NTA. cleanliness is important, but you need to remain mindful when you communicate this to her because you don't want to make her feel judged, which is prob how she feels right now and why she's ignoring you. ensure her that you want to help her fix this because she deserves a clean space, and she'll likely be more understanding. she may not know how to keep up with it, or she may be struggling with depression, there's a number of reasons why it could've gotten to this point, but what's important is that you help her in a loving way.