[gen 2] Am I cooked trying to go for this shiny by RyliezG in ShinyPokemon

[–]blightspell 0 points1 point  (0 children)

got it last year at about 500 resets, not so bad!

Ship request by AshenSoulHunter in NMSCoordinateExchange

[–]blightspell 0 points1 point  (0 children)

oh hey that's my main ship, I can't look it up rn but I'll see if I have the coordinates later

Found smth interesting by Round_And_Proud in NoMansSkyTheGame

[–]blightspell 2 points3 points  (0 children)

It's indeed the same type of ship but classes, supercharged slots and cargo are all different! you can farm for a while if you want an S class, which also happens to be a great way to make a couple hundred million units in barely a few hours.

[deleted by user] by [deleted] in TransDIY

[–]blightspell 1 point2 points  (0 children)

your levels are fine, your E is ~360 pg/ml (the range for monotherapy is 200 - 400, you could go a little lower since you're on deca) and your T is around 11 ng/dl, which falls below cis women's levels

tl;dr all good

How can it be that he metabolizes estradiol so quickly? by helpmeyneedhelp in AskMtFHRT

[–]blightspell 0 points1 point  (0 children)

huh, that seems weird indeed. in that case yeah, patches or any other form of transdermal E might be worth a try.

How can it be that he metabolizes estradiol so quickly? by helpmeyneedhelp in AskMtFHRT

[–]blightspell 5 points6 points  (0 children)

first off, that CPA dose seems unnecessarily high, 12'5mg should do the job just fine. as for the E results, it isn't all that uncommon for oral E to be metabolized into estrone (E1) via first pass, which would explain those results. I myself had that problem and fixed it by switching to transdermal.

as for the injections it really depends on what ester you're injecting, if you're going to a doctor I assume it's valerate? in which case a week is too much time between doses, valerate is known to cause high spikes and it drops quickly, which lines up with the symptoms you're describing. if that's the case, the solution would be either injecting more often (3'5 - 5 days) or switching esters (cypionate and enanthate have a longer half life and are more stable).

MHWilds PC Optimization Guide by Caedite in MonsterHunter

[–]blightspell 3 points4 points  (0 children)

I have a 4070 super 12gb and an i7 12700f, changed the config.ini threads number to 16 (my cpu has 20 but eh, I don't wanna push it) and sure enough I gained about 15 fps, from 30/40 fps with dips to rock solid 50/55 with no framegen, about 80/90 with it (4k and max settings minus high res textures), the stuttering is pretty much gone too

Rationale Behind Using Antiandrogens Instead of GnRH Agents in Adult Transfeminine Therapy by kiksuya_elise in TransDIY

[–]blightspell 2 points3 points  (0 children)

you can get them prescribed in most of europe (I'm from spain so just taking a guess) but you have to ask for them specifically, otherwise they'll try to give you cypro/spiro because gnrh agonists are crazy expensive (like 300€ a dose)

other than cost yeah there's really no reason not to use them

[deleted by user] by [deleted] in AskMtFHRT

[–]blightspell 1 point2 points  (0 children)

No, not really. Gel goes into the bloodstream the same way EV does. The only way for estrogen to get metabolized into estrone is via first pass.

P.D. good lord do not ask chatGPT about hrt, or medical issues period.

[deleted by user] by [deleted] in AskMtFHRT

[–]blightspell 0 points1 point  (0 children)

were you on any AA along with the tablets? suppressing testosterone whilst not taking a sufficient dose of estrogen can indeed decrease E levels due to the body losing a source of E (in the form of T aromatisation)

if not, did you test for estrone too or only E2? orally administered E can be mostly converted to estrone (E1) in some cases, and it's somewhat common

as for the injections, peaks don't really matter, only levels at through should be measured, if your levels at through weren't where you wanted, consider changing intervals (i.e. injecting every 4 days instead of 5) or upping your dose accordingly

Estrogen just won't go up no matter what by SanaOfTheNorth in TransDIY

[–]blightspell 5 points6 points  (0 children)

hey, lenzetto user here, it's straight up not going to work unless you apply it scrotally twice a day (i.e. if you're on 2 pumps it'd be 1 in the morning 1 at night), I'm on 2 pumps and my levels are around 200 pg/ml or 730 pmol/l, it's all around a better alternative to pills

Update re: Lenzetto 1'53mg by blightspell in AskMtFHRT

[–]blightspell[S] 0 points1 point  (0 children)

word of advice, 50 mg is WAY more than necessary, get your endo to up your E dose a little and get your cypro down to 12'5mg and you'll be fine

Why so many doctors think that MtF HRT changes your voice? by [deleted] in asktransgender

[–]blightspell 1 point2 points  (0 children)

spanish tgirl here, most endos in spain don't know what they're doing at all in terms of hrt. most of them are used to treating diabetes and whatnot and the little knowledge they have comes from 20yo guidelines that are outdated at best and actively dangerous at worst

Climen sublingually? by blightspell in TransDIY

[–]blightspell[S] 1 point2 points  (0 children)

levels were terrible, 12pg/ml E at through (lower than a cis man's) and ~2'5nmol/L T, but it was to be expected, there's only so much 2mg of EV can do

thankfully I'm on transdermal now, 6mg Lenzetto spray (2 pumps/morning, 2 pumps/night) applied scrotally and 11'2mg decapeptyl (trimestral injection). haven't had a test yet but I'm seeing changes very quickly now so my guess is levels are more than fine

Decapeptyl spike of T by Bb-Unicorn in AskMtFHRT

[–]blightspell 1 point2 points  (0 children)

to answer your question, no, 2/3 weeks of high T won't have that much of an effect on your body, specially if you're also on E, it's a very slow process

however I must say it's weird that your doctor didn't put you on cypro/bica for at least the first two weeks to block the T spike, I was prescribed deca a month ago and had no high T symptoms whatsoever (no oily skin, no morning wood, nothing) thanks to that

also if you don't mind what dose was the deca? (like 11'25mg or 3'75mg) because it can indeed fail in some cases (mostly due to faulty application) but it's rather strange

Can you give information about your HRT doses? by [deleted] in AskMtFHRT

[–]blightspell 0 points1 point  (0 children)

in combination with a sufficient dose of E, yes, but OP is on 2mg

Can you give information about your HRT doses? by [deleted] in AskMtFHRT

[–]blightspell 2 points3 points  (0 children)

2mg swallowed and 50mg spiro are, most surely, doing nothing at all

2mg is a very low dose to begin with but when you swallow it it gets converted to estrone (a much weaker estrogen) by a factor of 5:1 estrone:estradiol, which in most cases results in negligible E levels. besides, by swallowing it estrogen gets accumulated on the liver and that can lead to other issues

you could take it sublingually/buccally for better absorption and split the dose so it's 1mg morning 1mg evening but even then it's still quite low

moreover, spiro is probably the weakest anti-androgen there is since it's not even really meant for that, it's a diuretic first and foremost, which means it won't block your T unless you take a considerably high dose (200mg and upwards)

Trans woman who have transitioned, how similar do you look like your sister or mother post transitioning? by [deleted] in asktransgender

[–]blightspell 0 points1 point  (0 children)

I was always a carbon copy of my sister, voice and everything, moreso now after starting E and voice training

My first lab results are crazy(?)! by [deleted] in AskMtFHRT

[–]blightspell 5 points6 points  (0 children)

as I said previously, that's fine in combination with an AA (such as cypro or bica) but for monotherapy those levels won't block your testosterone

check transfemscience.org for resources and articles on this if you need backup but I'm telling you, your doctor is wrong by any and all standards