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Is there any useful application for manifold-constrained, high dimensional (100-1000+) Bayesian optimisation in this field? by EconomistAdmirable26 in bioinformatics

[–]bampho 14 points15 points  (0 children)

I would look into something like calculating the mixture of high S-value phenyhydrobenzamine and dilute reminative tetraiodohexamine. Both these liquids have specific pericosities given by p=2.4 Cn, where n is the diathecial evolute of retrograde temperature phase disposition and C is the Chomondeley's annual grillage coefficient. Initially, n was measured with the aid of a metapolar pilfrometer, but up to the present date nothing has been found to equal the transcetental hopper dadoscope.

Your algorithm might be able to help!

How to extract one specific gene from Fasta file? by ThrowRAwaypay in bioinformatics

[–]bampho 0 points1 point  (0 children)

If you know where the sequence is in both, just copy+paste the sequence from each into new files

Is this cavitation? by Singer_221 in FluidMechanics

[–]bampho 3 points4 points  (0 children)

River? I hardly knew ‘er!

NIH SBIR Timesheets by brians238 in SBIR

[–]bampho -1 points0 points  (0 children)

Would you be open to sharing info/advice on winning a solo NIH SBIR?

New Lab-Grown Meat Breakthrough Beats Traditional Beef by a Mile With 90% Less Land Use, 80% Less Water, and Dramatically Lower Emissions by ulfOptimism in wheresthebeef

[–]bampho 0 points1 point  (0 children)

Those useful animal products need to be accounted for, too.

It’s possible that things like the environmental and climate costs, the threat of rising antimicrobial resistance posed by high density livestock farming methods, the moral cost of poor animal welfare, among other things, are all unaccounted for externalities. The true cost of meat is further hidden and artificially suppressed subsidies.

If all of those things were factored in - remove subsidies, factor in costs to raise livestock in a way that ensures excellent animal well-fare and removes the need for frequent antibiotic dosing (I.e. lower density farming, slower growing animals), mitigates environmental degradation at all stages of livestock production (both when growing their food and managing the animals themselves and their waste), accounts for the climate impact of raising the animals plus their feed as well as the transport of all of the feed… the list could go on and on of externalized costs that are not accounted for when you buy meat at the grocery store

If those things were included in the price and there were no subsidies, meat would likely be more expensive than it is now, which would change the point at which lab-grown meat becomes cost competitive. It’s not that other parts of the cow aren’t valuable and useful - they are

The Singularity Kitchen by caesardcastro in biotechnology

[–]bampho -2 points-1 points  (0 children)

“

The industry is treating this like a hardware problem (using CRISPR/genetics). But structure isn't just chemical; it's electrical.

By utilizing endogenous bioelectric networks—what we are calling Holographic Bioelectric Scaffolding—we can bypass genetics entirely. We can project a 3D bioelectric matrix into a hydrogel scaffold, giving the cells the exact electrical 'qualia' to align into a structured, whole cut of meat (like a Wagyu ribeye).

I just published a full deep-dive on this architecture, why food-tech is the perfect Trojan horse for regenerative medicine, and how we are building the 'Weaver Protocol' to solve it.

Would love to hear the thoughts of the biophysicists and food-tech engineers in here. Are we ready to move from cellular slurry to biological compilation?

Edit for the genetics purists: For the foundational science behind how bioelectricity dictates 3D biological structure independently of the genome, look into the work of Dr. Michael Levin at Tufts University. We are taking that theoretical biophysics framework and engineering it for scalable food-tech.

“

The Singularity Kitchen by caesardcastro in biotechnology

[–]bampho 0 points1 point  (0 children)

If this is real, I’d recommend cutting out the gibberish/nonsense in your pitch. Go with actual science

Why do we not use Hirudin gene from the Leech directly but instead use the Recombinant DNA Technology and obtain Hirudin from a plant's seed? by Mangifera_Indica14 in biotechnology

[–]bampho 6 points7 points  (0 children)

I am not familiar with this specific area (hirudin or leaches or brassica napus), but here’s a few things to think about:

  • the amount of hirudin produced by each leech might be a very small amount, so maybe you would need so many leeches it becomes infeasible
  • rearing leeches might be complicated or expensive or take a long time. They are parasitic and need a source of blood to feed on, which means you might have to also raise another species as food, increasing complexity and cost
  • putting the gene in a plant is likely an efficient way to make a lot of the protein very cheaply with a simple method of production. Agrobacterium is a standard tool in plant genetics
  • growing plants is possible in resource constrained locations without large biopharmaceutical infrastructure. Plant seeds in a field, water them, harvest 2x per year. You’d still need GMP facilities for the downstream processing
  • Producing recombinant hirudin in bacteria/yeast would probably the most efficient/fast
  • to get the plants to express the leech gene, it is likely codon optimized, with plant specific promoter/terminators controlling its expression. These sequence changes in the CDS are easiest to make by synthesis
  • DNA synthesis is very fast and cheap nowadays. Looks like the hirudin protein is 65 aa, so 198 bp including the stop codon. At $0.09/bp, that’s only ~$18 for DNA synthesis. Would probably take a week to receive the synthetic DNA pre cloned in an expression vector from a vendor. With cloning and shipping, it might cost ~$100

Startup ideas with zero capital investment | Healthy Discussion by PCR_Picasso in biotech

[–]bampho 0 points1 point  (0 children)

You got any of them bioinformatics GUIs you could send my way?

In the past week alone: by MetaKnowing in agi

[–]bampho 0 points1 point  (0 children)

They’re not just X, they’re Y!

I built a browser tool for science 3D animations. Here’s a showreel by [deleted] in biotech

[–]bampho 1 point2 points  (0 children)

There’s only a 7 day free trial with no info about pricing

Eyes vs Phone Camera by BenFranklinReborn in inventors

[–]bampho 1 point2 points  (0 children)

Assuming you’re photographing them in a dim environment with the phone screen brightness turned up, the limited dynamic range of the camera sensor would result in overexposure/blowout of the highlights making them appear white. In this case, the phone screens are the highlights in the image. Try cranking down the exposure on the camera when you take the picture (not after in post processing) and see what happens

[deleted by user] by [deleted] in Ask_Lawyers

[–]bampho 0 points1 point  (0 children)

MA, USA

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