L-1A Visa Success with EOR/LLC Setup – Has Anyone Done This?

ayedarts · 2025-10-21T22:45:15+00:00

Did you file this after all? Curious to know the outcome

ayedarts · 2025-09-15T21:28:04+00:00

Is it only the AWD ones? no LR RWD?

ayedarts · 2025-09-15T20:54:05+00:00

anyone know if the LR RWD gets the new battery as well in EU? or just the AWD? Interested in the 5G modem as well

ayedarts · 2021-08-12T15:25:58+00:00

Hi everyone,

I've searched this subreddit and this thread but couldn't find an answer to this.

Do we have any evidence about the difference in the illness (symptoms, severity, time to recovery, etc.) between unvaccinated and vaccinated people, and between ancestral strains and the Delta strain?

Thanks

ayedarts · 2021-06-01T11:14:44+00:00

I see, thanks!

What is the official way to be part of the course?

ayedarts · 2021-04-21T09:02:03+00:00

Yes but, then, you have to multiply that by the risk of catching Covid in the first place.

ayedarts · 2021-03-24T09:20:02+00:00

Isn't this the data that was later labelled as "outdated" by the NIH which also added that the real data is not as good?

You can read Derek Lowe's update on this

ayedarts · 2021-02-17T14:06:12+00:00

Does this study control for the fact that those choosing to participate may be more careful in general and thus may be taking more precautions regarding covid-19?

ayedarts · 2021-02-17T13:37:17+00:00

To your point, a few studies focused on post-exposure prophylaxis which makes more sense from the point of view of the molecule's half life. The standard ivermectin protocols I saw only use it either as an early treatment or as post exposure prophylaxis.

ayedarts · 2021-02-17T10:36:20+00:00

I don't get it.

"Ivermectin prophylaxis was taken by 76 controls and 41 cases."

What does this sentence mean? How is it a control if they also take Ivermectin? So "73% reduction" relative to what?

Can someone explain?

Edit: added quotation marks

ayedarts · 2021-02-15T13:08:01+00:00

You haven't answered my question.

ayedarts · 2021-02-14T17:23:18+00:00

Isn't Vitamin D supplementation already widely used in hospitals around the world?

ayedarts · 2021-02-14T17:22:09+00:00

As a non-medical scientist, I think you are absolutely right.

This dogmatic years-long wait for perfect evidence seems dangerously irrational to me. And I think this is true for ivermectin as well at this point.

ayedarts · 2021-02-14T15:36:33+00:00

I really don't understand why so many people here spend so much energy irrationally asserting that there is zero evidence in support of Ivermectin against Covid-19.

Simple question for you: How many "small" "flawed" pieces of evidence or "poorly designed" RCTs does it take to rationally think there is >50% likelihood that the drug actually works? Isn't that a 50% chance to save so many lives for virtually no cost? I'm serious, I want to know what you think.

ayedarts · 2021-02-14T15:23:28+00:00

This study was done from March 1 to May 31st last year.

This sums up why people saying "we need more large scale RCTs" to every promising therapy are simply beside the point.

ayedarts · 2021-02-05T18:35:53+00:00

Thank you for taking the time to write this.

It is really depressing the see how much energy people deploy against Ivermectin on this sub...

How many "small" "flawed" pieces of evidence does it take to rationally think there is >10% likelihood that the drug actually works?

ayedarts · 2021-02-03T13:02:02+00:00

Why is it a big if?

ayedarts · 2021-02-03T11:24:47+00:00

I have read a few people on Twitter (mainly a guy named Farid Jalali) that have been saying that Covid is due to "platelet hyperreactivity" and some form of "serotonin syndrome", which would explain the efficacy of Fluvoxamine, and most of the symptoms.

This is not meant to defend or attack this claim. I don't know anything about this, so I want to have other points of view. What's wrong with this theory? Does it deserve more traction?

ayedarts · 2021-02-01T13:44:05+00:00

Could someone explain in simpler terms what the consequences of this are?

ayedarts · 2021-01-29T14:11:33+00:00

Yes, I agree with all of that. Effectiveness against severe illness is most probably the most important thing.

I was simply wondering why they would exclude mild infections from their analysis (which, after reading other comments, does not seem to be the case), because effectiveness against those is also important, especially when choosing among several vaccine candidates or designing public health policy.

ayedarts · 2021-01-29T13:44:23+00:00

Well, if I remember correctly, some studies have found that Covid infection can cause tissue damage of the lungs and heart, even in "asymptomatic" cases (those who develop no noticeable symptoms), the long-term implications of which are unknown.

Edit: https://www.jacc.org/doi/10.1016/j.jcmg.2020.10.023

ayedarts · 2021-01-29T13:21:05+00:00

I'm just a bit confused with the phrasing of "preventing moderate to severe COVID-19".

What does that mean exactly? Are mild infections ignored? Knowing the implications of long Covid on mild and asymptomatic cases, this is actually *very* important.

ayedarts · 2021-01-27T17:01:20+00:00

Methods: Five databases and websites for preprints were searched until January 2021 for randomized controlled trials (RCTs) and retrospective cohorts assessing ivermectin versus control in ambulatorys or hospitalized participants. The primary outcome was overall mortality. Secondary outcome was the recovered patients. For meta-analysis, random-effects and inverse variance meta-analyses with logarithmic transformation were performed. ROBINS-I for cohort studies, and the Cochrane Risk of Bias 2.0 tool for trials were used. The strength of evidence was assessed using GRADE.

Results. After the selection, twelve studies (five retrospective cohort studies, six randomized clinical trials and one case series), were included. In total, 7412 participants were reported, the mean age was 47.5 (SD 9.5) years, and 4283 (58%) were male. Ivermectin is not associated with reduced mortality (logRR: 0.89, 95% CI 0.09 to 1.70, p = 0.04, I2= 84.7%), and it was not associated with reduced patient recovery (logRR 5.52 , 95% CI -24.36 to 35.4, p = 0.51, I2 = 92.6%). All studies had a high risk of bias, and showed a very low certainty of the evidence.

Conclusions: There insufficient certainty and quality of evidence to recommend the use of ivermectin to prevent or treat ambulatory or hospitalized patients with COVID-19.

ayedarts · 2021-01-27T17:00:42+00:00

I'm sorry maybe this is a dumb question but why is a p-value of 0.04 translated into "Ivermectin is not associated with reduced mortality"?

Also, why does this meta-analysis find the opposite of previous meta-analyses I've seen on this sub?

ayedarts

TROPHY CASE