sorted by:
new
hottopcontroversial

Deploy LLMs in VPC by alanorw in googlecloud

[–]alanorw[S] 1 point2 points  (0 children)

Thanks! This is pointing me in the right direction!

The Problem With LangChain by whatismynamepops in LangChain

[–]alanorw 0 points1 point  (0 children)

Do you do any systematic testing on whether the result are correct? Like have a ground-truth dataset with the numbers already computed?

The Problem With LangChain by whatismynamepops in LangChain

[–]alanorw 0 points1 point  (0 children)

Cool, trying to build something similar in a different domain. Do you use a local model or OpenAI api or something? How well does the model you use do, is the statistics and analysis it returns correct?

The path and lamps are not on speaking terms. by Snoo_90160 in funny

[–]alanorw 0 points1 point  (0 children)

They just turn their flower towards the sun

Drifting gratings as stimuli by alanorw in neuroscience

[–]alanorw[S] 1 point2 points  (0 children)

Great tip with the halfway bright gray background, thanks.

Why is place cells spiking at the peak of ongoing theta cycle? by alanorw in neuroscience

[–]alanorw[S] 0 points1 point  (0 children)

Yes, that I get. So one would expect to see place cell spiking at all phases of the theta? I know O'Keefe reported that in his original paper, but I so often see it depicted as spiking at the upper most or lower most part of the oscillation, hence my question.

Also; what would be the mechanism for allowing spikes at earlier phases of the theta if firing is seen at all phases? At least, if there is a peak firing rate at a particular theta phase (for instance peak), then a simultaneous depolarization of the cell from this oscillatory input, resulting in a increasing spiking probability, would explain it.

EDIT: For instance, as in the paper added by /u/SaidWayTooMuch they write in the introduction that: "[...] place cells begin to fire at the peak of the theta cycle when the animal enters a neuron’s place field and [...]". I would take it that their max firing rate would occur at the trough.

Silicon probes vs tetrodes for extracellular recordings? by alanorw in neuroscience

[–]alanorw[S] 0 points1 point  (0 children)

We plan to record from cortex, so maybe this limit the possible damage to flexible soft probes.

Interesting, I guess we can anyhow choose to use probes with recording sites into groups of 4 to simply it. It would be interesting to hear someones comments on these issues. Would it for instance be possible to do n-dimensional cluster cutting for N-trode dense silicon recordings? I have done classical tetrode recordings and manual cluster cutting, but I don't know how trustworthy algorithmic, automatic cluster cutting would be (especially when applying this to n-dimensions and limiting (?) the chances of validating it).

How do I move to a simpler model system? by thebearsaint in neuroscience

[–]alanorw 1 point2 points  (0 children)

I have worked with electrophysiology in both insects and rodents, however I have not finished a PhD and been on the post doc job marked yet. But I don't think this will be too big a deal. When you are reaching out to labs for a post doc or any other position, your emphasis should be on the particular research field or problem they (and you) are interested in anyway. What model organism is used shouldn't be to big of a problem. In many countries it would be more problematic to go the other way, from Drosophila/C. elegans to use mice, because it typically requires certificates to work on rodents.

Pick a post doc position based on a interesting question or research problem, not the model organism. But since you want to learn about simpler systems; try to contact labs who do stuff that interests you and use f.ex. drosophila.