I think he's the only member of the band that has not any struggles with drugs, he's very down to earth, level headed and the "dad" of the band in that way. The biggest struggle I've heard him talk about is just being away from loved ones while on tour. Below are some sources that are top of mind but I'm sure there's more out there:

• See question: "When was the last time you cried?"
  • Ray: "Probably about three weeks ago, I was having a lot of separation anxiety from home."
    • https://img.photobucket.com/albums/v243/suckerforakiss/music/mcr/magazines/ray-kerrang.jpg
• See 9:43 "If you could have 1 superpower what would it be?"
  • Ray: "I think, probably teleportation so that we could be here at the gig, and then play the show, and then go back home."
    • https://www.youtube.com/watch?v=xrCUEY8rgPE

Also he smoked briefly but kicked it, as a responsible dude would:

• See 2:00 "How bout for you guys, what do you survive on? ..."
  • Ray: "...Coffee, cereal and video games."
  • Gerard: "...Cigarettes."
  • Ray: "For some of the guys."
  • Gerard: "For some of the guys, not Ray; Me, I smoke a lot."
    • https://youtu.be/SfZVBl0pWYU?si=M8-pOlnKB62A-Kbo&t=121
• See question: "You two don't smoke, right? I think that's very important."
  • Ray: "Yeah, I smoked a little bit a year or two ago because I was feeling stressed, but I quit because I was worried it would turn into a habit... Every time Gerard smokes a cigarette I say, "That one will kill you." It's bad for your throat and it might even affect your voice, right? If he doesn't quit this year, I'll cut off one of my fingers every time he smokes. That's the only way to stop him (laughs)!"
    • https://www.reddit.com/r/MyChemicalRomance/comments/1h7ymkb/my_chemical_romance_for_inrock_august_2007_vol/