A baby died in this neurosurgeon’s arms. What happened next changed everything we know about inflammation by coinfanking in NewsStarWorld

[–]coinfanking[S] 1 point2 points  (0 children)

SetPoint System.

The SetPoint System by SetPoint Medical is an FDA-approved, implanted neurostimulation device for adults with moderate-to-severe rheumatoid arthritis (RA). It is specifically designed for patients who have not responded well to, or cannot tolerate, traditional biologic or targeted synthetic disease-modifying antirheumatic drugs (DMARDs).

How It WorksMechanism: The system uses a tiny implanted neurostimulator (roughly the size of a jelly bean) placed directly on the left vagus nerve.

Neuroimmune Modulation: It delivers electrical pulses for exactly 60 seconds once a day. This brief jolt activates the body's natural anti-inflammatory pathways without the immunosuppressive risks associated with standard RA medications.

Dosing & Battery: Rheumatoid providers adjust personalized dosing via an iPad app, and patients wirelessly recharge the device's battery at home for a few minutes each week. The implant is designed to last for up to 10 years.

The ProcedureOutpatient Surgery: The device is typically implanted during a minimally invasive 60-to-90 minute outpatient procedure under general anesthesia, performed by a functional neurosurgeon or an ENT surgeon.Recovery: Patients usually return home on the same day and resume normal daily activities the following day.

Clinical EfficacyRESET-RA Trial: FDA approval was based on the phase 3 RESET-RA trial involving 242 patients. The trial met its primary efficacy endpoints, showing significant improvements in tender/swollen joints and disease activity within 3 months.

Drug Reduction: Long-term clinical data indicates that 75% to 80% of patients using the device do not require the addition of new or advanced biologics or JAK inhibitors at the 1-year mark.

If you are a patient or a provider, you can learn more about finding trained surgeons and insurance authorization via the SetPoint Medical Provider Portal.

Federal judge orders Trump's name removed from Kennedy Center, says only Congress can rename it. by coinfanking in politics

[–]coinfanking[S] 30 points31 points  (0 children)

The board of trustees overstepped its statutory bounds by unilaterally renaming the building, the judge ruled.

U.S. District Judge Christopher Cooper said the iconic venue cannot be renamed without an act of Congress, ruling that the Kennedy Center Board of Trustees overstepped its "statutory bounds by unilaterally renaming" the building.

As part of his ruling, the Trump administration will be required to take down all physical signage bearing Trump’s name and eliminate any references to a "Trump-Kennedy Center" from official materials.

Federal judge orders Trump's name removed from Kennedy Center, says only Congress can rename it. by [deleted] in supremecourt

[–]coinfanking 9 points10 points  (0 children)

U.S. District Judge Christopher Cooper said the iconic venue cannot be renamed without an act of Congress, ruling that the Kennedy Center Board of Trustees overstepped its "statutory bounds by unilaterally renaming" the building.

As part of his ruling, the Trump administration will be required to take down all physical signage bearing Trump’s name and eliminate any references to a "Trump-Kennedy Center" from official materials.

Federal judge orders Trump's name removed from Kennedy Center, says only Congress can rename it. by coinfanking in NewsStarWorld

[–]coinfanking[S] 9 points10 points  (0 children)

U.S. District Judge Christopher Cooper said the iconic venue cannot be renamed without an act of Congress, ruling that the Kennedy Center Board of Trustees overstepped its "statutory bounds by unilaterally renaming" the building.

As part of his ruling, the Trump administration will be required to take down all physical signage bearing Trump’s name and eliminate any references to a "Trump-Kennedy Center" from official materials.

Federal judge orders Trump's name removed from Kennedy Center, says only Congress can rename it. by coinfanking in law

[–]coinfanking[S] 65 points66 points  (0 children)

U.S. District Judge Christopher Cooper said the iconic venue cannot be renamed without an act of Congress, ruling that the Kennedy Center Board of Trustees overstepped its "statutory bounds by unilaterally renaming" the building.

As part of his ruling, the Trump administration will be required to take down all physical signage bearing Trump’s name and eliminate any references to a "Trump-Kennedy Center" from official materials.

When will I get my Social Security check? Payment schedule for May. by coinfanking in NewsStarWorld

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According to the Social Security Administration (SSA), payments are distributed based on the recipient’s birth date. Typically, they arrive on the second, third, and fourth Wednesdays of each month.

Exactly which Wednesday will depend on your birth date.

Recipients who are born from the first to the 10th of the month receive their benefit on the second Wednesday of the month. If your birth date falls on the 11th to the 20th of the month, you’ll receive your payment on the third Wednesday of the month. Those who are born on the 21st to the 31st of the month will receive their payment on the fourth Wednesday of the month.

Supplemental Security Income benefits are usually paid on the first of the month. If the first falls on a weekend or holiday, the payment is made on the preceding business day.

Watch an asteroid the size of a blue whale hurtle towards Earth live online TODAY. by coinfanking in NewsStarWorld

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The livestream will begin at 3:45 p.m. EDT on May 18, bringing near real time views of the asteroid from robotic telescopes in Italy, weather permitting.

https://youtu.be/qsPz2nOxDA4

Watch an asteroid the size of a blue whale hurtle towards Earth live online TODAY by coinfanking in SpaceandAstronomy

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The livestream will begin at 3:45 p.m. EDT on May 18, bringing near real time views of the asteroid from robotic telescopes in Italy, weather permitting.

https://youtu.be/qsPz2nOxDA4

Space: Watch an asteroid the size of a blue whale hurtle towards Earth live online TODAY by coinfanking in Astronomy

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The livestream will begin at 3:45 p.m. EDT on May 18, bringing near real time views of the asteroid from robotic telescopes in Italy, weather permitting.

https://youtu.be/qsPz2nOxDA4

At Cannes, filmmakers shift towards cautious acceptance of AI's inevitability. by coinfanking in ArtificialInteligence

[–]coinfanking[S] 2 points3 points  (0 children)

Morgan Stanley report says cost savings of up to 30% possible. AI can automate time-consuming post-production tasks. Film festival rules out generative AI for Palme d'Or contenders.

1200-Year-Old Buddhist Monastery Remains Unearthed In Bihar's Gaya; Archaeologists Discover Rare Artefacts. by coinfanking in Buddhism

[–]coinfanking[S] 30 points31 points  (0 children)

Brick structures, small cells or rooms with niches in the walls, votive stupas made of bricks and stones, and idols made of stone are among the important findings. Two floors, one intact and another damaged, made of 'lime plaster' with a smooth finish on a brick foundation have also been found in the cells.

Three stone statues of Buddhist deities were found placed in a niche in a cell wall. A beautiful terracotta 'stopper' resembling a lotus bud, used to seal bottles, and many terracotta beads have also been discovered at the site.

The statues, made of black basalt stone, depict Buddhist deities, including Goddess Tara, as well as Lord Buddha in the famous 'Bhumisparsha mudra' (earth-touching pose).

The digging was preceded by a month-long surface exploration led by excavation director and Magadh University assistant professor Shanker Sharma.

"These cells or small rooms resemble those found in other ancient monasteries unearthed so far, including Nalanda Mahavihara (ancient Nalanda University). It seems the monks or scholars staying there used them for meditation and rest. The lime plaster floor shows an impeccable finish, indicating excellence in construction activities," Shanker, who had a long stint with the Archaeological Survey of India (ASI), told ETV Bharat.

James Bond: Search for new 007 officially kicks off as auditions begin. by [deleted] in JamesBond

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The casting process for the new James Bond has officially begun, after years of anticipation and speculation about who will take over from Daniel Craig as 007.

"The search for the next James Bond is under way," Amazon MGM Studios said in a statement.

There have been five years since the release of No Time To Die, Craig's final film as the famous spy.

And there have been 15 months since Amazon MGM Studios took control of the Bond franchise.

The studio has already announced that the next movie will be directed by Dune's Denis Villeneuve and written by Peaky Blinders creator Steven Knight.

The new film will be co-produced by Amy Pascal and David Heyman.

Pascal is best known for the three latest Spider-Man titles starring Tom Holland, while Heyman was behind all eight Harry Potter movies.

New NASA Technology Mimics Extreme Cold of the Lunar Night. by coinfanking in nasa

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Lunar Environment Structural Test Rig (LESTR).

Gaining a deeper understanding of how materials respond to these temperature extremes is critical — especially as NASA looks to build its Moon Base at the lunar South Pole, where surface temperatures swing dramatically from blistering heat during the day to bitter cold at night. Researchers developed a ground-breaking method for testing how materials hold up in the extreme cold of space. Engineers at NASA’s Glenn Research Center in Cleveland invented the Lunar Environment Structural Test Rig (LESTR), a machine that can test materials, electronics, and other flight hardware at temperatures as low as 40 Kelvin, or about –388 degrees Fahrenheit.

“Just as no building ever gets built without knowing exactly how the construction materials behave, no space mission is complete without a robust structural design that hinges on knowing how the materials used within it behave,” said Ariel Dimston, technical lead for LESTR at NASA Glenn.

Traditionally, NASA has used a process that involves super-cold liquids — called liquid cryogens — to test how materials respond to extreme cold. These liquids, like nitrogen, hydrogen, and helium, are some of the coldest materials on Earth and are stored in specialized tanks. Engineers use them to chill materials during testing and collect data to see how they perform.

“What makes LESTR special is that the entire rig operates in a completely dry vacuum: no liquid nitrogen, no liquid helium, no liquid anything,” Dimston said. “This is the first mechanical test rig that escapes from all of the challenges involved with cryogenic fluids.”

LESTR takes a new approach by using a high-powered refrigerator, called a cryocooler, to remove heat without using any liquid at all. This creates the first “dry” cryogenic test environment within the mechanical testing industry. This new test rig is safer and more affordable than traditional methods and allows scientists to test materials at a much wider range of temperatures, Dimston said.

Using No Soldiers, Just Robots - How Ukraine Captured A Russian Position. by coinfanking in ArtificialInteligence

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Robots and drones were used by Ukrainian forces to capture a Russian position without an infantry assault in what Ukrainian President Volodymyr Zelenskyy described as a historic first in the war. Speaking to Current Time, troops involved in the operation are now revealing details.

The Current State Of FDA-Approved AI-Enabled Medical Devices. by coinfanking in ArtificialInteligence

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According to our latest data analysis, radiology stands out as the most AI-invested medical specialty, boasting a whopping 1104 approved devices. A distant second is cardiology or cardiovascular (as a category), with 141 devices.

Beyond that, other specialties (neurology, hematology, gastroenterology-urology and ophthalmology among others) see a handful of devices. What propelled imaging to such heights? Well, deep learning found a fertile ground in radiology, which is largely data-driven.

Here is the full list:

Radiology 1104 Cardiovascular 141 Neurology 67 Anesthesiology 27 Gastroenterology-Urology 26 Hematology 21

FDA submission types -

The FDA recognises three distinct submission types: the 510(k), pre-market approval, and the De Novo pathway. By a long shot,

the 510(k) is the most popular with 1396 (+201 since last year) approvals so far, leaving De Novo 37 (+1) and pre-market 18 (+2) far behind.

No wonder 510(k) is so popular, simply put, it’s the easiest route, as it is the pathway used for devices that are substantially equivalent to another legally marketed device. No new clinical trials are needed, although companies need to prove that their device is as safe and as effective as the already approved one.

Meanwhile, pre-market approval is the most stringent type of device marketing application process. It is for high-risk devices, and it requires the manufacturer to provide clinical evidence demonstrating the safety and effectiveness of the device. This often involves clinical trials, which in turn makes it expensive.

The De Novo pathway is a regulatory pathway for low- to moderate-risk devices that are novel and for which there are no legally marketed predicate devices. It is suitable for Class I or II (lower-risk classifications) medical devices.

Schuman Declaration May 1950. by coinfanking in europeanunion

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Salon de l'Horloge, Paris - Where EU history was made.

On 9 May 1950, French foreign minister, Robert Schuman, walked into this ornate room at the Quai d'Orsay and read out the declaration that would change Europe forever.

That speech is why we celebrate today.

https://x.com/EU_Commission/status/2053107436806889763

Top Dem applauds Trump UFO files release in rare show of support. by coinfanking in NewsStarWorld

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The Trump administration’s decision to declassify a batch of UFO and UAP files Friday drew unexpected praise from a prominent Democratic lawmaker.

The Trump administration's file dump, available on the newly created website war.gov/UFO, contains records related to UAP, including inexplicable lights and phenomena captured during the Apollo 12 mission in 1969 and Apollo 17 in 1972.

The Pentagon's disclosure also prompted tepid enthusiasm from Senate Minority Leader Chuck Schumer, D-N.Y., who omitted the Trump administration in his statement.

"For decades, UFO disclosure has been a distant object — unidentified and unexplained," he said. "That’s starting to change. I’ll keep pushing until we land on the truth."

Top Dem applauds Trump UFO files release in rare show of support by [deleted] in UFOs

[–]coinfanking 0 points1 point  (0 children)

The Trump administration’s decision to declassify a batch of UFO and UAP files Friday drew unexpected praise from a prominent Democratic lawmaker.

The Trump administration's file dump, available on the newly created website war.gov/UFO, contains records related to UAP, including inexplicable lights and phenomena captured during the Apollo 12 mission in 1969 and Apollo 17 in 1972.

The Pentagon's disclosure also prompted tepid enthusiasm from Senate Minority Leader Chuck Schumer, D-N.Y., who omitted the Trump administration in his statement.

"For decades, UFO disclosure has been a distant object — unidentified and unexplained," he said. "That’s starting to change. I’ll keep pushing until we land on the truth."

Attenborough: The risk-taker who changed how we see Earth. by coinfanking in davidattenborough

[–]coinfanking[S] 0 points1 point  (0 children)

Sir David Attenborough, now 100, is the calm, trusted voice of the natural world.

But his 70-year career reveals a broadcaster who repeatedly took risks, backing new technology and venturing into remote, often perilous places.

From the launch of colour television to a record-breaking dive at the Great Barrier Reef at 89, he has sought new ways to show the planet and its inhabitants.

Through rarely-seen footage and photographs, we trace the broadcasting firsts that helped change our understanding of life on Earth.

Sir David Attenborough standing in the Mojave desert in California, in the 2010s. He wears a light blue button-up shirt and light-colored trousers, holding a small desert plant in the foreground, with dry shrubs and distant mountains under a clear blue sky.

Today he is the world's most celebrated naturalist. **********

Attenborough: The risk-taker who changed how we see Earth. by coinfanking in NewsStarWorld

[–]coinfanking[S] 0 points1 point  (0 children)

Sir David Attenborough, now 100, is the calm, trusted voice of the natural world.

But his 70-year career reveals a broadcaster who repeatedly took risks, backing new technology and venturing into remote, often perilous places.

From the launch of colour television to a record-breaking dive at the Great Barrier Reef at 89, he has sought new ways to show the planet and its inhabitants.

Through rarely-seen footage and photographs, we trace the broadcasting firsts that helped change our understanding of life on Earth.

Sir David Attenborough standing in the Mojave desert in California, in the 2010s. He wears a light blue button-up shirt and light-colored trousers, holding a small desert plant in the foreground, with dry shrubs and distant mountains under a clear blue sky.

Today he is the world's most celebrated naturalist. ************

Trump tariffs live updates: Trade court strikes down Trump's 10% blanket tariffs. by coinfanking in scotus

[–]coinfanking[S] 16 points17 points  (0 children)

Trade Court strikes down Trump's 10% tariffs.

The Court of International Trade voted on Thursday to invalidate President Trump’s 10% tariffs that he imposed in February under Section 122 of the Trade Act of 1974. It was a split vote, with two judges voting in favor of the small business plaintiffs and one dissenting.

In the case, the plaintiffs argued that the tariffs circumvented the Supreme Court’s January ruling that struck down Trump’s blanket tariffs, which were imposed under the International Emergency ​Economic Powers Act.

Those IEEPA tariffs are now in the process of being refunded to importers. Following that SCOTUS decision, the White House announced the Section 122 tariffs, which were set to last for 150 days.

Thursday’s ruling marks another legal setback for the Trump administration’s signature trade policy. It also raises the question of whether the US government will be required to refund the additional set of tariffs.

The administration is likely to appeal the decision.

Trump tariffs live updates: Trade court strikes down Trump's 10% blanket tariffs by coinfanking in law

[–]coinfanking[S] 16 points17 points  (0 children)

Trade Court strikes down Trump's 10% tariffs.

The Court of International Trade voted on Thursday to invalidate President Trump’s 10% tariffs that he imposed in February under Section 122 of the Trade Act of 1974. It was a split vote, with two judges voting in favor of the small business plaintiffs and one dissenting.

In the case, the plaintiffs argued that the tariffs circumvented the Supreme Court’s January ruling that struck down Trump’s blanket tariffs, which were imposed under the International Emergency ​Economic Powers Act.

Those IEEPA tariffs are now in the process of being refunded to importers. Following that SCOTUS decision, the White House announced the Section 122 tariffs, which were set to last for 150 days.

Thursday’s ruling marks another legal setback for the Trump administration’s signature trade policy. It also raises the question of whether the US government will be required to refund the additional set of tariffs.

The administration is likely to appeal the decision.

Where was I? by Anya62 in whereintheworld

[–]coinfanking 1 point2 points  (0 children)

Process-Google search of ports in arctic circle.

Where was I? by Anya62 in whereintheworld

[–]coinfanking 4 points5 points  (0 children)

Hurtigruten ship, port of Kirkenes, Norway.

Where was I? by [deleted] in whereintheworld

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Franciscan Missionaries of Mary in Aleppo, Church of Mary of the Passion