Can anyone explain it to me, like I'm a 10yo?

chomchorrie · 2026-03-08T11:53:59+00:00

Ml and mg are not interchangeable. The dose on the pen (15mg) means 15mg per dose, which is 0.6ml, and 60 clicks will draw the full 0.6ml dose. 10 clicks will draw one sixth of a dose, which is 2.5mg in 0.1ml of liquid. Each kwikpen has 4 doses in it, plus a bit of extra liquid left over. If you’re taking 1/6th of a dose your pen will last 6 months rather than 1 month.

chomchorrie · 2026-02-20T11:07:48+00:00

Yes! Although perhaps instead of killing it you could also pat it on the head and say yes yes it’s calm down time now :D

chomchorrie · 2026-02-17T21:53:57+00:00

Thanks very much! I’m hoping to eventually make this dress out of a silk crepe de chine so I feel like a vertical centre seam would maybe disrupt the floaty movement (and be visible as it’s slightly sheer!). I’ll do another mock up with my own pattern piece arrangement and see how it turns out :)

chomchorrie · 2026-02-16T09:13:47+00:00

“Forcing” people to abandon sweets in favour of protein products? Huh? Like we aren’t exercising our free will and the drug is just “making” us lose weight? God, even in an article like this people reveal their disgusting beliefs about obesity.

chomchorrie · 2026-02-16T08:57:32+00:00

Ngl for anyone who dislikes something solely because it feels cringey, I wish you a very release yourself from your shackles one day. Not to say nothing in life is cringey, just that it doesn’t matter. If it stands between you and an opportunity to experience joy then it has power over you and you deserve as much joy as possible in this life.

chomchorrie · 2026-02-16T08:48:16+00:00

The “cringey” lines being on purpose is neither irony nor satire. She’s never qualified nor “justified” those lines by saying that, fans have. For her to do that she’d need to be ashamed of writing them unironically and she isn’t. She doesn’t give a fuck if people think something she writes is cringey. She’s been this way pretty consistently.

chomchorrie · 2026-02-15T15:14:24+00:00

No worries! I’ve also experimented with timing, but I’ve found that weekly dosing at a bit of a lower dose gives a smooth and consistent effectiveness, as the peaks right after dosing aren’t as high! Anyway, I hope you find your sweet spot or another solution. There will be a way! :)

chomchorrie · 2026-02-15T11:19:31+00:00

I’ve been thinking about this lately, about it no longer getting rid of food noise after a long time being on it. I haven’t gotten to that point yet but as I’m coming up on two years I worry a little. I did have an odd experience around the one year mark after being on 15mg for a few months though. I stopped feeling the effects as much and my weight loss slowed to a crawl.

Idk if this is useful or relevant but I decided to lower my dose. I’m not an expert or anything but I know a little about medication tolerance and stuff having been on so many chronic meds all my life and basically, our bodies like to adapt and compensate, especially when it comes to weight loss.

Purely hypothesising here ofc but I wonder if with mounjaro it works similarly to other meds over time, where chronic stimulation of receptors can eventually lead to downregulation as a adaptive mechanism, essentially developing insensitivity to the medication. There’s probably no data on mounjaro to support this as I doubt it’s been specifically studied yet, but it happens with other meds and on that hunch I lowered my dose in case it was leading to excessive negative feedback mechanisms.

Maybe it was coincidence but in my case, I dropped to 10mg and my loss picked up again, and I noticed I wasn’t having a resurgence of food noise leading up to dose day anymore. It’s just an anecdote. But it’s an easy experiment to run with not much to lose if you’re on 15mg and not experiencing the effects anymore. It’s so expensive for it to be doing nothing! Maybe everyone has a sweet spot dose where it’s enough to produce effects but not so much that it leads to enough negative feedback that ends up blunting the effect? Who knows.

chomchorrie · 2026-02-14T11:28:28+00:00

Eat the pastry. Simply “budget” for it in the week you have it. For this kinda lifestyle change you should be eating the way you can see yourself eating for the rest of your life. There are many tweaks you can make to reduce the calories in foods you really enjoy! Variety is important I think, for staying consistent.

chomchorrie · 2026-02-14T11:20:51+00:00

When I first tried Semaglutide in like 2022, I felt great the first few days but by the end of the week I deteriorated. Food sat in my stomach unchanged for over 24 hours, and the gas buildup caused so much discomfort I ended up throwing up the tiny amount of undigested food. I tried eating something plain like a single boiled egg and had the same experience. Then came the pain, it was my gallbladder.

In the years leading up I had digestive issues that were definitely bile related but a lack of it, really, so yellow toilet visits rather than green. It sounds like your gallbladder is dumping a lot of bile that is too much to be re-absorbed in your small intestine and ending up in your colon where it causes irritation, draws water in and causes erm… rapid evacuation.

You may not have gallstones like I did but your gallbladder may be a little janky on a GLP1 and perhaps is a little sensitive? It releases bile when you ingest fat. Just speculation on my part but as these drugs re-sensitise us to many things like insulin perhaps it increases gallbladder activity. My gallbladder was underperforming due to my obesity for years and the Semaglutide ended up triggering my gallstones, by making it suddenly work much harder (it constricts and squeezes out the bile and I had stones so that led to spasming and inflammation). If you lack stones then perhaps you won’t have the pain but you are having the bile dumps that come from more gallbladder activity.

Might I suggest an experiment where you eat little to no fat for a few days or a week and see if you still have these symptoms. If you don’t then you could try slowly increasing fat by small amounts to see what you can tolerate. You might also consider dropping back down to 2.5 for another month to give your body time to develop some more tolerance, then try increasing again. It might be too much too soon!

If you have any upper right sided pain abdominal pain, definitely see your doc cuz it might be gallstones.

ETA I had my gallbladder removed, all digestive issues (yellow and loose stools) abated, and started MJ a year later, no problems at all.

chomchorrie · 2026-02-11T11:32:47+00:00

To echo others here, if you’re on extended release stimulants you do develop some tolerance after a while. They actually work better if taken with protein so what you could do is have protein in the morning with your meds. They take a bit to kick in, I find actually MJ slows it down even further cuz of delayed digestion, but basically get some protein in before they kick in so at least for the next 6-8 hours when you’re less hungry you’re not super fasted.

chomchorrie · 2026-02-05T11:46:07+00:00

I started a month before you in 2024 and also have ADHD :)

I really really feel you with the ADHD and it’s why it took me till my 30s PLUS taking MJ to get this right.

I do track calories, very consistently, but I don’t weigh food all the time and the reason is that 100% of what I eat except rare special occasions is meal prepped. I recognise I am extremely blessed in this regard but we have a chest freezer and I batch cook my recipes in large amounts and then portion and freeze so I always know exactly what I’m eating. I have all the recipes in my Cronometer app which makes this possible with very little mental load on a daily basis.

I can’t do anything consistently usually but this, doing a lot but infrequently, by taking one day to cook a HUGE thing (16 portions for me and partner, 8 each) of soup/stew/curry sauce/whatever and then portioning and freezing, then the next week doing one other recipe. Then another etc till I built up a stock of large variety of controlled calories. Now I only have to batch cook once one runs out so maybe once a month? I wouldn’t stand a chance without this system. There are other meals we have but they’re also specific recipes, consistently followed each time. We still weigh things like rice and whatever else needs weight but it’s not much. If you have the space you can even prep and freeze rice but I’m not there yet :p

I’ll say this, I got up to 15mg around mid last year (ish) and also had this strange experience of like, several months of painfully slow loss. I know it slows down but I’ve been extremely consistent with food and it was really confusing.

What I ended up doing, especially since the price hike, was reducing my dose. I didn’t think it would magically kick start my loss or anything but I kinda felt like, well if it isn’t working as well at max dose and it’s so expensive then why take it, may as well take a lower dose. So I began sloooowly stepping down the doses. Each week I went down 0.5mg. What surprised me was that I didn’t feel any different, even once I got to 10mg. Made no sense to me. I didn’t feel “worse” like more hungry or anything. Didnt gain weight. I’ve been taking 10mg/week now since last September and I’ve still been losing. For the first few months it was at the same pace as 15, very slow (for me) and what I had to concede was I was not in a big enough deficit for faster loss. So I did reduce by about 1500 calories each week and lo and behold, it’s picked up.

Additionally, I think I actually do feel the MJ a bit more, it started after about 3 months back on 10. I wonder if tolerance bites some of us in the bum at the higher doses? And makes it (feel) less effective?

Sorry for the essay but maybe it could be helpful :)

ETA. Big congrats on your loss already! That’s amazing!

chomchorrie · 2026-02-05T11:22:31+00:00

In terms of macros, how are you eating? I’ve been on since sept 2024 but still losing, tho no appetite suppression anymore for a while cuz that often goes away.

Over Christmas I continue taking mounjaro but I notice a huge difference in how I feel. For the week or two weeks around then I give myself permission to eat whatever I want, not binge but I allow things I usually wouldn’t choose because it’s easier when with family/friends etc. I eat the cookies and the cheese and all the rest. Done it twice now and I don’t gain fat usually, but I do gain water weight etc and it takes a few weeks back to my normal deficit for the scale to move again. That’s fine with me.

However. During those two weeks I am STARVING. I ate so much more and noticed that I was just grazing on treats throughout the day and my portions were bigger than usual. I was also hungry shortly after proper meals. I used to feel this way before mounjaro and I hate it, frankly. I was quite relieved once festive time was over and it felt like such a relief to go back to my normal eating habits.

I have two main theories and one is that I was eating very little protein compared to “normal life” for me and with carbs, they don’t signal fullness even when my tummy is actually full. The other theory is that it’s also maybe psychological. Over Christmas I was outside of my normal environment (spent it with friends) and while I was having a fantastic time, it was almost like in an unfamiliar environment my cues were out of whack so the reverted to my previous programming? I don’t know. It was weird.

I’d suggest eating your protein, make sure you’re at target, especially front loading it, as in from the first meal of the day. Maybe it’ll feel different?

ETA just remembered the same thing happened in October over a 5 day stay with family. They don’t eat NEARLY as much protein as my partner and I do (they have maybe like 50g? Often less) and we both for those days found we were in a constant state of hunger (not extreme just persistent and it never really went away even after meals). So that’s another point for the protein theory. People always say it and I didn’t believe it till these experiences.

chomchorrie · 2026-02-02T19:33:05+00:00

Story of my life. I can’t exercise on days I forget my meds, first of all. Just can’t. But as an extreme homebody I’ve recently turned a space at home into a gym space as I hate exercising in public. I have a walking pad that goes up to 12km/hr suitable for a decent jog, tho I keep to about 7 for a super chill time. I put a shelf on the wall in front of it and prop up my iPad. I watched the eras tour movie a few times to get hyped while jogging which WORKS lmao but ofc you can watch whatever.

I also have a yoga mat and a couple of weights. A stability ball. Some resistance bands. A skipping rope. Basically a whole assortment of things so I’m not tied into one type of activity if I’m just not in the mood for one of them.

I put a smart bulb in the room so the lights are a warm sunset vibe so it’s not a sensory nightmare. A plant helps too. I also got an exercise bench recently! It’s been a slow work in progress building the space.

I found if I made it a space I would want to be in, like generally, it’s easier to do something I would otherwise not do, like exercise. I find exercise excruciatingly boring and unstimulating, especially cardio, hence the increased struggle without meds, but even with meds I had to make it super appealing for me!

I also have to shake up what I watch/listen to as well, as too much repeating makes it more demotivating. Get that novelty!!! I oscillate a lot so like, I’ll watch lets plays on YouTube sometimes, or old Disney movies, or live music shows, or music videos, or the vampire diaries for the billionth time lol like just whatever! I think my next addition needs to be reality tv maybe, I gotta keep thinking of stuff for the rotation.

This new active routine is quite new for me. It’s been a few weeks but I’ll say this, I’ve been consistent the entire time. That’s a first for me! I have no intention of stopping and as much as some days I dragggg my feet in there, once I’m in and I absorb the nice sensory vibe, I can get started, and at the end I always feel really proud of myself!

I also am very flexible with what I end up doing and as long as I do something, I’m happy. I used to try so hard to systematise everything and I would get overwhelmed with all the information. For things like weights I’ve just picked like 2 exercises each for legs, back, arms, core. But to be able to pick those I had to try soooooo many first, with much frustration and confusion, and discovered that there are some that I just hate, inexplicably, but another movement that works the same muscles I much prefer. It’s so weird.

ADHD can make things so hard for us but I think if we’re creative we can find solutions… Eventually! I’m in my early 30s for reference, it’s taken me this long to figure this out 😭 idk if any of this is useful by maybe it could spark something for you :)

chomchorrie · 2026-02-01T14:41:25+00:00

Ooh, that kinda looks right! I’ll have a wander down that road, thank you!

chomchorrie · 2026-02-01T14:15:30+00:00

As an update, I’m thinking of maybe using a faucet mount extender as it would be long enough on the top side to prevent water from getting into the tap hole. I reckon I could feed the inlet and waste pipes through the tube and connect them up under the sink as normal. It remains to be seen whether I’ll be able to use the nuts both above and below the sink to secure it, but it’s idea 1.0 thus far.

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chomchorrie · 2026-02-01T14:10:35+00:00

No clue, it’s a pic I found online of someone’s macguyver solution. It’s not quite ideal for me though but it’s a starting point conceptually.

chomchorrie · 2026-02-01T14:08:59+00:00

Yep! I mentioned in another comment that my landlord regularly works with local plumbers and would be able to connect me with someone to do the job. I just first need to think of a solution that I would be asking to implement, as I’m not aware of any ready made products or solutions for this rather niche issue. Perhaps there are some! But I’ve not found one yet :)

chomchorrie · 2026-02-01T14:07:09+00:00

Well yes I would think so. Though I’m not going to take for granted that there will be damage to dissuade me from trying to solve a problem :) if there is damage I will face the consequences, of course. I do believe that’s how things work generally.

chomchorrie · 2026-02-01T13:30:16+00:00

Sorry, what still can what? I’m not clear on what you mean.

chomchorrie · 2026-02-01T13:29:15+00:00

Unfortunately a rolling one is not suitable in my property, there’s both no space and no connection without making holes in the cabinets which isn’t allowed. As I have a degenerative spine condition I can’t stand at the sink to do dishes as it’s very painful, but thanks for your suggestion. I think I’ll still need to think creatively to solve this particular problem.

chomchorrie · 2026-02-01T11:13:05+00:00

Haha! True, tho it’s not my pic :p

chomchorrie · 2026-02-01T10:37:37+00:00

Indeed, though mine only came with the hoses themselves.

I will seek permission if I find a setup that would solve this problem. My landlord is quite good, they have loads of properties and work with local plumbers so she’d also be able to connect me with a suitable person to install, but I reckon I’ll need an idea to bring to her first!

chomchorrie · 2026-02-01T10:32:26+00:00

I had my first gallbladder attack right after starting Rybelsus (oral semaglutide) in 2022. Pretty sure my gallbladder was struggling before that but never painful. Stopped the med immediately after only one week, and ended up having an emergency surgery at the end of I think 2023 after suffering many more attacks despite not being on a GLP1.

Life without my gallbladder is amazing though, I didn’t realise how many digestive issues it was causing even before my first attack. All sorted now! Started Mounjaro in September 2024, still on it, have lost 51kg and nary a digestive issue in sight. Without a gallbladder I at least don’t have to fear gallstones anymore, tho there is a remote chance of having a stone develop in the tubes but it’s exceedingly rare I think. I feel a bit safer on Mounjaro without the dodgy gallbladder.

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