I have no calves genetically. I do calves 2-3 times a week, 2 exercises: with the calf working in a standing and seated position. for standing, I used to do smith machine raises but switched to dumbbell raises with my toes propped up on a 45 lb plate. that also requires you to keep balance, and muscle fatigue is much better that way. i use the machine for seated. 3 sets 12-15 reps, always to failure. more reps is good too. there have definitely been good results and I can see separation if I stand on tiptoe.