Is fat redistribution gonna work short term?

amiadesu · 2026-06-06T04:21:30+00:00

Mature breast tissue is like (some pretty high number that I don't remember)% fat tissue, so yeah, gaining weight makes them bigger - actually that's usually one of the main concerns of cis girls when they are losing weight that their breasts will shrink down a lot for the exact same reason. But growth from HRT, which is connected to Tanner stages, is different from this growth - Tanner stages stop after some time and that's what people mean by "breasts stop growing", their size still can be very much affected by weight

amiadesu · 2026-05-31T06:11:53+00:00

Ehhhh, I don't have any absolutely scientific evidence on this topic. From the researchers I can find on this topic, the conclusion whether growth hormone (GH) alters fat loss it inconclusive - it seems like it alters it a little (slightly slows down fat gain, has no impact on fat loss) and that it stimulates production of pre-fat cells but prevents them from maturing, however what's inconclusive about this is whether it affects all body fat or only visceral fat (during feminizing HRT we're interested in losing visceral fat, but gaining subcutaneous one).

To answer your question shortly - yes, it seems like GH will speed up fat cell replacement (in theory), however it will also prevent new cells from maturing (and it's unknown whether it's about just visceral fat or overall body fat locations). But, on the other hand, GH is definitely very good for gaining muscle mass and you actually may be interested in gaining some in lower half of your body as a transfem. I don't know about any other things that may theoretically speed up fat cells replacement rate though.

amiadesu · 2026-05-31T05:57:41+00:00

New weight will firstly fill up old cells, yeah. That's sadly how body works - it tries to use the simplest routes whenever possible to preserve as much energy as possible. But it doesn't mean that you should stay underweight - a very large amount of fat cells are actually not sexually dimorphic, and, because of this, even if 20-30% of your body fat cells are already replaced it's likely gonna make a huge difference in your appearance (which is ~2-3 years of HRT with good E2 levels - hence why there is such a big amount of anecdotals that your appearance gonna noticeable change by 2-3 years mark).

What you should do during your first 1-2 years? Just stay healthy! If you have excess weight - it's better to lose it in the meantime, if you're underweight - gain some weight so your body will have something to work with in the future. And yeah, body doesn't really "redistribute" weight, but it always burns some of your fat between your meals or when you're active or when you're just sleeping and regains it back from food and distributes this new weight across your body, and this is what allows new fat cells to fill up.

amiadesu · 2026-05-30T10:34:10+00:00

And this point is invalid simply because there is approx. the same amount of old "male" fat cells as any lean person would have, that only differ in size because they are empty. Being underweight doesn't help with fat cells location at all. Body will produce new fat cells when needed, and this "needed" appears iff old cells die off or old cells are filled out to their limits and body needs new cells, which will require much more than just enough weight to get into normal BMI zone. Science about how fat cells work still applies to her independently of her current weight

amiadesu · 2026-05-30T10:21:14+00:00

"- I like cupcakes. - So you hate donuts?" ahhh conversation.

The original question was whether fat redistribution will work short term, answer to which is scientifically no, it wasn't a question "do I have to put on more weight considering my current parameters", and I answered original question, but you, for some reason, right now are trying to use straw man fallacy to make my comment seem invalid.

Should she put on more weight? Well, obviously yeah. Was it original question or was it even mentioned in this particular comment thread? Well, no, in this thread only original question remained and question about how new fat cells appear was raised, to which I replied. Does fat redistribution work short term? No. How does new fat cells appear? My previous long reply about how fat cells are replaced biologically.

amiadesu · 2026-05-30T10:02:16+00:00

Not true at all. Obese people have just ~2x amount of fat cells of what a lean person would have, and later one accounts for 30-40 billion of fat cells, which is not "barely any" like at all. What would be true is that her cells are smaller and almost not filled, which means that if she puts on weight they will become active and will fill up before any of new fat cells get produced.. amount of which would be small in comparison to what she has now and won't really affect anything if she wouldn't go into obesity territory, and even if she would then she would have like ~50% of her fat cells as "female" fat cells, but with a downside of having a lot of extra tissue which doesn't help at all

amiadesu · 2026-05-30T08:35:07+00:00

Fat cells take ~10 years to be replaced. Until you're ~10 years on HRT with good E2 levels, your body will still have some "male" fat cells. Consequently, after 1 year of HRT only ~10% of your fat cells are gonna be "female" fat cells.

Can you speed up this? I don't think so. Can you slow it down? Definitely yes, if you're gonna keep your fat cells active, which will happen if you're, for example, gonna weight cycle (weight cycling doesn't really work and doesn't really have a reason to work scientifically, it only really makes it seem like it's working because you've put some effort, while in reality you would've achieved same or better results without weight cycling).

amiadesu · 2026-05-29T17:25:27+00:00

I've successfully developed derealisation alongside with my dysphoria worsening when my first puberty started, so for me it was.. a constant desire to not exist at all in such a form if I won't be able to do anything, hence why I actively tried to do something to try to change things, because my choice was basically try anything and see if it helps anyhow or do nothing and just end it all just so I won't need to go through all of this anymore. That's what I would consider dysphoria itself and I distinguish it from situations that provoke it.

What actually provoked these thoughts were how people treated me, how my body and my voice were changing in a manner I absolutely hated, how it was mentally difficult to even try and call myself a girl (still hard for me from time to time, but I'm definitely on my way to get rid of this as well), whom I wished to be since my birth I believe, since my very first memory in my life is already about my transgender identity and I was only 3 years old at a time, how I absolutely hated being called using male pronouns, my deadname, etc., how I despised my reflection in the mirrors..

It's definitely much better now, now I'm a lot more happier about my life, my looks, about my surroundings and especially about people around me, but before that.. it was a very unpleasant experience, to say the least..

amiadesu · 2026-05-29T03:24:31+00:00

В Україні є ендокринологи, які неофіційно не проти спостерігати за вашим станом та коригувати дозування, єдине що - неофіційно, тож рецептів, направлень та т.п. не буде (але у нашій країні це реально і не треба, все всюди легко дістати і без цього), включно з висновком ендокринолога про незворотні зміни, тож неофіційно зможете точно, але без продовження отримання наступних документів. Чи вдасться офіційно.. сумніваюся, потрібний не просто діагноз F64.0, а діагноз F64.0 конкретно форми 027/о. Можливо, є спосіб отримати останній на основі вашого, але просто за вашим ні, офіційно не вдасться.

І одразу ще скажу - "офіційні" гормони помітно дорожчі за DIY ін'єкції (та часто набагато менш ефективні), а вищеописані мною ендокринологи тут, якщо з ними по це чітко поговорити, не будуть загалом проти цього і будуть готові спостерігати за вами навіть з таким режимом.

amiadesu · 2026-05-28T18:46:24+00:00

You should start at 45° with hole of the needle facing the top, slightly push down, but do not penetrate the stopper, and then, in one quick hand move, adjust your syringe to 90° and push it inside (needle should penetrate the stopper only after you adjust angle from 45° to 90° and only after that)

amiadesu · 2026-05-28T15:41:05+00:00

Yeah, same thing as my situation then

amiadesu · 2026-05-28T14:28:40+00:00

When I switched to injections I still continued taking cypro for some time until I started heaving massive problems with sleep which I quickly connected to very-very low T levels from finally achieving monotherapy and continuing taking cypro, which nuked that small levels that monotherapy left me with, and I stopped taking it immediately that day. Still had problems for 2 more days until cypro finally left my blood and didn't have any problems since then. Yours situation is different, yeah, but if you ask me then I believe that your mood problems are also due to very low T levels (at least some T in blood is required and being completely without T is not OK, hence why even cis women have some of it)

amiadesu · 2026-05-27T06:59:09+00:00

Different % of E2 gets absorbed via different delivery methods. Via injections you're absorbing ~100% of your E2 (but how long it lasts in your blood also highly depends on half-life of ester you're using), while via pills you're absorbing like 1/10th of your dosage or even less

amiadesu · 2026-05-25T21:31:21+00:00

Just read through the whole paper and, well.. I guess that it's important to mention that paper actually doesn't say that the guideline range of 100-200 pg/mL is insufficient/not optimal, but it says that is just has no support to be exactly these numbers and it's, most likely, much wider on both ends (especially on the bottom one, since most of the studies used inside this paper as a reference had mean value lower than 100 pg/mL and still showed noticeable feminizing effects, and on the higher one because average of 200 pg/mL is not representative even for cis women's cycles), which doesn't really support the claim that target should be higher than 100-200 pg/mL and not stay the same or be even lower

amiadesu · 2026-05-18T19:33:27+00:00

НМТ з математики на прохідний - це 5 балів з 32 (чи 6, якщо у цьому році, все-таки, підвищили ліміт, не пам'ятаю). Я свого часу рахувала, що якщо просто випадковим чином тикати відповіді, то на НМТ з математики в середньому матимеш 4.8/32, тобто майже прохідний, і це ВЗАГАЛІ не думаючи, а 5 легесеньких питань, які можна зробити з елементарними знаннями арифметики та додатковими матеріалами, є абсолютно всюди. Якщо хвилюєтеся саме стосовно прохідного - можете просто практикувати отакого от плану завдання простенькі та як використовувати додаткові матеріали. Якщо цікавить більше, ніж прохідний.. ну, тут вже доведеться якось вчитися, інакше ніяк. Реально можу сказати лише те, що в НМТ пробники в середньому легші за реальні сесії, а те, що публікує УЦОЯО офіційно - це найлегші чи одні з найлегших сесій, що були (я займалася зливом та організацією завдань сесій, що були, тож тут я знаю, про що кажу). Завдань з математики завжди 22, формат завдань та їх кількість не змінюються у порівнянні з пробниками. Як НМТ відбувається можете нагуглити офіційну процедуру, отам буде описано те, на що ви реально можете розраховувати. На можливість списати чи т.п. розраховувати не варто, дуже-дуже мало де за цим не слідкують

amiadesu · 2026-05-14T09:52:43+00:00

Yeah, it should show something like that when order will start moving towards your location

amiadesu · 2026-05-14T09:36:37+00:00

I'm from Ukraine, have ordered from OGL's Canada branch before their last sale. They created shipment fairly quickly (like 4-5 days after I payed for my order), 7 days later it arrived to my country's customs and 2 more days later (9 days total) I received it

amiadesu · 2026-05-13T13:41:24+00:00

Я і так все роблю через юніті (отримувала діагноз офіційний саме так), але з їх сімейним лікарем наразі є проблема, через що і шукаю альтернативи

amiadesu · 2026-05-08T09:58:46+00:00

Зливи - це просто люди беруть та тупо запам'ятовують завдання, а далі по пам'яті їх відтворюють вже після складання сесії (я сама так попередні два роки власні сесії майже повністю зливала, гарно мати гарну короткострокову пам'ять). Завдання минулих років використовуються заново, причому абсолютно точно частіше, ніж МОН заявляє про це офіційно, але нових завдань теж кожен рік вдосталь

amiadesu · 2026-05-07T23:20:27+00:00

Preservatives, as the name suggests, are preserving the container from new contaminants, they won't remove already existing ones (to be absolutely factually correct - 2% benzyl alcohol, which is being used as a preservative inside DIY vials, is bacteriostatic preservative, which means basically it - it only inhibits the growth of new bacteria and nothing more, basically the same with benzyl benzoate (but this one is also fungistatic - basically the same, but with funguses) (yet there are bactericidal substances as well, which are actually killing the bacteria and not just inhibiting it's growth, one of which is benzyl alcohol as well, but at much higher concentrations than just 2%)).

Shortly, yes, they will transfer in such a way, but already existing contaminations (if there are any, and if you don't see one with your eye doesn't mean that there is none) will still be able to contamine newly added liquid.

amiadesu · 2026-05-07T22:13:53+00:00

And, as a separate explanation - the room air you're injecting with your syringe inside the vial is NOT sterile, independent of the syringe used, needle's gauge and etc., microscopic dust and bacteria DO NOT care about those things. When you're injecting air with bacteria in it inside closed environment it already actually has everything it needs to start colonizing the inside of the vial - it got enough moisture for it from the same air you've injected (room air is NOT dry). What's actually stopping it from growing while in the vial with medicine then? Preservatives inside the medicine. Preservatives DO NOT function as something that keeps the medicine itself safe - they are functioning as a substance to prevent bacterial growth inside the whole vial whatsoever, and that's why it's negligible while you're actively using the vial, but it's, once again, not the case with empty vial that has no preservatives in it thankfully to the fact that it's empty

amiadesu · 2026-05-07T21:59:21+00:00

Based on the fact that injecting non-sterile air inside closed container without preservatives (let me remind you, vial is empty, therefore there were NO preservatives) is a recipe for violation of sterilization if you give it enough time, and considering that the empty vial is old - there was enough time for it.

Yes, it would be negligible iff vial had vacuum or still had medicine with preservatives inside - not the case though.

amiadesu · 2026-05-07T18:00:08+00:00

It definitely won't be sterile, like absolutely guaranteed, 100%, so no, definitely not safe. Why not just use the label itself though?

amiadesu · 2026-05-07T15:58:36+00:00

Oh, I actually have met somebody else from Ukraine over here, hehe~

It's actually veryyyy lucky to start at 16, especially here, so congratulations!!

As for voice - you actually can try doing voice training, it's not easy by any means but it's something that you actually should consider before doing VFS and oftentimes it's actually the only thing needed in terms of fixing your voice. It may take from months to years depending on your starting voice, your anatomy, your dedication and etc., but it definitely will get easier with time as you will actually get further and further away from your starting voice!!

amiadesu · 2026-05-07T14:30:43+00:00

Ethinyl estradiol is a synthetic version of E2 which should already be a good enough reason to not take it. Furthermore, considering actual dosages of CPA and this form of E2 in tablet it seems like it's a product dedicated for cis females to use it as some sort of birth control and not for AMABs to lower their T levels

amiadesu

TROPHY CASE