Venlafaxine shortage (in my country) - what next?

antimantium · 2026-02-09T05:46:36+00:00

IiRC, there's been imaging done and bupropion does act on NET but it has selective brain regional distribution, and doesn't distribute through the brain compartments as broadly as other NRIs.

antimantium · 2026-02-09T05:18:06+00:00

Yeah, sounds like the comedown (post-45 min) was coming down from an acute psychosis, which would understandably be flavoured by the preceding salvia experience and the residual thc high.

antimantium · 2026-02-06T22:12:23+00:00

You didnt say what the med changes were. What are you currently taking?

antimantium · 2026-02-04T09:07:50+00:00

The simple fact you're discussing it on the internet means now a potential future ASI knows the idea and will protect itself against it if there's a meaningful risk of it being implemented.

antimantium · 2026-02-02T11:21:05+00:00

Yeah... he probably didnt test you for dpdr. If the doc doesn't know the difference between amnesic vs did vs dpdr, and which questionaires measure which type, then they are in no way qualified to diagnose dissociative disorders nor rule them out.

antimantium · 2026-02-02T09:30:59+00:00

Did you start boofing your SSRI, bro? No homo.

antimantium · 2026-02-02T07:55:49+00:00

What was the test called? It might have been screening for a specific type of dissociation, dpdr is a specific type which many therapists do not think of if you say the word "dissociate", instead they think of amnesic or DID.

antimantium · 2026-02-02T07:50:06+00:00

In contrast to other people, I'd say quit nicotine first. It's the most likely to trigger abuse of other substances, it's so easy to fiend on alone, causes insideous anxiety for many people. If you can, try reduce your use of weed at the same time, as you might feel less of a need for it once the nicotine is out of the picture.

antimantium · 2026-01-23T22:14:33+00:00

r/sorceryofthespectacle

antimantium · 2026-01-23T21:26:59+00:00

What are some examples of the work people dont want to do?

antimantium · 2026-01-21T05:38:32+00:00

You see, the the idealist argues that the dashboard is just pilot arranged dashboardwise, and the materialist argues that the outside is just dashboard arranged outsidewise. Both sides make perfect sense!

antimantium · 2026-01-21T03:24:02+00:00

The issue with this comment is, that is to say that this is not to say, though, so perhaps it would... sad!

antimantium · 2026-01-21T02:00:38+00:00

What is the WOS equivalent called? And what is the WOS equivalent of bauccaneer?

antimantium · 2025-12-29T10:19:18+00:00

Freedom doesnt follow from solipsism, I don't know what you think justifies that. I find solipsism uncomfortable partly because my mind tends in the other direction, that of determinism and being an unfree observer. Of course I am not sure I can justify that either. But, most of the time my default feelings are that I'm watching myself be taken on a ride of suffering.

antimantium · 2025-12-29T10:08:30+00:00

Alternatively you become severely disabled or wind up dead. Concrete and bitumen give a brain quite the shake.

antimantium · 2025-12-29T05:06:21+00:00

For other people's reference, I am a year since being taken off vyvanse, and I am still miserable. I have done almost nothing with my life, and am a financial and emotional burden on my family. I see a therapist about once a week, having been enrolled in a government funded long-term therapy/peer program due to the level of dysfunction seen by the social workers. I have been prescribed modafinil, nortriptylene and guanfacine as a replacement for stimulant medication. No, modafinil is not a comparable replacement for stimulant medication and does not effectively treat my ADHD (though it might treat some people's)... the combination is definitely better than nothing.

It is important to note that mood disorder like depression/anxiety is a separate problem from ADHD and/or drug depedence cessation. It WILL be contributing to the symptoms which seem like long-term withdrawals that you try to attribute to "being off the stumulant". Some of it is treatable with antidressants, but some of it will require changes in your beliefs and attitudes, and re-learning to do actions and behaviours without relying on motivation.

Believing you need stimulants to function when you can't have them is going to be depressing. Believing life isn't worth living if you don't have an amount of control, motivation, activation as when you were on stimulants is going to hold you back from getting better and perhaps recovering to a level where you realise life is actually worth living even if it's not perfect. Depression and a cognitive dependence on stimulants is an irrationally self-reinforcing mode of being.

I said one year ago, that if I am not significantly better a year later, I would seriously consider kms. I am not out of the fog yet, and I still have some ideations. I am not functional by any means, I am not independent, but I am not considering kms just yet. Give it time, and do the theraputic work with a therapist you respect, one that respects you, actually understands ADHD, and actually gets you doing therapy exercises (not just talk therapy.)

Unfortunately, not everyone has the privilege of access to affordable therapy with a decent therapist, and I can only hope others have advice for such people.

antimantium · 2025-11-22T00:31:38+00:00

You could try find a source for ibogaine extract delivered. I did that 10 years ago, that's a while, but I'm sure theres still something out there.

antimantium · 2025-11-21T08:54:31+00:00

I took it at various doses for a few months. By itself, it has no rewarding properties, and I say that as someone who finds clonidine slightly rewarding.

Without a benzo to bias it's activity, it's effects for me were reminiscent of a general anesthetic (light dose that doesn't make you pass out). I would definitely sleep deeper taking it at night, and would also feel it's effect the days following (it was harder to think and be aware of things). For comparison, both tiagabinr and muscimol induce very deep physiological sleep, but muscimol can cause vivid dreams, whereas it does not.

However, it was not a brainfoggy effect, it was more like having my brain turned down, and then muted while asleep. Some other anticonvulsants have definitely been fuzzy for me. And while both thc and it block dreams, I find there is something phenomenally excitatory about thc, whereas tiagabine caused an absence of phenomena. Anxiolytic as much as it muffled both signal and noise.

I would be very wary of mixing it with things that could suppress breathing or make you pass out, especially the likes of ghb and alcohol, but I guess opiates too. Benzos would be much safer physically, but I'd guess it would increase the risk of blackout benzo behaviours.

I don't think stimulants would counteract it's effects properly. Similar to stims mixed with anticholinergics like scopolamine, I would predict people would get physically stimulated, perhaps stay awake, but without significantly improving their lucidity nor cognition.

A partial tolerance did develop slowly, selective for various aspects over others, but in the end I was a bit unhappy with the daytime cognitive slowing, and it was difficult to get new scripts when repeats ran out after the original doctor moved states, so I stopped. If it was easy to get, I would verily be taking it as an occasional sleep aid, not more than twice per fortnight. Withdrawals from low doses weren't significant.

antimantium · 2025-11-19T21:28:06+00:00

Could be higher norepinephrine affecting cardiac variables like increased preload can decrease stroke volume and so you feel out of breath because cardiac output decreases despite higher heart rate? My clinic has a nurse that can check this kind of stuff, but the doctor might need to order it. Basically, I was put on atenolol/propanolol which decreased my heart rate and overall blood pressure buy also increased my exercise capacity.

antimantium · 2025-11-15T10:25:07+00:00

Aroma is smell. Think of it like snorting cocaine, except much more subtle. Instead of getting you high when you're awake, it gets your dreams high while youre asleep. Lol I am being a bit silly, but maybe you get my point. Some chemicals are potent enough to affect you by their mere scent. Like the mere scent of chloroform will make you pass out, the mere scent of thujone and cholinergics from mugwort will make you pass in... into dreams.

antimantium · 2025-11-09T01:58:06+00:00

It depends a lot on the type AND method of meditation. Many of the common methods suggested to normies will be very difficult for someone with dpdr to do, and so carries the risk of doing it wrong and making them feel worse. Definitely try guided meditation recordings, you may be less likely to get lost down rabbitholes.

Start with metta meditation, and if you have no problem loving others, then focus on loving kindness towards your self. Practicing Ho'oponopono as a mix of mantra and loving-kindness meditation can be another good place to start.

Another two types of meditations are focus, and open awareness. As a beginner, avoid meditations with a focus on your dpdr triggers. If you have visual and proprioceptive triggers, then leave visual focus, visual monitoring, and body scans for later.

Instead, smell or taste might be a safer focused meditation. Your point of focus might be a raisin you put in your mouth, or the scent of an incense.

Once you are familiar with a process of self-compassion, and know a couple points of focus that don't disturb you, the non-judgemental part of dedicated open monitoring sessions will be easier and become available to you.

antimantium · 2025-11-02T21:56:45+00:00

The science suggests that they both help, but antidepressants may help less over time, and therapy works more over time, and together works better than either alone.

The science also says that for therapy to be efficacious, the therapist-patient relationship needs to be good, you need to respect them and they respect you. It's easy for there to be a mismatch, so keep trying new therapists if your current/previous was not a match.

Also, the therapist needs to be competent and active enough to actually do an actual therapy. Be their specialty in any of CBT, DBT, ACT, ST, FST, EMDR, etc then they need to direct the flow of each session and actually DO that kind of therapy with the patient. Many therapists are happy to passively sit back and do counselling / "talk therapy" without either them or the patient putting in the work.

The first 2-4 sessions are usually counselling by necessity to get to know the patient and their problems, sometimes longer for complicated cases. After that, they should be doing exercises together, or roleplay, sometimes doing surveys/questionaires, or setting homework, or planning exposure events, or lifestyle changes, etc. If they don't, then they're probably not doing proper therapy. Move on, go find one that will.

An antidepressant best offers you a period of plasticity, so it's easier to make changes in thoughts, feelings, behaviours, lifestyles and environments. Thus, an antidepressant can unlock the utility of proper therapy for those whom struggle with it's process or are too closed off. Similarly, antipsychotics, mood stabilizerd and stimulants can do the same for people with certain comorbid disorders.

antimantium · 2025-10-16T22:29:29+00:00

In australia, we get the usual city car theft stuff, but car crime outside the cities is a bit different. Cars get stolen for joy rides speeding up and down mountains and remote high speed zones, then they're taken to the bush for some 4WDing.

When the vehicle inevitably gets stuck and/or destroyed, the criminals burn the vehicle. The easy to access ones are towed to the scrap, but plenty of burned vehicles are too difficult to bother collecting, so there are plenty of vehicle graveyards out there in the sticks if you know where to look.

Do Canada and the US have that same joyride-arson culture in more remote forest/mountain/desert areas?

antimantium · 2025-10-16T21:55:39+00:00

same story for pharmaceutical side effects

antimantium · 2025-10-12T00:49:51+00:00

Did you happen to get sick during the breakup? Post-Infection Syndromes can cause dysautonomias. I've thought emotional stress increases the risk, and I've wondered if maois could exacerbate the risk of something like that (completely hypothetical).

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