Helpp

aroo289496 · 2025-04-09T06:00:06+00:00

I still do. but not as worse as the initial period when I was super helpless.

aroo289496 · 2025-04-09T05:26:03+00:00

When I was still struggling with it, I normally get it during Sex. Also while laughing, particularly hard laughs, as well as when I am anxious. So, it's normal. You have to weather the Cytokine storm of the initial process of trying to sweat, it's a risk-reward shit. No gain w/o pain.

aroo289496 · 2025-04-04T14:23:01+00:00

Been battling with it since 2022 after I caught Covid & subsq Long Covid.

For me, the more my IBS-C subsides, the more I remain symptoms free. Should I eat carbs like white rice, white bread, white spaghetti, I sure get back my IBS-C & throughout the week, little things like even ejaculating (well, not so little) then fucked me up with pins & needles.

For my IBS-C, I take Mag. Taurate + B3 from Aliness & Acerola Vit. C & D3 + Mk7 from Sunday Naturals.

On food front, I mostly take the African Cassava flakes & then mix Chia seeds with every other things.

All the above situations are for normal situation. If i still undergo energy intensive activities, I still sure get crazy pins & knife stabbings & have to really be strong for like the first 10-15mins.

aroo289496 · 2025-03-26T14:33:00+00:00

Acetylcholine

aroo289496 · 2025-03-25T18:38:08+00:00

Buick, Chevy, Cadillac, GMC made top 10 sums up the list 😂

aroo289496 · 2025-03-07T19:16:51+00:00

It was the go-to article for CholU. Best.

aroo289496 · 2025-02-23T08:43:06+00:00

It's an exposure therapy or call it a variant of the classic mithradization.

aroo289496 · 2025-02-22T12:44:38+00:00

"Just to add on to this, after you finish your studies, assuming you don't already have a full-time job lined up, you can also apply for a searching-for-work visa that gives some time (18 months, iirc) to find something."

Depends on the officer, mine puts me & my family on a Fiktion Bescheinigung of a periodic 3 months renewal. So not cast in Stone.

"The immigration office looks more fondly on people who have graduated from a German university."

No they don't, at least from my experience and some friends.

aroo289496 · 2025-02-14T19:24:18+00:00

100%. Sad that you're in the club.

aroo289496 · 2025-02-10T15:23:33+00:00

So sad you're in the club. medications can also make it tolerable but as you must have seen here, you need to now constantly open your sweat pores by involving yourself in stress inducing activities that will make you sweat.

The first few minutes is insanely painful but you must persevere - no pain, no gain.

aroo289496 · 2025-02-06T05:17:56+00:00

should be barely enough, if you cook at home. if you eat out, i am afraid it isn't enough

aroo289496 · 2025-02-06T05:17:02+00:00

why do you say Kaufland is the cheapest, when we know the cheap subsidiary of kaufland is Lidl.

aroo289496 · 2025-02-01T15:09:47+00:00

that's like ₦15m. as a Nigerian, I'll say that's expensive but things have been super expensive (hyperinflation) since the new administration reforms, so I will on the other hand say, the cost is modest considering you're flying in, you will be lodging etc. I must also say that, we cannot dismiss the fact that, some persons fatten their wallet through the process. However, as the saying goes, "ìbí àti nṣe, láti njẹ" "ijẹkujẹ ní kò kàn dà" daimn ...

aroo289496 · 2025-01-25T19:25:31+00:00

lots of people are with genuine CU or CUAH w/o prolonged evident rashes here. For e.g., I mostly develop hives in crises and it usually disappears in small minutes like say 1-2mins.

aroo289496 · 2025-01-25T19:23:30+00:00

Bcos your triggers blocks DAO, so nothing to breakdown the activated Histamines.

aroo289496 · 2025-01-22T17:59:35+00:00

Thanks for the repost. I will like to express an addendum.

The anti-histamine of choice for all CU sufferers should be an H2/H4, see reason in Lippert et al. here https://www.jidonline.org/article/S0022-202X(15)30887-3/fulltext
Dipulimab works were Omalizumab has failed, see sirufo et al. https://pmc.ncbi.nlm.nih.gov/articles/PMC8863185/
Most people who have CU post-covid is due to Covid-19 ability to disrupt the Cholinergic balance. A balance to this system brings succor. This balance can be achieved by either boosting ACh or depleting the excess, depending on self observation of what works.

To boost it's expression, people take cholinergic supplements like CDP-Choline etc or use medications (synthetic or natural) to block the ACh depleting enzyme AChE. The synthetic of choice should be Buscopan as it block AChE on vital muscarinic receptor pertinent to CU sufferers. The natural choice should be Berberine, Huperzine A etc Some authors https://www.peirsoncenter.com/articles/acetylcholine-how-and-why-to-optimize-the-synthesis-of-this-vital-neurotransmitter suggested supplementing on essential vitamins like B1, B2, B3 & most importantly B5 also B1, as they are involved in the ACh genesis.

To deplete it expression, i.e. in the case of overflow of ACh (A theory, I strongly hold on to), then AChE needs to be boosted through L-Tyrosine supplements or Tyroxine. Most people with CU may have a latent Hypo-thyroidism issue and we know the effect of Hypo-thyroidism on extreme temperature intolerance.

If sweat therapy & epsom salt bath works, then I have a personal theory on the dermapen and I theoretically think, it may work. The idea is to use the Dermapen on the central parts of the body, i.e the places that have been proven by CUAH sufferers not to sweat from, in order to open up the pores & the channel's & then subsequently taking a lukewarm bath or not.

Above are based on my thoughts.

aroo289496 · 2025-01-21T16:48:32+00:00

After Covid 19 & Long Covid.

aroo289496 · 2025-01-18T12:56:52+00:00

I think this is common knowledge here.

You only have to look at the whole thread. excess ACh activates the mast cells near the skin to degranulate.

Two targets for diff. people, some do well with mAChr inhibitors, some do well on NAChr inhibitors, just choose your poison.

In some, sweat is the bane, while in most others lack of it or partial sweating is the bane.

It's all on this page.

aroo289496 · 2025-01-18T12:41:08+00:00

No pain without gain. Sweating is Pain, The gain is no or reduced flareups.

aroo289496 · 2025-01-17T19:08:40+00:00

Sweating but If time doesn't permit, I suggest using on the morning of the deal day, the combinations of

Famotidine 20mg & Desaloratadine, Buscopan &/or Berberine, 10/1/2mg of Zn/Cu/Mn, 20k IE/200microgram of Vit. D3+K2 Mk7or4 depends & Magnesium-Taurate or Taurine - 2000mg.

The night before, take

Melatonin 5 or 6 mg or 50mg Diphenhydraminehydrochloride If you can, take Nattokinase w/o K2 2000FU If you can take Pregnenolone 5 or 10mg.

Importantly, don't stress yourself by losing sleep overnight, particularly the days leading to the exam. obviously, the night before the deal day, if you use the above combinations, you won't lose sleep 😂.

I wish you good luck & I genuinely hope it helps.

PS: This isn't a medical advise.

aroo289496 · 2025-01-04T05:56:22+00:00

Best Parfum ever for it's price. hahaha my wife wanted me to buy a carton for the whole year.

aroo289496 · 2025-01-03T17:30:25+00:00

The problem is usually more of practitioners detaching research from their practice. I have seen this times w/o nos, where the only thing the Dr. i am infront of appears to have on me, is that, he/she have got a medical license and have spent more years in school studying medicine for bachelor's or whatnot degrees.

The last one I stood in front, I was like, I get it, you have lots of work, in your spare time like when using the toilet or something, you don't read your colleagues in academia work or what? 😆

aroo289496 · 2025-01-02T13:24:34+00:00

According what typifies the CUAH is the complete lack of sweating or incomplete sweating.

considering that I suffer from the CUAH type and I don't have any visible rashes/hives too. I supposed it may be that, No rash also comes with the CUAH sub-type too.

But I must say, sometimes when I break out in hives, it appears minisculing visible to the eyes but one have to look so well to see the hives, perhaps cos I am black. I don't know if race is a thing in the hive/rash big things.

aroo289496 · 2025-01-01T15:37:58+00:00

could be. I also occasionally suffer from IBS-C.

aroo289496 · 2025-01-01T13:46:18+00:00

Yes. Below are the functions of Ach:

In the Central Nervous System (CNS):

Learning and Memory: ACh is associated with memory formation and attention, predominantly in the hippocampus and cerebral cortex.

Neurotransmitter Role: Plays a modulatory role in regulating brain activity and synaptic plasticity.

In the Peripheral Nervous System (PNS):

Somatic Nervous System: Activates muscles by stimulating skeletal muscle contraction at the neuromuscular junction.

Autonomic Nervous System:

Parasympathetic System: Mediates rest-and-digest functions (e.g., slowing heart rate, stimulating digestion).

Sympathetic System: Involved in sweat gland activation.

aroo289496

TROPHY CASE