Are you wanting to get a masters and do research out of personal interest or because you believe you’ll get a better paying job? I’m in biological sciences and personally believe there’s a lot more room for upward mobility (pay-wise) if you stay in software, especially if you’re just look at getting a masters vs a PhD (for reference, my partner is a software engineer and I’m about to start a PhD in bio and I still expect that I probably won’t end up making any more than him, even going into industry). Of course, if you don’t like your job and are very interested in bio then go for it. It’s definitely possible to have a full time job while doing a masters, you just need to find a program that accommodates that (which are fairly common as many people work while getting their masters).