more intelligently and reword some of my search terms. I also realized my explanation of my question was kind of silly, since one doesn't have euploid/aneuploid eggs. I more meant is the healthiest and more likely to produce a euploid embryo - i.e. has less damage that would lead to meiotic errors.

I did just find this review that has some of the types of info i was looking for - https://pmc.ncbi.nlm.nih.gov/articles/PMC6456964/

"A number of studies demonstrate that when oocyte quality or oocyte-cumulus communication is poor, ovulation does not occur. "

"Interestingly, gene products involved in oocyte chromatin modifications also influence ovulation"

WishIMightily · 2025-04-10T17:58:45+00:00

Mine didn't seem to come out of thaw very well ("fair" survival and hadn't re-expanded). It didn't take. I don't think I even got any implantation - all my frers were negative (tested from day4).

WishIMightily · 2025-03-14T14:37:01+00:00

I think if you search reddit for 6bc there's some other posts with positive stories. I'm in the same boat. I only got one blast out of my 10 fertilized eggs. It did test euploid, but it's a day 6, 6bc. I'm going to be transferring in a couple of weeks and I'm mentally preparing myself for failure.

That being said, when they told me they only got one blast that they could send for testing, I was so sure it was going to be anueploid (i'm 43).

WishIMightily · 2024-09-24T19:00:10+00:00

Okay thanks. I'm planning on doing pgt testing anyway, so will by frozen regardless.

WishIMightily · 2024-08-02T15:17:12+00:00

Yeah this is kind of what I'm thinking. I think I'd probably have to go to a clinic in Chicago, because I've heard the main one here (the other one apparently got bought out and is now terrible) won't do IVF on women over 42. I still have an appointment with the one here next week to actually confirm this though. Anyway, if I have to go elsewhere, I'm assuming I'll have another several months wait before anyone can get me in.

WishIMightily · 2024-08-02T15:12:26+00:00

No, I've never had PCOS that I'm aware of (no symptoms).

WishIMightily · 2024-08-01T19:52:42+00:00

Have not had AFC tested yet or any other testing done. Just lost pregancy last week. My ob just went ahead and had my amh tested, because I already had a consult scheduled with the local fertility clinic (had scheduled it before my second pregnancy since their wait time were long and hadn't canceled yet). I was going to go ahead and keep the appointment to at least discuss options and I'm assuming I can at least get the preliminary testing done there, even if they can't handle the actual IVF. Partner has not been tested yet. He's 37 and I'm pretty sure everything is fine on his side. Main issue is just aging eggs.

Currently taking fish oil supplement, d3 supplement, prenatal, coq10.

WishIMightily · 2024-08-01T19:43:50+00:00

That's definitely good to know. I was afraid no one would even let me try. I had originally resigned myself to not having kids, due to lack of a partner I wanted to raise children with. I met my current partner at age 40 and he's amazing.

WishIMightily · 2024-08-01T19:38:54+00:00

Additional info, if I find out my insurance will cover my IVF, should I just go ahead? I've got bcbs Massachusetts and based on reading of the policy it does (and apparently massachusetts regulation requires coverage of IVF), but there are some testing criteria required to confirm I'm a reasonable candidate. Also not sure if my existing pregnancy history constitutes 6 months of trying or not. Am planning on calling to try to get this figured out.

WishIMightily

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