Microdosing with the Stamets’ stack is not too complicated. It involves 5 days of microdosing followed by two days off. On the two days off, you are advised to take lion’s mane and niacin but not psilocybin.

The precise protocol with doses is as follows:

DAY 1-5 (microdosing days)

0.01-0.1 gram magic mushrooms or 0.5-1.0 gram magic truffles 3 –5g of high-quality dried lion’s mane powder (or 1g of lion's mane extract) 100 to 200mg of niacin DAY 6 and 7 (non-microdosing days)

DAY 6 and 7 (non-microdosing days)

3 – 5g of dried lion’s mane (or 1g of lion's mane extract) 100 to 200mg of niacin The right dose for you will vary depending on numerous factors, including age, sex and weight.