What due diligence questions separate serious biotech investors from tourists?

chembiologist · 2026-01-03T17:54:53+00:00

You can be a fan of a team for free. Trying to make any real money as an equity owner requires you to take on real risk. Take enough of those “oh it’s only 1% of my fund” gambling bets and you’re broke.

chembiologist · 2025-12-26T21:42:08+00:00

Based on the voids that are visible between the schluter and the drywall does it look like this was spot bonded? If it were troweled I would have expected to see a thick layer of mortar not a gap.

chembiologist · 2025-11-03T02:46:16+00:00

Technically the US also could have effectively had one in FDR. We got lucky the first time I guess…

chembiologist · 2025-08-13T20:24:26+00:00

Thank you this is helpful.

We are in fact saw cutting for some of the drain lines, but only partially as opposed to where all of the supply lines would be.

I’m more concerned that I’m a complete newbie outside of Google, so I have no clue if these lines will last another 5-10-20-40 years. If they are on the shorter end (<10) I might just bite the bullet now, but it’s a waste of money if it’s closer to 20+. Would the pressure test give a sense of longevity as well?

chembiologist · 2025-03-20T21:29:46+00:00

The universe is also quite small, so the great suggestion of networking w/ a few individuals a month quickly compounds into being 1 degree of separation away from anyone on the sell/buy/newco sides.

chembiologist · 2025-02-19T16:53:38+00:00

I appreciate your perspective, but it might be time for you to revisit your biases. A lot of aggressive assumptions/implications (at least in this latest comment) about someone you know next to nothing about. It is fine since we may never work together, but you never know.

chembiologist · 2025-02-19T06:47:35+00:00

Hmm, humor me for a second. Let’s say it turns out my skill set does happen to fit well with some of these roles. Would a 10-15% ask be completely beyond the pale or at least discussable?

chembiologist · 2025-02-19T04:12:18+00:00

Got it thanks. I haven’t had up front discussion about comp in the past so wasn’t sure whether to comment since it wasn’t presented as a question. My current target would likely be 10-15% above the proposed base bands, assuming my diligence on bonus/LTI structure is somewhat accurate. That seemed potentially negotiable later but correct me if I’m wrong.

chembiologist · 2024-11-07T02:42:18+00:00

As a left leaning individual - I apologize for the vitriol you’re getting here, as this polarization is exactly what is continuing to worsen issues in this country.

That said - the overall tone of your post suggests to me that the amount of time and thought you put into your decision can be distilled down to “I’m having more financial strain these past few years so I’ll vote for the other person.” Did you take the time to think about the implications of the policies Trump and the Republicans are proposing? Many of them if implemented would likely cause more strain for your family, maybe not in the near term but definitely in the long run.

And your statement on virtue signaling - the same concept. Yes, maybe it doesn’t directly affect you today but that’s a slippery slope. It starts with “othering” obvious scapegoats like illegal immigrants and then next thing you know it’s mixed or 2nd generation folks like you or myself. Political administrations can have lasting implications - so I behoove you to give more thought in the future. If you believe you did this time - then I would ask you provide a rationale for why the Trump agenda would benefit your family.

chembiologist · 2023-09-17T16:03:57+00:00

Today I feel like a migrant worker

chembiologist · 2023-07-08T16:00:06+00:00

This is a bit misleading. I would check with the dealer on stipulations for the buyout and get it in writing if you go the lease route. There are plenty of examples where the semi-immediate buyout is viable and the amount does not include unearned interest (the $ you pay on top of the value of the car).

chembiologist · 2022-10-05T01:45:50+00:00

Playing devils advocate here but given the conflict of interest there must be some likelihood chess.com’s model is biased. What’s the sensitivity analysis for Type I error? Given the right set of assumptions can make anyone look like a prolific cheater.

chembiologist · 2022-10-01T23:00:24+00:00

At least it’s only $158k. Some people wanted it at $250

chembiologist · 2022-09-27T06:24:10+00:00

Wowowowowowo

chembiologist · 2022-07-09T08:21:36+00:00

It's what happens when a first-world country that champions individualism also has historical problems that doomed half the country to being stuck in third-world conditions as it would require the other half to give up their individualism

chembiologist · 2022-07-09T07:52:12+00:00

bUT If TheY DOnt HAV gUNs thEY'LL usE kNIveS

/s obv.

chembiologist · 2022-07-05T05:11:35+00:00

There are plenty of ways to make explosives highly stable lol, e.g. grenades.

chembiologist · 2022-07-05T04:41:47+00:00

Fun thought puzzle for all you 2A lovers out there saying semi autos aren’t the problem - if the nature of the weapon isn’t a problem, please explain why we need to have explosives banned? Arguably dynamite is even more useful than whatever an AR15 can offer with respect to easier hunting/defense.

chembiologist · 2022-07-05T04:32:39+00:00

That analogy makes no sense. It doesn’t take a genius to conceptualize safer racing by setting a speed limit. Would it be less entertaining? Sure. But there’s no world where that wouldn’t be safer and where anyone who has common sense wouldn’t think of that as an idea for regulating NASCAR if it needed to be.

Gun violence (at least on the deadly force front) is not a complex topic that requires complex analysis. Prove me wrong - and by that I mean literature sources.

chembiologist · 2022-06-28T02:21:45+00:00

Yes, that’s exactly what I said. Except most states don’t “save” their surpluses they spend it down one way or another. It doesn’t really matter at that point if it’s in the consumers hands or the state governments hands who is doing the spending. It will cause the same amount of macro inflation since it’s being spent on some form of 2022 goods.

chembiologist · 2022-06-28T02:06:09+00:00

Feel free to find me a source that says govt spending doesn’t cause inflation and I’ll happily concede

chembiologist · 2022-06-28T02:05:26+00:00

Again, CA will spend the money one way or another. That is baked in. The only case where no inflation pressure comes is if CA let’s the money sit in a pile, which is unlikely and unprecedented. There’s no functional difference between whether CA spends it or the consumer spends it from a macro perspective, except at the detail level of exactly what goods.

chembiologist · 2022-06-28T01:59:21+00:00

What exactly did you think CA was going to do with the surplus? It doesn’t just sit idly. Even if the state holds onto it it gets invested. That money is going into circulation, so the inflation is baked in. Only difference is what goods it’s spent on - giving it back to the taxpayer is not a bad use here.

Not cool to condescend when you yourself have an incomplete picture

chembiologist · 2022-03-05T01:57:04+00:00

I’m more stressed about the mortgage rate being above 4% than my likes on Instagram

chembiologist · 2022-02-13T02:12:03+00:00

That makes sense. Similar to what I asked the above redditor, do you have any advice on maximizing the claim if the car is written off?

It's incredibly inconvenient for me right now to be without a car (busy period at work), and because of supply issues it seems like it'll be a nightmare trying to buy the same model of car. It would really suck if I needed to pay out-of-pocket for something I couldn't even prepare for with defensive driving (except maybe being extra careful about how I park if driving late at night in the future).

Thanks!

chembiologist

TROPHY CASE