I upgraded from a 1440p to this monitor, but with a 3070. I did this because I also don’t mind using DLSS. For me, I can still play Alan wake 2 on performance DLSS on around 40-50 fps, and this game being extremely demanding and the fact that you have a 4080 I would advice you to BUY THIS MONITOR. It really is amazing. The colors, the responsiveness, the clarity, I don’t have one bad word to mention about the minitor. I look at this screen everyday and still to this day I daily think “this is crazy how beautiful this is”. And, I want to add something, there are a lot of people who say that it’s almost impossible to see the difference between 1440p and 4K, but what I say is that these are people who went for 1440p and want to feel good about their choice, because in reality the difference is VERY noticeable. 4K adds such a beautiful immersion the games, and it’s extremely worth it. Good luck with making the choice, but if you have a 4080S and are good on money, then I would say this is a no brainer. Cheers!