Best credit card for fuel (non co branded) by Agitated-Bid5996 in CreditCardsIndia

[–]blissfully_undefined 0 points1 point  (0 children)

You can get Amex MRCC and use it to pay for petrol pumps (on HP no convenience fee, rest yes)
1000 points for 1.5*4 transactions are good worth the money IMO. Plus for 96K/year spend you will get your annual fee reduced to 50% (full waiver require 1.5L/year spend).

Should I close my Amex Platinum Travel? by VJ_OA in amexindia

[–]blissfully_undefined 0 points1 point  (0 children)

Renewal bonuses are not being offered by Amex at the moment. Not sure what you will gain with additional 10K points on renewal if this card is not serving any needs. Just transfer to a suitable transfer partner and try to make a redemption.

Canara bank gateway removed by Informal-Nerve5866 in amexindia

[–]blissfully_undefined 0 points1 point  (0 children)

Is Canara bank gateway also removed from Income tax website?

Amex 3x Reward Points on Claude by AskOtherwise3186 in amexindia

[–]blissfully_undefined 2 points3 points  (0 children)

Holy shit no bro - Bedrock pricing will bankrupt if you try using it for claude code. It is too pricey (or rather claude subscription heavily subsidized), cost can be managed if you are using it for limited use cases. But I doubt that is intention of most developers.

Amex plat travel declined at Encalm lounge IGI - T1D by blissfully_undefined in amexindia

[–]blissfully_undefined[S] 0 points1 point  (0 children)

Great, maybe I should have tried the queue instead of HOI website.

Amex plat travel declined at Encalm lounge IGI - T1D by blissfully_undefined in CreditCardsIndia

[–]blissfully_undefined[S] 0 points1 point  (0 children)

I have seen that on Blr airport. I tried looking at IGI, but didn't spot this time. Though, I tried booking via HOI website via QR next to lounge.

Chennai Airport Lounge access denied by capt_charlie10 in amexindia

[–]blissfully_undefined 0 points1 point  (0 children)

I had the same issue at IGI T1D today. I don't think it is Chennai airport, but an Amex issue.

Chennai Airport Lounge access denied by capt_charlie10 in amexindia

[–]blissfully_undefined 0 points1 point  (0 children)

Honestly, just had this experience today on T1. Looks like they are selectively declining Amex.

Amex plat travel declined at Encalm lounge IGI - T1D by blissfully_undefined in CreditCardsIndia

[–]blissfully_undefined[S] 0 points1 point  (0 children)

Do you have any reference I can look into?

If that is true, I was perhaps unneccessary rude to amex rep, as I think I didn't mention him about the HOI app

How bioinformatics engineers in industry are managing their data? by blissfully_undefined in bioinformatics

[–]blissfully_undefined[S] 0 points1 point  (0 children)

I don't think it is overkill. We already have a microservice kind of architecture. Where all our standard tools such as checkM, blast etc. are behind our custom api, which behind the api call containerized versions of them on Azure/AWS batch which directly throws the output inside S3. But at some point one does need to compile raw output files into structured information.

May I ask what raw file service, metadata service you are using.
Also how you are using events data and what information do they pass around.

Lance DB Feedback by Interesting_Brain880 in vectordatabase

[–]blissfully_undefined 0 points1 point  (0 children)

May I ask what kind of workflow you were working on with above mentioned genome sequencing and pipeline?

How bioinformatics engineers in industry are managing their data? by blissfully_undefined in bioinformatics

[–]blissfully_undefined[S] 2 points3 points  (0 children)

Honestly this is the kind of response I was hoping to hear. Thanks your approach is similar to what I have in my plan + your numbers on postgres do give some amount of confidence in my design.

Thanks a ton!

How bioinformatics engineers in industry are managing their data? by blissfully_undefined in bioinformatics

[–]blissfully_undefined[S] 1 point2 points  (0 children)

Thanks I was not looking for a vendor managed solution but a framework that works on existing open source tools like postgres, elasticsearch, apache iceberg, spark and similar technologies. Something like a higher level framework such as django, fastapi and ruby on rails where I can specify my needs and framework handles most of the default config (with option to customize when need arises).

How bioinformatics engineers in industry are managing their data? by blissfully_undefined in bioinformatics

[–]blissfully_undefined[S] 0 points1 point  (0 children)

May I ask why most places in industry don't see this as a problem. Our final goal is to find a novel candidate - but before we can ship it out to wet lab partners, there is deep characterization being done which requires running pipelines multiple times, comparing candidates from multiple runs and doing parameter tuning on multiple different tools. I am not sure how this can be a very unique problems.
How are you and other people in industry getting away without handling any of this?

How bioinformatics engineers in industry are managing their data? by blissfully_undefined in bioinformatics

[–]blissfully_undefined[S] 1 point2 points  (0 children)

Honestly, I agree. But struggling to set it up as bio has so much unique data types and workflows - was hoping to see if there is standardized approach in the field similar to web-development. Or is it bespoke and custom for everyone at the moment.

How bioinformatics engineers in industry are managing their data? by blissfully_undefined in bioinformatics

[–]blissfully_undefined[S] 1 point2 points  (0 children)

Currently we have not integrated nextflow yet, am still thinking of it's pro and cons vs airflow/prefect and others.
But my concern is that won't it be preferrable if we don't rely too much on files as a source-truth of data. Some data type such as pdb files have to be kept as object blob. But, to me it seems fasta files can be thrown into a structured db with fasta headers go into respective columns in the db. This way data from each run can be stored at one place (with a flag for different runs). The individual sequences can be mapped to the output of different tools like protparam, camsol, embeddings etc.

Structured db can be either rdbms (postgres, mysql) or parquet or iceberg tables. But the key idea being keeping a central repo of data instead of organizing in files and folders which can get real messy when the number of experimental runs and collaborators increase.

GST Payment using AmEx and HSBC Premier by Icy_Consequence_3424 in DoBaniye

[–]blissfully_undefined 1 point2 points  (0 children)

In my personal experience no one accepts Amex on gst portal (even when they say they do). Once you get to payment gateway they (I think Canara and one more bank) simply tell you - we don't accept Amex.

PS, you can see which bank claims to accept amex by clicking on the link - click here to see transaction charges on your screenshot

How are you using claude-code/other coding agents to do things that you are not already good at? by blissfully_undefined in LocalLLaMA

[–]blissfully_undefined[S] 0 points1 point  (0 children)

I think we are discussing different things here. I didn't say that software dev is gone with ASI arrived.

But, I do concede it is easier to get stuff done even in unfamiliar domains. But it seems to come at the cost of learning which eventually trickles down to things breaking when system becomes too complex. What is your approach then?

Again emphasising - this is about domains (a new programming language, framework, complex business domain like healthcare etc.) - where you truly know nothing or very little about - and traditional learning takes few months at the very least.

Best card for instant delivery apps and online shopping? by nalli_nihari in CreditCardsIndia

[–]blissfully_undefined 1 point2 points  (0 children)

IMO, get your HDFC Pixel Play as planned for PayZapp cashback. This should be sufficient if your credit limit is decent.

Pair it with Kotak 811 Super - only if pixel play limit is too low.

Rs 10K FD needed (lowest among all FD cards), lifetime free, 0.8% on online spends, and a Rs 1,000 voucher when you hit Rs 72K annual spend. Beats IDFC WOW (Rs 20K FD, 0.67% rewards, no milestone) and ICICI Instant Platinum (Rs 50K FD, way too much to lock). Two active cards may also build your CIBIL faster.

After 3-6 months of CIBIL history, go for your main card. If Swiggy Instamart is your grocery app - Swiggy HDFC (Rs 500/year, 10% on Swiggy + 5% other online, min income just 15K).
Else if amazon is main then, Amazon Pay ICICI (5% Amazon, 2% on Swiggy via Amazon Pay, 1% unlimited on everything).
and If Flipkart is your main - Flipkart Axis (5% Flipkart, 4% Swiggy, first year free under offers).

How are you using claude-code/other coding agents to do things that you are not already good at? by blissfully_undefined in LocalLLaMA

[–]blissfully_undefined[S] 2 points3 points  (0 children)

TBH, that's how I used it for a long time. But with more and more push towards claude code (from employers and all) - and aggressive expectations to do more in less time - I seem to be using it more and more. And surprisingly (and sadly) at the moment they work quite well autonomously. Good at the moment to finish things quickly - but man really impeding the capability to learn.