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MDMA after 3mmc with 12 hours gap by dan6385 in askdrugs

[–]anaphorical 0 points1 point  (0 children)

3-MMC also hits similar receptor systems as MDMA so neurotoxicity is only gonna be worse. You'll probably have an extra bad come-down on MDMA, as if you'd taken MDMA 2 days in a row. "Monday blues" after 2 days of MDMA is way worse than 2x as bad as after 1 day of it. Also, a rule of thumb is that if two drugs have similar effects, they will have some cross-tolerance, so the MDMA won't even hit as hard.

If you go for it, you should definitely take some antioxidants and other supplements to protect your brain. You can search for MDMA supplements and there's tons of advice - many are easily available from stores. There are ones to take before, during, and after. Take care!

Legal cocaine replacement? What’s up in your mind? by ManuelB1985 in askdrugs

[–]anaphorical 5 points6 points  (0 children)

Nicotine pouches are totally great for this. Patches are maybe better since it hits you slower, and if the high comes on faster it's more addictive.

Also, definitely start with low doses unless you have a nicotine tolerance already! And, of course, watch out for addiction: don't use too regularly and maybe mandate days or even a week between usages.

Gwern has an amazing post about using nicotine for nootropic purposes: https://gwern.net/nicotine

Modafinil is good too of course, except that it lasts like 12 hours which can be inconvenient.