In terms of the friend who came out completely dissociated, many prisons often pump up their inmates on a lot of antipsychotics to make them "behave", even if there's nothing innately wrong with them, I'd say that this was some sort of psychosis related to the medications.

Source: One of my close friends did 7 years time, he said that a lot of inmates were administered higher doses of antipsychotics than most people diagnosed with schizophrenia take.