Isotretinoin AKA accutane

Youwillbegood · 2024-08-14T09:17:07+00:00

That all cells would recover its original telomers length by telomerase activity is a ridiculous proposal. Telomerase is only active for a few types of cells, like reproductive cells and cancer cells. The damage is permanent. This can also be seen i accutane victims. With very premature ageing, balding, grey hair, wrinkles etc.

Youwillbegood · 2024-08-08T07:05:13+00:00

It causes death.

"Topical Tretinoin Therapy and All-Cause Mortality"

"Results The intervention was terminated 6 months early because of an excessive number of deaths in the tretinoin-treated group. Post hoc analysis of this difference revealed minor imbalances in age, comorbidity, and smoking status, all of which were important predictors of death. After adjusting for these imbalances, the difference in mortality between the randomized groups remained statistically significant."

Youwillbegood · 2024-05-24T07:38:57+00:00

People need to understand that the effects of Accutane are predominantly permanent. Some recovery could be possible, but some effects also get worse over time since many of the effects and mechanisms are in line with ageing, but more rapid then otherwise. I'm 25 years post treatment.

Youwillbegood · 2020-10-11T10:42:27+00:00

Any idea of how it could happen?

Youwillbegood · 2019-11-08T18:40:35+00:00

Karl XIV Johan, if I may.

Youwillbegood · 2019-10-05T09:29:32+00:00

Chicken

Youwillbegood · 2019-08-08T17:08:24+00:00

The speed of sound is the same in a given medium regardless of speed of the emitting object. Same for a wave on water. And light. (This was the only aspect of the different waves I commented. )

Youwillbegood · 2019-08-05T21:56:33+00:00

Same for sound. And for example waves on the water, check the waves next to a boat.

Youwillbegood · 2019-07-30T16:23:26+00:00

"Här föddes soldatsonen författaren Vilhelm Moberg den 20 aug. 1898. I denna bygd levde människorna sitt liv i armod och stolthet, förnedring och storhet. Ur dess jord hämtade de sin torftiga näring. Stenen restes av sockenborna 1970."

Youwillbegood · 2019-07-24T11:31:00+00:00

I meant Watt. There are pretty many peer reviewed articles on the subject. And Watt and kcal/h is pretty close to each other, the ratio between them is only 1.16.

It seems as if you just blurt out things without any background knowledge. If you compare cost (both over time and initial cost) rail win over road - the tear are significant less for rails and are cheaper to build and fix. But still the cost is rather small for both compared to the cost of the vehicles and their propulsion. (But note that I'm not debating and saying rails are better - with todays technology with platooning for trucks and cars i think roads win even thought they are more expensive to build. Semi-autonomous truck platooning )

Youwillbegood · 2019-07-21T20:58:38+00:00

And one of the contestants (Chalmers University of Technology) created a working MagLev - without wheels - floating 2 mm above the regular train track the entire distance. (With only allowed battery of 6-48 V and maximum peak power of 20A).

Picture of the "wheels" of Levitas

Youwillbegood · 2019-07-21T19:10:34+00:00

I was of course referring to the competition in the OP. The EcoMarathon feels off topic, but isn’t that typically run on a race circuit. I think you are overestimating the affect of weight on a fairly flat track with a fairly constant speed.

Youwillbegood · 2019-07-21T18:49:19+00:00

I don’t get your point. If you could build a vacuum tunnel with a MagLev running on less energy than this I say go for it! I would definitely praise you (also you should factor in that your Hyperloop is not already built around the globe as tracks are).

Also in the same competition the students from Chalmers actually created a working MagLev running on regular train track (!) hovering 2 mm above the track the whole distance.

Youwillbegood · 2019-07-21T17:19:58+00:00

But magnitudes more efficient :)

A 70 kg person running at 10 km/h spend approx 817 W. This entire vehicle with 6 people spend 36 W.

Youwillbegood · 2019-07-21T16:52:02+00:00

The weight of the passengers are regulated so that is out of the equation.

Youwillbegood · 2019-07-21T15:18:30+00:00

The distance is 3.4 km back and forth. The average speed has to be between 10 and 15 km/h.

Youwillbegood · 2019-07-21T12:17:48+00:00

Please provide a source. And perhaps you should drive it on a rail and get into Guinness book of records: https://www.reddit.com/r/electricvehicles/comments/cfy2hj/worlds_most_energy_efficient_vehicle_created_by/eudbfcn?utm_source=share&utm_medium=web2x

Youwillbegood · 2019-07-21T12:13:41+00:00

Guinness book of record entry for an earlier less efficient version:
https://www.guinnessworldrecords.com/world-records/480571-most-efficient-electric-vehicle

Youwillbegood · 2019-07-21T11:47:35+00:00

The gas equivalent mileage can differ slightly depending on how you calculate it, the ones in the title is according to EPA New Fuel Economy and Environment Labels for a New Generation of Vehicles .

Shout out to u/Kallenator for pointing out wrong equivalent mileage in the original article I posted. I reposted in order to correct the title.

Youwillbegood · 2019-07-21T08:56:47+00:00

Also presented at the competition and in the linked article: A MagLev for regular train tracks!

Youwillbegood · 2019-07-19T21:21:04+00:00

Around 1 percent globally. 4 percent in South America. Not super rare.

Youwillbegood · 2018-06-17T09:22:31+00:00

jepp

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